16,501 research outputs found
Limitations and tradeoffs in synchronization of large-scale networks with uncertain links
We study synchronization in scalar nonlinear systems connected over a linear
network with stochastic uncertainty in their interactions. We provide a
sufficient condition for the synchronization of such network systems expressed
in terms of the parameters of the nonlinear scalar dynamics, the second and
largest eigenvalues of the mean interconnection Laplacian, and the variance of
the stochastic uncertainty. The sufficient condition is independent of network
size thereby making it attractive for verification of synchronization in a
large size network. The main contribution of this paper is to provide
analytical characterization for the interplay of roles played by the internal
dynamics of the nonlinear system, network topology, and uncertainty statistics
in network synchronization. We show there exist important tradeoffs between
these various network parameters necessary to achieve synchronization. We show
for nearest neighbor networks with stochastic uncertainty in interactions there
exists an optimal number of neighbors with maximum margin for synchronization.
This proves in the presence of interaction uncertainty, too many connections
among network components is just as harmful for synchronization as the lack of
connection. We provide an analytical formula for the optimal gain required to
achieve maximum synchronization margin thereby allowing us to compare various
complex network topology for their synchronization property
Re-visiting the One-Time Pad
In 1949, Shannon proved the perfect secrecy of the Vernam cryptographic
system,also popularly known as the One-Time Pad (OTP). Since then, it has been
believed that the perfectly random and uncompressible OTP which is transmitted
needs to have a length equal to the message length for this result to be true.
In this paper, we prove that the length of the transmitted OTP which actually
contains useful information need not be compromised and could be less than the
message length without sacrificing perfect secrecy. We also provide a new
interpretation for the OTP encryption by treating the message bits as making
True/False statements about the pad, which we define as a private-object. We
introduce the paradigm of private-object cryptography where messages are
transmitted by verifying statements about a secret-object. We conclude by
suggesting the use of Formal Axiomatic Systems for investing N bits of secret.Comment: 13 pages, 3 figures, submitted for publication to IndoCrypt 2005
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Health economics of targeted intraoperative radiotherapy (TARGIT-IORT) for early breast cancer: a cost-effectiveness analysis in the United Kingdom
Objective: The clinical effectiveness of targeted intraoperative radiotherapy (TARGIT-IORT) has been confirmed in the randomised TARGIT-A (targeted intraoperative radiotherapy-alone) trial to be similar to a several weeks’ course of whole-breast external-beam radiation therapy (EBRT) in patients with early breast cancer. This study aims to determine the cost effectiveness of TARGIT-IORT to inform policy decisions about its wider implementation. Setting TARGIT-A randomised clinical trial (ISRCTN34086741) which compared TARGIT with traditional EBRT and found similar breast cancer control, particularly when TARGIT was given simultaneously with lumpectomy.
Methods: Cost-utility analysis using decision analytic modelling by a Markov model. A cost-effectiveness Markov model was developed using TreeAge Pro V.2015. The decision analytic model compared two strategies of radiotherapy for breast cancer in a hypothetical cohort of patients with early breast cancer based on the published health state transition probability data from the TARGIT-A trial. Analysis was performed for UK setting and National Health Service (NHS) healthcare payer’s perspective using NHS cost data and treatment outcomes were simulated for both strategies for a time horizon of 10 years. Model health state utilities were drawn from the published literature. Future costs and effects were discounted at the rate of 3.5%. To address uncertainty, one-way and probabilistic sensitivity analyses were performed.
Main outcome measures: Quality-adjusted life-years (QALYs).
Results: In the base case analysis, TARGIT-IORT was a highly cost-effective strategy yielding health gain at a lower cost than its comparator EBRT. Discounted TARGITIORT and EBRT costs for the time horizon of 10 years were ÂŁ12 455 and ÂŁ13 280, respectively. TARGIT-IORT gained 0.18 incremental QALY as the discounted QALYs gained by TARGIT-IORT were 8.15 and by EBRT were 7.97 showing TARGIT-IORT as a dominant strategy over EBRT. Model outputs were robust to one-way and probabilistic sensitivity analyses.
Conclusions: TARGIT-IORT is a dominant strategy over EBRT, being less costly and producing higher QALY gain
Matrix Representation of Iterative Approximate Byzantine Consensus in Directed Graphs
This paper presents a proof of correctness of an iterative approximate
Byzantine consensus (IABC) algorithm for directed graphs. The iterative
algorithm allows fault- free nodes to reach approximate conensus despite the
presence of up to f Byzantine faults. Necessary conditions on the underlying
network graph for the existence of a correct IABC algorithm were shown in our
recent work [15, 16]. [15] also analyzed a specific IABC algorithm and showed
that it performs correctly in any network graph that satisfies the necessary
condition, proving that the necessary condition is also sufficient. In this
paper, we present an alternate proof of correctness of the IABC algorithm,
using a familiar technique based on transition matrices [9, 3, 17, 19].
The key contribution of this paper is to exploit the following observation:
for a given evolution of the state vector corresponding to the state of the
fault-free nodes, many alternate state transition matrices may be chosen to
model that evolution cor- rectly. For a given state evolution, we identify one
approach to suitably "design" the transition matrices so that the standard
tools for proving convergence can be applied to the Byzantine fault-tolerant
algorithm as well. In particular, the transition matrix for each iteration is
designed such that each row of the matrix contains a large enough number of
elements that are bounded away from 0
New Mean Graphs
A graph that admits a Smarandachely super mean m-labeling is called a Smarandachely super m-mean graph, particularly, a mean graph if m = 2. In this paper, some new families of mean graphs are investigated. We prove that the graph obtained by two new operations called mutual duplication of a pair of
vertices each from each copy of cycle Cn as well as mutual duplication of a pair of edges each from each copy of cycle Cn admits mean labeling
Stochastic Stability Analysis of Discrete Time System Using Lyapunov Measure
In this paper, we study the stability problem of a stochastic, nonlinear,
discrete-time system. We introduce a linear transfer operator-based Lyapunov
measure as a new tool for stability verification of stochastic systems. Weaker
set-theoretic notion of almost everywhere stochastic stability is introduced
and verified, using Lyapunov measure-based stochastic stability theorems.
Furthermore, connection between Lyapunov functions, a popular tool for
stochastic stability verification, and Lyapunov measures is established. Using
the duality property between the linear transfer Perron-Frobenius and Koopman
operators, we show the Lyapunov measure and Lyapunov function used for the
verification of stochastic stability are dual to each other. Set-oriented
numerical methods are proposed for the finite dimensional approximation of the
Perron-Frobenius operator; hence, Lyapunov measure is proposed. Stability
results in finite dimensional approximation space are also presented. Finite
dimensional approximation is shown to introduce further weaker notion of
stability referred to as coarse stochastic stability. The results in this paper
extend our earlier work on the use of Lyapunov measures for almost everywhere
stability verification of deterministic dynamical systems ("Lyapunov Measure
for Almost Everywhere Stability", {\it IEEE Trans. on Automatic Control}, Vol.
53, No. 1, Feb. 2008).Comment: Proceedings of American Control Conference, Chicago IL, 201
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