Glucose measurement using Surface Enhanced Raman Scattering

Surface Enhanced Raman Scattering (SERS) has a great potential to serve as a monitoring technology for biomolecules, but sensing biomolecules for practical purposes have remained challenging for two reasons. One of the challenges is securing SERS substrates with uniform spatial enhancement that is crucial for quantitative measurements, and the other is finding proper linker molecules that will promote the surface enhancement. To address these challenges, we have been developing a new approach of using highly sensitive surface enhanced Raman scattering (SERS) platform for glucose sensing. In the presentation, I will discuss the fabrication of high performance 3D SERS substrate based on straightforward, two successive wet chemical processes, with experimentally proven strong enhancement and excellent spatial uniformity as well as the use of new linker molecules for making glucose-specific SERS substrates and their use in performing quantitative glucose measurements. Glucose sensing results from different development stages will be discussed

Glucose measurement using Surface Enhanced Raman Scattering

Surface Enhanced Raman Scattering (SERS) has a great potential to serve as a monitoring technology for biomolecules, but sensing biomolecules for practical purposes have remained challenging for two reasons. One of the challenges is securing SERS substrates with uniform spatial enhancement that is crucial for quantitative measurements, and the other is finding proper linker molecules that will promote the surface enhancement. To address these challenges, we have been developing a new approach of using highly sensitive surface enhanced Raman scattering (SERS) platform for glucose sensing. In the presentation, I will discuss the fabrication of high performance 3D SERS substrate based on straightforward, two successive wet chemical processes, with experimentally proven strong enhancement and excellent spatial uniformity as well as the use of new linker molecules for making glucose-specific SERS substrates and their use in performing quantitative glucose measurements. Glucose sensing results from different development stages will be discussed

Examining children in English High Courts with and without implementation of reforms authorized in Section 28 of the Youth Justice and Criminal Evidence Act

This study examined whether the implementation of Section 28 of the Youth Justice and Criminal Evidence Act (1999) improved lawyers' questioning strategies when examining child witnesses in England. The government's Section 28 pilot study involved judges holding Ground Rules Hearings, during which restrictions and limitations were placed on the duration, content, and manner of questions to be asked. Afterwards, children's cross‐examinations were pre‐recorded and later played as part of their evidence at trial. The current study compared cases involving 6‐ to 15‐year‐old alleged victims of sexual abuse in which Section 28 was (n = 43) and was not (n = 44) implemented. Defence lawyers in Section 28 cases asked significantly fewer suggestive questions and more option‐posing questions than defence lawyers in Nonsection 28 cases. Younger children complied more with defence lawyers' suggestive questions. Ground Rules Hearings improved lawyers' questioning strategies, regardless of the case's involvement in the Section 28 pilot study