Beam halo dynamics and control with hollow electron beams

Experimental measurements of beam halo diffusion dynamics with collimator scans are reviewed. The concept of halo control with a hollow electron beam collimator, its demonstration at the Tevatron, and its possible applications at the LHC are discussed.Comment: 5 pages, 4 figures, in Proceedings of the 52nd ICFA Advanced Beam Dynamics Workshop on High-Intensity and High-Brightness Hadron Beams (HB2012), Beijing, China, 17-21 September 201

Actual Issues of Ischemic and Hemorrhagic Events Risk Management During Antithrombotic Therapy in Patients with Acute Coronary Syndrome

Today, optimal duration of double antiplatelet (DAPT) and triple antithrombotic therapy (TATT) in patients with acute coronary syndrome (ACS) remains the subject of scientific and practical discussion on possibilities of ischemic and hemorrhagic risks assessment. Good clinical risk metrics is based on validated risk scales. However, actual clinical guidelines do not provide a universal and generally accepted scale for assessing the balance of risks of ischemic events and bleeding. Is very necessary to determine the optimal content and DAPT or TATT duration is the existence of validated risk assessment scales would allow to optimize the accuracy of risk assessment of ischemic and hemorrhagic events in patients after ACS. One of the probable reasons is absence of validation of existing scales for each specific population of patients with ACS. In this regard, the use of «new» risk assessment systems: PRECISE DAPT and DAPT, in addition to the routine risk assessment scales (GRACE, CRUSADE), could become optimal in all ACS patient categories. In order to identify the initial risk of community-acquired hemorrhagic events during the first 12 months all patients with ACS at the inpatient stage of treatment is used the PRECISE DAPT score. In order to determine the need for prolongation of the standard DAPT. It should be used after 12 months of receiving DAPT in survivors of ACS patients without ischemic events, must be used the DAPT score

Observation of narrow baryon resonance decaying into pKs0pK^0_s in pA-interactions at 70GeV/c70 GeV/c with SVD-2 setup

SVD-2 experiment data have been analyzed to search for an exotic baryon state, the $\Theta^+$-baryon, in a $pK^0_s$ decay mode at $70 GeV/c$ on IHEP accelerator. The reaction $pA \to pK^0_s+X$ with a limited multiplicity was used in the analysis. The $pK^0_s$ invariant mass spectrum shows a resonant structure with $M=1526\pm3(stat.)\pm 3(syst.) MeV/c^2$ and $\Gamma < 24 MeV/c^2$. The statistical significance of this peak was estimated to be of $5.6 \sigma$. The mass and width of the resonance is compatible with the recently reported $\Theta^+$- baryon with positive strangeness which was predicted as an exotic pentaquark ($uudd\bar{s}$) baryon state. The total cross section for $\Theta^+$ production in pN-interactions for $X_F\ge 0$ was estimated to be $(30\div120) \mu b$ and no essential deviation from A-dependence for inelastic events $(\sim A^{0.7})$ was found.Comment: 8 pages, 7 figures, To be submitted to Yadernaya Fizika. v3-v5 - Some references added, minor typos correcte

Origin of elemental carbon in snow from western Siberia and northwestern European Russia during winter-spring 2014, 2015 and 2016

Short-lived climate forcers have been proven important both for the climate and human health. In particular, black carbon (BC) is an important climate forcer both as an aerosol and when deposited on snow and ice surface because of its strong light absorption. This paper presents measurements of elemental carbon (EC; a measurement-based definition of BC) in snow collected from western Siberia and northwestern European Russia during 2014, 2015 and 2016. The Russian Arctic is of great interest to the scientific community due to the large uncertainty of emission sources there. We have determined the major contributing sources of BC in snow in western Siberia and northwestern European Russia using a Lagrangian atmospheric transport model. For the first time, we use a recently developed feature that calculates deposition in backward (so-called retroplume) simulations allowing estimation of the specific locations of sources that contribute to the deposited mass

"m=1" coatings for neutron guides

A substantial fraction of the price for a supermirror neutron guide system is the shielding, which is needed because of the gamma radiation produced as a result of neutron absorption in the supermirror layers. Traditional coatings have been made of nickel-titanium heterostructures, but Ni and Ti also have a fairly high absorption cross section for cold and thermal neutrons. We examine a number of alternatives to Ni as part of a study to reduce the gamma radiation from neutron guides. Materials such as diamond and Be have higher neutron scattering density than Ni, smaller absorption cross section, and when a neutron is absorbed they emit gamma photons with lower energies. We present reflectivity data comparing Ni with Be and preliminary results from diamond coatings showing there use as neutron guide coatings. Calculations show that Be and diamond coatings emit two orders of magnitude fewer gamma photons compared to Ni, mainly because of the lower absorption cross section

"m=1" coatings for neutron guides

A substantial fraction of the price for a supermirror neutron guide system is the shielding, which is needed because of the gamma radiation produced as a result of neutron absorption in the supermirror layers. Traditional coatings have been made of nickel-titanium heterostructures, but Ni and Ti also have a fairly high absorption cross section for cold and thermal neutrons. We examine a number of alternatives to Ni as part of a study to reduce the gamma radiation from neutron guides. Materials such as diamond and Be have higher neutron scattering density than Ni, smaller absorption cross section, and when a neutron is absorbed they emit gamma photons with lower energies. We present reflectivity data comparing Ni with Be and preliminary results from diamond coatings showing there use as neutron guide coatings. Calculations show that Be and diamond coatings emit two orders of magnitude fewer gamma photons compared to Ni, mainly because of the lower absorption cross section

Клинико-экономический анализ эффективности применения левофлоксацина (Таваник) у больных с внебольничной пневмонией

This study was devoted to comparative clinical-and-economical analysis of levofloxacin and ceftriaxone/cefuroxime axetyl for treatment of community-acquired pneumonia. The study was based on results of the opened multi-center comparative randomized clinical trial of T.M.File, J.Sergeti, R. Player et al. (1997) which had demonstrated a statistically significant difference in the antibiotic effectiveness at the 5th to 7th days of the therapy. A sensitivity of the model to the cost range and to a potential rate variability of different administering of the drugs was also investigated.The final analysis of the antibiotics efficacy involved 226 patients treated with levofloxacin and 230 ones received ceftriaxone/cefuroxime axetyl. The therapy was clinically sufficient to the 5th-7th day in 96% of the patients treated with levofloxacin and 90% patients received ceftriaxone/cefuroxime axetyl (the 95% confidence interval was 10.7 to 1.3%). According to our results Tavanic was more benefit compared with the Rocephin/Zinnat mode as it was more effective and less expensive.The conclusive results regarding the economic benefit of levofloxacin requires further clinical and economical trials to compare levofloxacin with other domestic modes for the therapy of the community-acquired pneumonia.Настоящая работа посвящена сравнительному клинико-экономическому анализу применения левофлоксацина и цефтриаксона/цефуроксим аксетила для лечения внебольничной пневмонии. В основу работы положены данные мультицентрового открытого сравнительного рандомизированного клинического исследования T.M.File, J.Sergeti, R.Player и соавт. (1997), где были продемонстрированы статистически значимые различия в эффективности исследуемых антибиотиков на 5-7-й день от начала лечения. Также изучалась чувствительность модели к колебаниям цен на лекарственные средства и к возможным изменениям частоты разных способов введения антибиотиков.Окончательный анализ эффективности антибиотиков проводился на 226 пациентах, получавших левофлоксацин, и 230, получавших цефтриаксон/цефуроксим аксетил. Доля больных, лечение которых было признано клинически эффективным на 5-7-е сутки от начала лечения, составила 96% в группе леченных левофлоксацином и 90% — цефтриаксоном/цефуроксимом аксетилом (95% доверительный интервал различий от 10,7 до 1,3%). Согласно полученным результатам, назначение таваника при внебольничной пневмонии является более целесообразным, чем схемы роцефин/зиннат, поскольку он отличается более высокой эффективностью и меньшими затратами на антибиотикотерапию.Для вынесения окончательного заключения об экономической целесообразности применения левофлоксацина необходимы дальнейшие клинико-экономические исследования, позволяющие сопоставить левофлоксацин с другими схемами, использующимися в отечественных условиях для лечения внебольничной пневмонии

A Quasi-Model-Independent Search for New Physics at Large Transverse Momentum

We apply a quasi-model-independent strategy ("Sleuth") to search for new high p_T physics in approximately 100 pb^-1 of ppbar collisions at sqrt(s) = 1.8 TeV collected by the DZero experiment during 1992-1996 at the Fermilab Tevatron. Over thirty-two e mu X, W+jets-like, Z+jets-like, and 3(lepton/photon)X exclusive final states are systematically analyzed for hints of physics beyond the standard model. Simultaneous sensitivity to a variety of models predicting new phenomena at the electroweak scale is demonstrated by testing the method on a particular signature in each set of final states. No evidence of new high p_T physics is observed in the course of this search, and we find that 89% of an ensemble of hypothetical similar experimental runs would have produced a final state with a candidate signal more interesting than the most interesting observed in these data.Comment: 28 pages, 17 figures. Submitted to Physical Review

Probing BFKL Dynamics in the Dijet Cross Section at Large Rapidity Intervals in ppbar Collisions at sqrt{s}=1800 and 630 GeV

Inclusive dijet production at large pseudorapidity intervals (delta_eta) between the two jets has been suggested as a regime for observing BFKL dynamics. We have measured the dijet cross section for large delta_eta in ppbar collisions at sqrt{s}=1800 and 630 GeV using the DO detector. The partonic cross section increases strongly with the size of delta_eta. The observed growth is even stronger than expected on the basis of BFKL resummation in the leading logarithmic approximation. The growth of the partonic cross section can be accommodated with an effective BFKL intercept of a_{BFKL}(20GeV)=1.65+/-0.07.Comment: Published in Physical Review Letter