15 research outputs found
Safety and disease monitoring biomarkers in Duchenne muscular dystrophy: results from a Phase II trial
Get PDFAim: Evaluate the utility of glutamate dehydrogenase (GLDH) and cardiac troponin I as safety biomarkers, and creatine kinase and muscle injury panel as muscle health biomarkers in Duchenne muscular dystrophy. Patients & methods: Data were collected during a Phase II trial of domagrozumab. Results: GLDH was a more specific biomarker for liver injury than alanine aminotransferase. Cardiac troponin I elevations were variable and not sustained, limiting its applicability as a biomarker. Muscle injury panel biomarkers were no more informative than creatine kinase as a muscle health biomarker. Conclusion: Results support the use of GLDH as a specific biomarker for liver injury in patients with Duchenne muscular dystrophy
Differentiation and description of aromatic short grain rice landraces of eastern Indian state of Odisha based on qualitative phenotypic descriptors
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A Menon-type identity concerning Dirichlet characters and a generalization of the gcd function
No full textBis(3,5-diiodo-2,4,6-trihydroxyphenyl)squaraine photodynamic therapy disrupts redox homeostasis and induce mitochondria-mediated apoptosis in human breast cancer cells
No full textPrevalence of indicator and potential pathogenic bacterial groups in the Chapora bay-estuarine system, Goa, central west coast of India
No full textFuzzy clustering and Whale-based neural network to food recognition and calorie estimation for daily dietary assessment
No full textLigand-Mediated and Copper-Catalyzed C(sp3)-H Bond Functionalization of Aryl Ketones with Sodium Sulfinates under Mild Conditions
No full textFast simultaneous assessment of renal and liver function using polymethine dyes in animal models of chronic and acute organ injury
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