Electroneuronomiographical testing of the nictating reflex at patients with senile entropion of a lower eyelid

Purpose. То estimate parameters of the nictating reflex (NR) at patients with senile athonical enthropion a lower eyelid before and after surgical treatment Methods. 25 patients with senile athonical entropion of a lower eyelid OD of the third degree before and for 8-10 days after plastics of a lower eyelid by the deapithelious a skin-muscular rag are surveyed. Research of the NR is led on the device ‘N euro-M VP-4" by a standard technique with registration of the latent time of the components R1 and R2 on the party of stimulation, latent time of the component R2 on the opposite party and definition of type of the component R2 by R.A.Jakupova's classification (2002) Results. At stimulation n.supraorbitalis on the party of operation latentness of tJie component R2 ipsylaterally after operation has authentically decreased from 42,133 to 31,663 мс (p is less than 0,05). At stimulation n.supraorbitalis on the unoperated party also has authentically decreased latentness component R2 ipsylaterally (from 44,5 мс before operation to 32,575 мс after operation, (p is less than 0,05). It testifies to normalization of speed of carrying out of an impulse in system trigeminal-obverse nerves after surgical treatment senile athonical entropion a lower eyelid. Research of qualitative characteristics NR have shown, that after surgical treatment senile entropion of a lower eyelid OD decrease in quantity of cases hyperexitable (on 16%) types NR is observed, at ist simultaneous increase normally excitable types (on 36%). Conclusions. NR can be inportant neurophysiological the test at an estimation of a functional condition of a trunk, bayal kerners and cortical departments of the central nervous system with the purpose of optimization, of methods of surgical treatment of senile dispositions the eyelids.Цель: оценить параметры мигательного рефлекса (МГ) у пациентов с сенильным атоническим знтропионом нижнего века до и после хирургического лечения. Методы: обследованы 25 пациентов с сенильным атоническим знтропионом нижнего века 0D 3 степени до и на 8-10 сутки после пластики нижнего века деэпителизированным кожно-мышечным лоскутом. Исследование МР проведено на аппарате «Нейро-МВП-4» по стандартной методике с регистрацией латентного времени компонентов R1 и R2 на стороне стимуляции, латентного времени компонента R2 на противоположной стороне и определение типа компонента R2 по классификации Р. А. Якупова (2002). Результаты: при стимуляции n.supraorbitalis на стороне операции латентность компонента R2 ипсилатерально после операции достоверно уменьшилась- с 42,133 до 31,663 мс (р<0,05). При стимуляции n.supraorbitalis на не оперированной стороне также достоверно уменьшилась латентность компонента R2 ипсилатерально (с 44,5 мс до операции до 32,575 мс после операции, р<0.05). Что свидетельствует о нормализации скорости проведения импульса в системе тройничный-лицевой нервы после хирургического лечения сенильного атонического энтропиона нижнего века. Исследование качественных характеристик МР показали, что после хирургического лечения сенильного энтропиона нижнего века OD наблюдается снижение количества случаев гипервозбудимых (на 12%), гиперсинхронных (на 8% ), гиповозбудимых (на 16%) типов МР, при одновременном возрастании его нормовозбудимых типов (на36%). Выводы: МР может являться важным нейрофизиологическим тестом при оценке функционального состояния ствола, базальных ядер и корковых отделов ЦНС с целью оптимизации методов хирургического лечения сенильных дислокаций век

Inclusive meson production in peripheral collisions of ultrarelativistic heavy ions

There exist several proposals to use Weizs\"{a}cker-Williams photons generated by ultrarelativistic heavy ions to produce exotic particles in $\gamma\gamma$ fusion reactions. To estimate the background conditions for such reactions we analyze various mechanisms of meson production in very peripheral collisions of ultrarelativistic heavy ions at RHIC and LHC energies. Besides $\gamma\gamma$ fusion they include also electromagnetic $\gamma A$ interactions and strong nucleon-nucleon interactions in grazing $AA$ collisions. All these processes are characterised by low multiplicities of produced particles. $\gamma A$ and $AA$ events are simulated by corresponding Monte Carlo codes, RELDIS and FRITIOF. In each of these processes a certain fraction of pions is produced close to the mid-rapidity region that gives a background for the $\gamma\gamma$ events. The possibility of selecting mesons produced in $\gamma\gamma$ fusion events via different $p_t$ cut procedures is demonstrated.Comment: 27 pages with 4 eps-figures included, uses axodraw.sty Tab.2 and 3 correcte

Evaluation of the effectiveness of age macular degeneration treatment

We examined 176 patients with an established diagnosis of age-related macular degeneration 'dry* form in the early and intermediate stages. The average age - 71,2 + 2,6, the average duration of the disease from the time of diagnosis of the disease 1,9 ± 1,3 years. All patients were divided into two groups: primary - 90 people and a comparison group of 86 people. The study group consisted of patients who underwent neyroprotektional vasodilator therapy: 5 mg Retinalamin subconjunctival injection number 10 and intramuscular injections of nicotinic acid 2,0 № 10. In the comparison group performed neuroprotective and vasodilator therapy in combination simpatocorrection number 10. The result has been found most effective therapeutic strategy: simpatocorrection in combination with the following regimen: 5 mg subconjunctival injection Retinalamin number 10, and intramuscular injection of nicotinic acid, 2.0 N° 10.Нами обследовано 176 больных с установленным диагнозом возрастной макулярной дегенерации «сухая» форма в ранней и промежуточной стадиях. Средний возраст-71,2 + 2,6, средняя продолжительность заболевания от момента диагностики заболевания 1,9+1,3 года. Все пациенты были разделены на две группы: основную - 90 человек и группу сравнения 86 человек. В основную группу вошли пациенты, которым была проведена нейропротекторнаяи сосудорасширяющая терапия: Ретиналамин 5 мг субконъюнктивально №10 и внутримышечные инъекции никотиновой кислоты 2,0 №10. В группе сравнения проводилась нейропротекторная и сосудорасширяющая терапия в сочетании симпатокоррекцией №10. В результате была выявлена наиболее эффективная терапевтическая стратегия, а именно, сочетание симпатокоррекции со следующей схемой лечения: Ретиналамин 5 мг субконъюнктивально № 10, внутримышечные инъекции никотиновой кислоты 2.0 №10

The Use of Nutraceuticals in Patients with “Dry” Form of Age-Related Macular Degeneration on the Background of Accelerated Aging

The lutein-containing vitamin-mineral complex Retinorm, developed on the basis of the formula AREDS 2, with an optimal content of vitamins and minerals involved in antioxidant protection, is a potentially promising ophthalmic geroprotector.Purpose: to evaluate the effectiveness of vitamin-mineral complex “Retinorm” in patients with the dry form of AMD and accelerated pace of aging.Patients and Methods. The study involved 40 patients with a dry form of AMD (stage 2.3 according to AREDS classification) with an accelerated rate of aging (biological age of patients was measured by the method of Tokar, 1990). Gender distribution: men — 15 (37.5 %), women — 25 (62.5 %). The mean age of patients was 67.3 ± 6.8 years. Patients were divided into 2 groups. Patients of the study group (n = 20) were assigned “Retinorm” 1 capsule 3 times a day for 16 weeks. Patients of the control group (n = 20) were treated with “Lutein Forte” 1 capsule 2 times a day for 16 weeks. Visometry, perimetry, optical coherence tomography of the macular zone, measurement of biological age at the beginning of the study, at 2 and 4 months of the study, the tolerability of treatment in patients with a dry form of age — related macular degeneration on the background of taking dietary supplements-vitamin and mineral complexes with lutein and zeaxanthin.Results and discussion. As a result of treatment, there were the positive dynamics in terms of visometry and perimetry in the main and control groups. There were no negative dynamics of the indicators of thickness of the retina (in the area of the fovea), and increased macular volume in the main group. In the control group there was a weak tendency to the growth of these indicators. We found a significant positive effect of Retinol on the biological age of patients to 4 months of therapy. It allows to consider the drug as a promising ophthalmoscopy an agent. The results of the study showed the effectiveness of the inclusion of “Retinorm” in patients with the dry form of AMD. The proven geroprotective effect of “Retinorm” with good tolerability of treatment and the absence of side effects from all organ systems with a long term of administration allows us to recommend it for wide use in patients with a dry form of age-related macular degeneration, including patients with an accelerated rate of aging

Involutional entropion of the inferior eyelid and the ways of its correction

Целью данной работы является анализ нашего опыта хирургического лечения сенильных энтропионов нижнего века