Реализация пациентоориентированного подхода в работе детских медицинских сестер первичного звена медицинских организаций Забайкальского края

In modern health care, the principles underlying patient-orientated healthcare, aimed at preserving the health of the patient, as well as the productive cooperation between the medical caregivers and the patient, are becoming increasingly important. The article presents the results of the timely improvement of the professional activities of nurses in the Trans-Baikal Territory. It considers the use of operational management tools to improve the work of the front desk (registry), pre-physician  examination rooms. Particular attention is paid to the implementation of the «Health Coordinators» project in the Trans-Baikal Territory.В современном здравоохранении  все бóльшую актуальность приобретают принципы, лежащие в основе пациентоориентированности,  направленные  на сохранение здоровья  пациента,  а также  продуктивное  сотрудничество между медицинским работником и пациентом. В статье представлены результаты своевременного совершенствования профессиональной  деятельности  медицинских сестер Забайкальского  края. Рассматривается применение инструментов операционного менеджмента для улучшения работы регистратуры, кабинетов доврачебного приема. Особое внимание уделено реализации проекта «Координаторы здоровья» на территории Забайкальского края

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to turn the exponentially growing amount of data into knowledge. Here, we provide an overview of SIB's resources and competence areas, with a strong focus on curated databases and SIB's most popular and widely used resources. In particular, SIB's Bioinformatics resource portal ExPASy features over 150 resources, including UniProtKB/Swiss-Prot, ENZYME, PROSITE, neXtProt, STRING, UniCarbKB, SugarBindDB, SwissRegulon, EPD, arrayMap, Bgee, SWISS-MODEL Repository, OMA, OrthoDB and other databases, which are briefly described in this article

Implementation of a patient-focused approach in the work of primary care pediatric nurses of medical organizations of the Trans-Baikal Territory

In modern health care, the principles underlying patient-orientated healthcare, aimed at preserving the health of the patient, as well as the productive cooperation between the medical caregivers and the patient, are becoming increasingly important. The article presents the results of the timely improvement of the professional activities of nurses in the Trans-Baikal Territory. It considers the use of operational management tools to improve the work of the front desk (registry), pre-physician  examination rooms. Particular attention is paid to the implementation of the «Health Coordinators» project in the Trans-Baikal Territory

Altered Monocyte and Lymphocyte Phenotypes Associated with Pathogenesis and Clinical Efficacy of Progestogen Therapy for Peritoneal Endometriosis in Adolescents

Background: Immunological imbalances characteristic of endometriosis may develop as early as the primary manifestations of the disease in adolescence. Objective: To evaluate subpopulation dynamics of monocytes and lymphocytes in peripheral blood and peritoneal fluid of adolescents with peritoneal endometriosis at diagnosis and after 1-year progestogen therapy. Methods: This study included 70 girls, 13–17 years old, diagnosed laparoscopically with peritoneal endometriosis (n = 50, main group) or paramesonephric cysts (n = 20, comparison group). Phenotypes of monocytes and lymphocytes of the blood and macrophages of the peritoneal fluid were analyzed by flow cytometry at diagnosis and during progestogen therapy. Results: Differential blood counts of CD16+ (p + (p = 0.017) monocytes were identified as independent risk factors for peritoneal endometriosis in adolescents. During the treatment, cytotoxic lymphocytes CD56dimCD16bright (p = 0.049) and CD206+ monocytes (p p = 0.017). The CD56dimCD16bright blood counts before (p p = 0.006), as well as CD206+ blood counts during the treatment (p = 0.038), were associated with the efficacy of pain relief after 1-year progestogen therapy. Conclusions: Adolescents with peritoneal endometriosis have altered counts of pro- and anti-inflammatory monocytes and lymphocytes both before and after 1-year progestogen therapy, correlating with treatment efficacy and justifying long-term hormonal therapy