EVALUATION OF ANXIOLYTIC POTENTIAL OF VARIOUS EXTRACTS OF TAMARINDUS INDICA FLOWERS

Objective: The objective of this study was designed to gauge the antianxiety activity of varied extracts, namely, n-hexane, chloroform, ethyl acetate, and methanol of the flowers of Tamarindus indica using elevated plus maze (EPM) model in albino mice. Methods: Coarsely powdered tamarind was powdered and subjected to exhaustive Soxhlet extraction using n-hexane, chloroform, ethyl acetate, and methanol. Solvents were recovered from all extracts using a rotary vacuum evaporator under reduced pressure. Albino mice have ministered orally with different doses of the extracts (i.e., 200 and 400 mg/kg) and behavior was observed on the EPM. The standard (positive control) employed in the study Diazepam (2 mg/kg, P.O). Results: Results indicate that the methanol extract of T. indica flowers showed maximum and significant dose-dependent effect at 200 and 400 mg/kg on EPM, the results were just like the standard antianxiety agent diazepam (2 mg/kg). Locomotor activity evaluated with two different doses of T. indica (200 and 400 mg/kg) using actophotometer. The results were shown to be decreased in a dose dependent model compared to control. Conclusion: The methanol extract shows that the presence of polyphenols could be liable for the anxiolytic potential of T. indica. Hence, this plant could also be used as a useful antianxiety agent

A CASE REPORT ON ISOLATED HEMATURIA WITH ANEMIA DUE TO SCHISTOSOMA HAEMATOBIUM

An unsual case in India was reported with an Isolated Hematuria with Anemia due to Schistosoma Haematobium. A male North African patient aged with 22 years admitted in hospital in Hyderabad with chief complaints of hematuria with dysuria, fever with night sweats and shortness of breath during exercise. His skin appears as pale. His history known that he came to India for his academics. He has a habit of swimming in lake at his country. He has no known past medical history and medication history. His blood reports were found to be low hemoglobin levels and low RBC count. His urine analysis results with reddish colored erythrocytes and crystals with an absence of proteins and casts. Microscopic examination of urine detects Schistosoma Haematobium eggs by using repeated concentration techniques

TAMARINDUS INDICA L. (FABACEAE): EXTENT OF EXPLORED USE IN TRADITIONAL MEDICINE

Tamarind (Tamarindus indica L.) belongs to the family of Fabaceae (Leguminosae), subfamily Caesalpinioideae, is a very important food within the tropics. Medicinal plants are the rear bone of traditional medicine (TM). TM is vital in tropical countries: Contrary to pharmaceuticals, pharmacological, and pharmacotherapy. T. indica is employed as TM in India, Africa, Pakistan, Bangladesh, Nigeria, and most of the tropical countries. It is used traditionally in abdominal pain, diarrhea and dysentery, helminths infections, wound healing, malaria and fever, constipation, inflammation, cell cytotoxicity, gonorrhea, and eye diseases. It is numerous chemical values and is rich in phytochemicals, and hence, the plant is reported to possess antidiabetic activity, antimicrobial activity, antivenomic activity, antioxidant activity, antimalarial activity, hepatoprotective activity, antiasthmatic activity, laxative activity, and antihyperlipidemic activity. Thus, the aim of the present review demonstrates the plant contains in leaves, seeds, roots, pulp, fruits, and flowers an excellent sort of bioactive substances that have beneficial effects on human health and therefore the possibility of application in various tropical, pharmaceutical, and industrial sectors