7 research outputs found
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2021
- Field of study
Caveolae are spherically shaped nanodomains of the plasma membrane, generated by cooperative assembly of caveolin and cavin proteins. Cavins are cytosolic peripheral membrane proteins with negatively charged intrinsically disordered regions that flank positively charged α-helical regions. Here, we show that the three disordered domains of Cavin1 are essential for caveola formation and dynamic trafficking of caveolae. Electrostatic interactions between disordered regions and α-helical regions promote liquid-liquid phase separation behaviour of Cavin1 in vitro, assembly of Cavin1 oligomers in solution, generation of membrane curvature, association with caveolin-1, and Cavin1 recruitment to caveolae in cells. Removal of the first disordered region causes irreversible gel formation in vitro and results in aberrant caveola trafficking through the endosomal system. We propose a model for caveola assembly whereby fuzzy electrostatic interactions between Cavin1 and caveolin-1 proteins, combined with membrane lipid interactions, are required to generate membrane curvature and a metastable caveola coat
Live confocal imaging of zebrafish notochord cells under mechanical stress in vivo
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
The zebrafish is a vertebrate model suited to the exploration of cell biology within a whole organism. Hypotheses in cell mechanics can be tested by using the zebrafish notochord as a manipulable experimental system. Here, the methodologies to prepare, label, and simultaneously induce and image mechanical loading on live zebrafish notochord cells via electrical stimulation are described. This approach investigates membrane mechanics in a live, physiological setting and is thus suited for caveola research where observations within the tissues of an intact organism are increasingly relevant. This chapter also aims to introduce fundamental methodologies for the use of zebrafish in “in vivo cell biology.
Photometrische Methoden
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- U. K. A. E. A.
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- V Camera
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- VA Unkovskaya
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1972
- Field of study
Scandium, Yttrium und die Elemente der seltenen Erden, Röntgenspektralanalyse
- Author
- A Barbieri
- A Barbieri
- A Bbukl
- A Bbukl
- A Bommer
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- A Claassen
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- A Hennings
- A Jandelli
- A Jewsbury
- A Job
- A Job
- A Job
- A Kolb
- A Kvalheim
- A Langlet
- A Loose
- A Malaguti
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- A Malaguti
- A Malaguti
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- A Purushottam
- A Purushottam
- A Rosenheim
- A Seitz
- A Waegner
- A Waegner
- A Welsbach v.
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- A Welsbach v.
- A Welsbach v.
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- A Welsbach v.
- A Wöber
- A Zalkin
- AC Neish
- AC Rise
- AE Boss
- AE Pavlish
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- AF Clifford
- AF Williams
- AJ Freedman
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- AJ Medalia
- AJ Popov
- AJ Popov
- AM Ismail
- AP Wills
- AR Eberle
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- AR Eberle
- B Borelli
- B Brauner
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- B Brauner
- B Brauner
- B Brauner
- B Brauner
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- B Brauner
- B Brauner
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- B Brauner
- B Brauner
- B Brauner
- B Cabrera
- B Goldschmidt
- B Lange
- B Raghava Rao
- B Raghava Rao
- BH Eswaranarayana
- BH Ketelle
- BH Kettele
- BL Vallee
- BS Evans
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- BS Hopkins
- C Auer Welsbach v.
- C Benedicks
- C Delaunay
- C Duval
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- C Feldman
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- M Fred
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- M Pattison
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- M Servigne
- M Servigne
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- M Servigne
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- M Trombe
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- M Venkataramaniah
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- M Venkataramaniah
- M Venkataramaniah
- M Wunder
- MH Klaproth
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- O Boudouabd
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- O Erämetsä
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- O Hahn
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- O Hauser
- O Hauser
- O Ruff
- O Tomicek
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- ON Witt
- OS Plantinga
- P Albert
- P Jannasch
- P Mengel
- P Mengel
- P Nicolardot
- P Nicolardot
- P Radhakrishna
- P Schützenberger
- P Schützenberger
- P Spacu
- P Spacu
- P Urbain
- P Urbain
- P Wenger
- P Wenger
- PC Banerjee
- PC Banerjee
- PE Browning
- PE Browning
- PE Browning
- PE Browning
- PE Browning
- PH Brinton
- PHM-P Brinton
- PHM-P Brinton
- Pratt
- PS Murty
- PW Selwood
- PW Selwood
- PW Selwood
- PW Selwood
- R Berg
- R Berg
- R Berg
- R Berg
- R Bock
- R Bock
- R Bunsen
- R Bunsen
- R Bunsen
- R Chavastelon
- R Fresenius
- R Glocker
- R Glocker
- R Glocker
- R Hutgren
- R Janssens
- R Janssens
- R Kunin
- R Ladenbtjrg
- R Lakshmana Rao
- R Lakshmana Rao
- R Lang
- R Lang
- R Lessnig
- R Lessnig
- R Lindner
- R Lindner
- R Lindner
- R Lindner
- R Mannkopff
- R Marc
- R Marc
- R Mavrodineanu
- R Pribil
- R Pribil
- R Pribil
- R Pribil
- R Rasin-Streden
- R Rasin-Streden
- R Rasin-Streden
- R Uzel
- R Vogel
- R-L Espil
- RA Papucci
- RA Wells
- RB Moore
- RB Moore
- RB Moore
- RC Benner
- RC Hirt
- RC Hirt
- RC Vickery
- RC Vickery
- RC Wells
- RC Wells
- RC Wells
- RD Hall
- RE Meyers
- RG Name van
- RG Russell
- RH Heidel
- RH Steinberg
- RJ Carney
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RJ Meyer
- RW Ball
- RW Ball
- RW Rinehardt
- S Jordan
- S Levy
- S Mayer
- S Mayer
- S Mayer
- S Merkader
- S Misumi
- S Misumi
- S Misumi
- S Misumi
- S Misumi
- S Misumi
- S Misumi
- S Misumi
- Sarver
- SJ Johnstone
- SJ Johnstone
- SJ Johnstone
- SJ Johnstone
- SJ Johnstone
- SJ Malow
- SJ Malow
- SK Datta
- SK Datta
- SK Datta
- SK Datta
- SM Jörgensen
- Smith
- SN Murthy
- Spencer
- T Dupuis
- T Dupuis
- T Dupuis
- T Dupuis
- T Inoue
- T Inoue
- T Inoue
- T Lindeman
- T Lindeman
- T Moelleb
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Moeller
- T Postius
- TA Rafter
- TA Usspenskaja
- TA Usspenskaja
- TG Sahama
- THI Pirtea
- THI Pirtea
- TKS Murthy
- TKS Murthy
- TL Pirtea
- TO Smith
- TO Smith
- TO Smith
- TP McCutcheon
- TV Suryanarayana
- TV Suryanarayana
- TW Biedermann
- TW Newton
- U Dehlinger
- V Gilpin
- V Hovorka
- V Lehner
- V Lenher
- V Sastry
- VA Fassel
- VA Fassel
- VA Fassel
- VA Fassel
- VA Fassel
- VK Iya
- VK Iya
- VM Goldschmidt
- VM Goldschmidt
- VM Protopopov
- VV Bogdanova
- VV Bogdanova
- W Biltz
- W Biltz
- W Biltz
- W Biltz
- W Biltz
- W Biltz
- W Biltz
- W Bothe
- W Busch
- W Busch
- W Feit
- W Feit
- W Feit
- W Feit
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Fischer
- W Gerlach
- W Gerlach
- W Gibbs
- W Gibbs
- W Gibbs
- W Gibbs
- W Gibbs
- W Gibbs
- W Gibbs
- W Gibbs
- W Hisinger
- W Kapfenberger
- W Klemm
- W Klemm
- W Klemm
- W Meggers
- W Meggers
- W Muthmann
- W Muthmann
- W Muthmann
- W Muthmann
- W Noddack
- W Noddack
- W Pbandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Prandtl
- W Ryan
- W Schröder
- W Schröder
- W Westwood
- W Wild
- WA Brooksbank
- WA Drushel
- WB Giles
- WB Hicks
- WC Baumann
- WD Cooke
- WD Treadwell
- WF Hillebrand
- WF Meggers
- WF Meggers
- WF Meggers
- WF Meggers
- WF Meggers
- WG Schtscherbakow
- WG Schtscherbakow
- WM Spicer
- WR Schoelker
- WR Schoeller
- WR Schoeller
- WW Meinke
- Wöhler
- Y Cauchois
- Z Hagiwaba
- Z Hagiwaba
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1956
- Field of study
Anatomical and Physiological Factors Contributing to Chronic Muscle Pain
- Author
- A Messeguer
- A Nakao
- AE Kindig
- AR Light
- B Diehl
- B Saltin
- B Zhong
- BE Cairns
- C Malm
- C Wang
- C Wu
- C Zhang
- C-CJ Lin
- CA Parada
- CC Chen
- CJ Woolf
- D Dessem
- D Tillu
- DA Skyba
- DA Skyba
- DB Reichling
- DB Reichling
- DC Immke
- DC Molliver
- DP Green
- DPC Lloyd
- E Deval
- E Lingueglia
- E Vázquez-Delgado
- EA Dannecker
- EE Castrillon
- FC Meotti
- FC Prado
- G Hathway
- G Sacchetti
- G-Y Xu
- GA Brooks
- GR Lewin
- H Mebane
- H Miranda
- H Mørk
- H Ota
- H Urai
- H Valkeinen
- HC Hertel
- HJ Strausbaugh
- I Proost De
- J Bangsbo
- J Li
- J Li
- J Li
- J Li
- J Reinöhl
- J Sakurai
- J Xing
- J Xing
- JA Faulkner
- JA Verbunt
- JB Calixto
- JD Greenspan
- JG Pickar
- JG Tidball
- JK Eibl
- JM Teixeira
- JM Thompson
- JP Shah
- JX Wu
- JY Ro
- JY Ro
- K Ahacic
- K Kawakita
- K Kobayashi
- K Matsumoto
- KA Keay
- KA Sluka
- KA Sluka
- KA Sluka
- KA Sluka
- KD Kniffki
- KD Kniffki
- KO Aley
- L-J Ling
- LA Frey Law
- LF Azevedo
- LF Silva Da
- LFS Silva Da
- M Chacur
- M Connor
- M Diers
- M Ernberg
- M Gautam
- M Ikeuchi
- M Karamouzis
- M Martinez-Lavin
- M Prasad
- M Shinoda
- M Shinoda
- M Tominaga
- M Tsukagoshi
- M-Y Min
- MA Cimmino
- MC Uchida
- MCG Oliveira
- ME Barabas
- MJ Stacey
- MKH Bement
- MP Jankowski
- MV Chao
- N Ito
- N-I-H Syed
- NJ Spencer
- NS Gregory
- OA Dina
- OA Dina
- OA Dina
- P Alvarez
- P Honore
- P Mease
- P Svensson
- PG Green
- PV Lishko
- R Ambalavanar
- R Inoue
- R Peyron
- R Radhakrishnan
- R Rukwied
- R Staud
- R Staud
- R Staud
- R Waldmann
- R Waldmann
- R Waldmann
- R Wang
- RD Foreman
- RL Hanna
- RM Bennett
- RY Walder
- RY Walder
- RY Walder
- S Delliaux
- S Mense
- S Mense
- S Mense
- S Murase
- S-J Cheng
- SG Khasar
- SG Khasar
- SG Khasar
- SG Khasar
- SG Khasar
- SG Khasar
- SR Han
- T Kumazawa
- T Moriyama
- T Nasu
- T Schmidt-Wilcke
- T Taguchi
- T Yokoyama
- TB Hucho
- TJ Coderre
- TJ Coderre
- TKY Kaan
- TW Sherwood
- U Hoheisel
- U Hoheisel
- U Hoheisel
- U Proske
- V Martin
- VA Campanucci
- VP Zagorodnyuk
- W Gibson
- W-K Chen
- WT Birdsong
- XW Fu
- Y Fujii
- Y Ji
- Y Sun
- Y Wang
- YX Wang
- Z Gao
- Z Luo
- Z Wu
- Z Xiang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Zika Virus as an Emerging Neuropathogen: Mechanisms of Neurovirulence and Neuro-Immune Interactions
- Author
- A Alimov
- A Grant
- A Hamzaoui
- A Mithal
- A Rolls
- A Rostami
- A Waschbisch
- AA Babcock
- AA Leis
- AA Moura da Silva
- AD Haddow
- AE Lin
- AJ Barkovich
- AJ Rolfe
- AK Gupta
- AM Butt
- André F. Carvalho
- AS Oliveira Melo
- AT Reder
- B Barak
- B Miranda-Filho Dde
- B Parra
- B Shrestha
- B van den Berg
- B van den Berg
- BD Clarke
- BR Wakerley
- BR Wakerley
- Brendon Stubbs
- C Lazarus
- C Li
- C Martinez
- CA Moore
- CB Coyne
- CC Tam
- CF Lin
- CG Woods
- CG Woods
- CJ Lai
- CL Frank
- CM Caporale
- CM Forrest
- CM Lange
- Cristiano A. Köhler
- CV Ventura
- CW Ang
- CW Ang
- D Abuelo
- D Ebrahimi-Fakhari
- D Fisher
- D Gatherer
- D Golan
- D Kaul
- D Luo
- D Paul
- D Sang
- D Sirohi
- D Tappe
- DA Muller
- DL Akey
- DL Akey
- DM Klinman
- DR O'Leary
- DS Asnis
- DS Macedo
- DS Monos
- DW Macfarlane
- E D'Ortenzio
- E Lee
- E Oehler
- E Okun
- E Okun
- E Petersen
- E Simon-Loriere
- EB Hayes
- EE Magira
- EG Acosta
- ER Oliveira
- ES Coro
- ES Paixao
- ES Sotirchos
- F Costa
- F Zhang
- FN Macnamara
- G Calvet
- G Falivelli
- G Kuno
- G Moratorio
- Gerwyn Morris
- GW Dick
- GW Dick
- H Amin
- H Dong
- H Jiao
- H Li
- H Tang
- H Tillu
- HH Ho
- HJ Cheng
- HJ Cheng
- HJ Willison
- HJ Willison
- HL Zhang
- HM Lazear
- I Nachamkin
- II Bogoch
- IJ Liu
- IR Muylaert
- J Ashour
- J Dang
- J Flipse
- J Junjhon
- J Kraus
- J Mlakar
- J Rocklov
- J-B Brault
- J-M Anaya
- JA Mondotte
- JA Roby
- JA Roby
- JB Courcet
- JB Plotkin
- JC Saiz
- JD Godin
- JF Chan
- JG Leroy
- JH Amorim
- JJ Chua
- JJ Miner
- JL Muñoz-Jordán
- JR Corona-Rivera
- JT Guo
- JY Leung
- K Kawada
- K Lühn
- K Maringer
- K Yaddanapudi
- KD Yamaguchi
- KJ Lubick
- KK Nyati
- KO Poropatich
- L Bavia
- L Bornsen
- L De Giglio
- L Durelli
- L Gabis
- L Miorin
- L Watrin
- LA Shackelton
- LY Wu
- M Beltramello
- M Chen
- M Halliday
- M Lafon
- M May
- M Muller
- M Rastogi
- M Sironi
- M von der Hagen
- MA Brinton
- MA Edeling
- MA Kutzler
- MA Martin-Acebes
- MC Boersma
- MC Dalakas
- MC Whiteman
- MD Fernandez-Garcia
- ME Dourado
- Michael Maes
- MM Alen
- MO Lu
- MR Duffy
- N Berthet
- N Fekih-Mrissa
- N Mimura
- N Wikan
- N Yuki
- NL Bayless
- O Faye
- P Avirutnan
- P Boeuf
- P Ejlerskov
- P Palmeira
- PA van Doorn
- PC Godschalk
- PF Zipfel
- PP Garcez
- PP Jin
- R de Alwis
- R Hamel
- RC Vannucci
- RI Nurieva
- RJ Kahoud
- RJ Kuhn
- RS Houliston
- RS Lanciotti
- RW Driggers
- S Aguirre
- S Cauchemez
- S Flingai
- S Ioos
- S Kivity
- S Kusunoki
- S Laguesse
- S Lakatosova
- S Martinez
- S Mukhopadhyay
- S Park
- S Parlato
- S Shoji-Kawata
- S Sinha
- S Sukupolvi-Petty
- SA Rasmussen
- SA Skull
- SB Boppana
- SC Tang
- SL Liang
- SM Best
- SM Villordo
- SR Lambert
- SZ Shah
- T Hershey
- T Ishikawa
- T Kolter
- T Kurosu
- T Sasaki
- Tatiana Barichello
- TJ Harris
- TM Bell
- U Kalinke
- V Borrell
- VA Kostyuchenko
- VJ Klema
- VM Cao-Lormeau
- VM Cao-Lormeau
- VS Ramgolam
- W Bueter
- W Dejnirattisai
- W Scheper
- WC Brown
- WJ Liu
- WJ Liu
- WL van der Pol
- WT Hancock
- X Duan
- X Feng
- X Qian
- X Tang
- X Wu
- X Zhang
- X Zhang
- X Zhang
- Y Ma
- Y Tao
- Y Tao
- YC Chuang
- YC Chuang
- YL Lin
- YS Lin
- Z Babaloo
- Z Islam
- Z Zhu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study