Visual outcomes and higher-order aberrations in eyes implanted with hybrid extended depth of focus intraocular lens

PURPOSE: To study the visual outcomes and higher order aberrations in eyes implanted with Hybrid EDOF IOL, particularly in Indian eyes. MATERIALS AND METHODS: This is retrospective case series where subjects aged between 40-65 years and were implanted with LUCIDIS IOL by single surgeon were included. Subjects with Pre surgery corneal astigmatism > 1.50 D, corneal guttae, IOP >22mmHg, any ocular Co morbidities, Intra or post operative complication were excluded. At 1 month follow up, uncorrected visual acuities at distance (UCDVA), intermediate (UCIVA) and near (UCNVA), refraction were recorded. Internal Higher order aberrations and strehl ratio for a fixed pupil of 4mm and 6mm were calculated using NIDEK OPD Scan. Monocular defocus curve was obtained at 4 meter logMAR chart. RESULTS: Total of 55 eyes of 35 patients with mean±SD age of 58.50±7.49 years were evaluated. 89.09% of the eyes achieved visual acuity of 6/6. 49.09% could read N10 font at intermediate distance without any correction and 85.45% of the eyes had uncorrected near visual acuity of N6. Around 67% of the eyes did not require any refractive correction whereas around 26% of the eyes required correction upto ±0.25D. The defocus curve showed that visual acuity also ranges from 0.05 logMAR to 0.2 logMAR for Plano to -3.00D respectively. Mean±SD Strehl ratio at 4 and 6 mm pupil size was 0.06±0.04 and 0.02±0.02 respectively. CONCLUSION: Hybrid EDOF IOL such as LUCIDIS provides excellent vision at all distances. This could be attributed to IOL design which is spherical aberration neutral lens

Age-related variations in corneal stress-strain index in the Indian population

Purpose: To report age-related variations in corneal stress–strain index (SSI) in healthy Indians. Methods: It was a retrospective study where healthy Indian individuals aged between 11 and 70 years who had undergone corneal biomechanics assessment using Corvis ST between January 2017 and December 2021 were enrolled. Composite corneal biomechanical parameters and corneal SSI were abstracted from Corvis ST and compared across different age groups using one-way analysis of variance (ANOVA). Also, Pearson's correlation was used to evaluate the association between age and SSI. Results: Nine hundred and thirty-six eyes of 936 patients with ages between 11 and 77 years with mean ± SD intraocular pressure (IOP) and pachymetry of 16.52 ± 2.10 mmHg and 541.13 ± 26.39 μs, respectively. Composite corneal biomechanical parameters such as deformation amplitude ratio max at 1 mm (P < 0.001) and 2 mm (P < 0.001), biomechanically corrected IOP (P = 0.004), stiffness parameter at A1 (P < 0.001, Corvis biomechanical index (P < 0.018), and SSI (P < 0.001) were found to be significantly different as a function of age group. We noted a statistically significant positive association of SSI with age (P < 0.001), spherical equivalent refractive error (P < 0.001), and IOP (P < 0.001) and a significant negative association with anterior corneal astigmatism (P < 0.001) and Anterior chamber depth (ACD) (P < 0.001). Also, SSI was positively associated with SPA1 and bIOP, whereas negatively associated with integrated radius, max inverse radius, and Max Deformation amplitude (DA) ratio at 1 mm and 2 mm. Conclusion: We noted a positive association of corneal SSI with age in normal healthy Indian eyes. This information could be helpful for future corneal biomechanical research