20 research outputs found
Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation
Full text linkAnthocyanins encapsulated by PLGA@PEG nanoparticles potentially improved its free radical scavenging capabilities via p38/JNK pathway against Aβ1–42-induced oxidative stress
Full text linkRecent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy
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PLGA encapsulation effect on Bioquin-HMPAO: radiolabeling and in vitro behaviour on brain and lung cancer cells
No full textWOS: 000383579900016Bioquin-HMPAO (BH) was previously investigated as a novel brain imaging agent by in vivo biodistribution studies. Present studies are carried out to explore radiolabeling and in vitro behaviour evaluation of poly (lactic-co-glycolic acid) (PLGA) encapsulated BH nanocapsules (BH-PLGA NCs). BH-PLGA NCs were characterized utilizing dynamic light scattering and scanning electron microscope. Encapsulation effect on radiolabeling with Tc-99m was examined by stability and lipophilicity studies and effect on in vitro behaviour of Tc-99m-BH was evaluated by incorporation studies on DAOY, U87-MG and A549 cells. It is observed that PLGA encapsulation has a positive and reinforcement effect.Ege University Research FundEge University [2011 NBE 003]Current work is supported by Ege University Research Fund (contract no 2011 NBE 003). The authors thank to Cansu Uzaras and Cigdem Ichedef for the technical assistance during the assays
PLGA encapsulation effect on Bioquin-HMPAO: radiolabeling and in vitro behaviour on brain and lung cancer cells
No full textEvaluation of the antibacterial activity of poly-(d,l-lactide-co-glycolide) nanoparticles containing violacein
No full textPLGA encapsulation and radioiodination of indole-3-carbinol: investigation of anticancerogenic effects against MCF7, Caco2 and PC3 cells by in vitro assays
No full textVentilatory Chemosensory Drive Is Blunted in the mdx Mouse Model of Duchenne Muscular Dystrophy (DMD)
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