Circuit-based interrogation of sleep control.

Sleep is a fundamental biological process observed widely in the animal kingdom, but the neural circuits generating sleep remain poorly understood. Understanding the brain mechanisms controlling sleep requires the identification of key neurons in the control circuits and mapping of their synaptic connections. Technical innovations over the past decade have greatly facilitated dissection of the sleep circuits. This has set the stage for understanding how a variety of environmental and physiological factors influence sleep. The ability to initiate and terminate sleep on command will also help us to elucidate its functions within and beyond the brain

The New Zealand gravimetric quasigeoid model 2017 that incorporates nationwide airborne gravimetry

A one arc-minute resolution gravimetric quasigeoid model has been computed for New Zealand, covering the region (Formula presented.)–(Formula presented.) and (Formula presented.)–(Formula presented.). It was calculated by Wong and Gore modified Stokes integration using the remove–compute–restore technique with the EIGEN-6C4 global gravity model as the reference field. The gridded gravity data used for the computation consisted of 40,677 land gravity observations, satellite altimetry-derived marine gravity anomalies, historical shipborne marine gravity observations and, importantly, approximately one million new airborne gravity observations. The airborne data were collected with the specific intention of reinforcing the shortcomings of the existing data in areas of rough topography inaccessible to land gravimetry and in coastal areas where shipborne gravimetry cannot be collected and altimeter-derived gravity anomalies are generally poor. The new quasigeoid has a nominal precision of (Formula presented.) on comparison with GPS-levelling data, which is approximately (Formula presented.) less than its predecessor NZGeoid09

Resistance exercise training during pregnancy and newborn's birth size: a randomised controlled trial

Objective: Design: Subjects: Results: Conclusion: We examined the effect of light intensity resistance exercise training performed during the second and third trimester of pregnancy on the newborn's birth size. We also studied the association between maternal body weight prior to pregnancy and newborn's birth size.Randomised controlled trial.We randomly assigned 160 sedentary gravidae to either a training (n=80) or a control (n=80) group. The training programme focused on light resistance and toning exercises (three times per week, 35-40 min per session). We recorded the Apgar score, birth weight, birth length, and head circumference of the newborn, as well as gestational age at time of delivery from hospital perinatal records. We also measured maternal weight and height before parity and gestational weight gain.Maternal characteristics neither differed between groups (all P>0.1) nor newborn characteristics (all P>0.1). Maternal body weight was positively and significantly associated with newborn's birth weight and length only in the control group (beta=19.20 and 0.065, respectively, P<0.01).Light intensity resistance training performed over the second and third trimester of pregnancy does not have a negative impact on the newborn's body size or overall health. Exercise interventions might attenuate the adverse consequences of maternal body weight before pregnancy on the newborn's birth size.4.343 JCR (2009) Q1, 23/105 Endocrinology & metabolism, 4/66 Nutrition & dieteticsUE