10 research outputs found
Production and transformation of tobacco and Brassica containing macrochloroplasts
- Author
- Publication venue
- RMIT University
- Publication date
- 01/01/2009
- Field of study
Plastid division, sustained by the equilibrium expression and coordination of plastid division genes is vital for the maintenance of plastid populations in dividing plant cells. Macrochloroplasts (MCP), the occurrence of one or a few chloroplasts per cell is due to the imbalance in the expression of plastid division genes. Because of the MCP size and number it was proposed that they may provide better targets for the plastid transformation than the normal (WT) chloroplasts and result in better plastid transformation frequencies. The objective of this research was to produce transgenic plants containing macrochloroplasts by nuclear transformation and then to use these plants as a model for the development of plastid transformation of crop species. By using AtFtsZ1-1 and AtMinD1 as query sequences in the TIGR (U.S.A) and ASTRA (Australia) Brassica oleracea EST databases, this project resulted in the isolation of cauliflower FtsZ1-1 (EU684588) and MinD (EU684589) genes. In addition, AtFtsZ1-1 was used as a control gene for comparison to the cauliflower FtsZ1-1. Binary vectors were constructed to express these genes in tobacco and cauliflower either by Agrobacterium tumefaciens-mediated or PEG-mediated transformation methods. Transgenic tobacco and cauliflower plants with abnormal chloroplasts (MCP, minichloroplasts, honeycomb or doughnut shaped chloroplasts, uneven surface membrane chloroplasts) were developed. Furthermore, the transgenic tobacco and cauliflower plants were examined by PCR, RT-PCR and Southern blotting. In addition, th ese plants were also analysed for the different abnormal chloroplast phenotypes by fluorescence microscopy. This project also generated the first plastid transformants from macrochloroplast bearing tobacco plants via biolistics. After one round of regeneration homoplasmic plastid transformants were obtained from both WT chloroplast and MCP tobacco plants. The homoplasmic nature of plastid transformants were confirmed by PCR and Southern blotting. Plastid expression of GFP in WT and MCP was confirmed by fluorescence/confocal microscopy and western blot analysis. This project showed for the first time the characterisation of cauliflower FtsZ1-1 and MinD plastid division genes in homologous and heterologous systems (cauliflower and tobacco). Moreover, obtaining homoplasmic plastid transformant shoots from one round of regeneration from the MCP containing tobacco plants is reported for the first time in this study. In addition this study explored the effect of transgene expression level on the chloroplast abnormality, highlighting the importance of analysing transgenic tobacco and cauliflower plants at the protein lev el specifically with regard to plastid division genes. The maintenance of MCP phenotype in the regenerated shoots and the requirement of standardisation of MCP containing plants via biolistics for increasing the plastid transformation frequency were also examined
Production and characterisation of transgenic cauliflower plants containing abnormal chloroplasts
- Publication venue
- Elsevier BV (Netherlands)
- Publication date
- 01/01/2013
- Field of study
Macrochloroplasts, which can be produced by the imbalance expression of plastid division genes, may act as an alternative target tissue for the transformation of foreign genes especially by particle bombardment. This paper reports the production of stable transgenic cauliflower plants expressing cauliflower plastid division gene, BoMinD by using PEG mediated transformation of mesophyll protoplasts. Stable transgenic BoMinD cauliflower plants had abnormally shaped chloroplasts but these did not exhibit a true macrochloroplast or minichloroplast phenotype. Transgene number did not relate to the expression of the BoMinD transgene. Detection of total BoMinD by western blot suggests that the slight increase in total BoMinD levels resulted in honey-comb or doughnut shaped chloroplasts and irregular surface membrane chloroplasts
Regeneration from leaf explants and protoplasts of Brassica oleracea var. botrytis (cauliflower)
- Publication venue
- Elsevier B.V. (Amsterdam, The Netherlands)
- Publication date
- 01/01/2009
- Field of study
Adventitious shoot regeneration and protoplast isolation and culture were examined from leaf explants of in vitro shoot cultures of several cauliflower (Brassica oleracea var. botrytis) cultivars, sourced from Europe and Australia, was investigated with the aim to develop improved nuclear and plastid transformation protocols for this vegetable crop. Eight out of 10 cultivars regenerated shoots from at least 79% of leaf explants. Mesophyll protoplasts from leaves gave high yields and division frequencies. Growth of shoot cultures in large glass vessels with vented lids was the key factor in obtaining high protoplast division frequencies of up to 71% and at least 70% of protoplast calluses regenerating shoots
Socio-economic Impact of Tobacco Cultivation on Dalit Agricultural Laborers
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Biomarkers for the management of pre-eclampsia in pregnant women
- Publication venue
- Wolters Kluwer Medknow Publications
- Publication date
- 01/01/2013
- Field of study
Pre-eclampsia (PE) is a pregnancy related disorder characterized by hypertension and proteinuria noticeable after 20 wk of gestation. It is a leading cause of maternal and foetal mortality and morbidity worldwide. The aetiology of the disease is unknown, but recent studies have revealed that this disorder appears to originate in placenta and is characterized by widespread maternal endothelial dysfunction. Till date, delivery of placenta is the only cure for the disease. So, there is a need for the identification of highly specific and sensitive biochemical markers that would allow early identification of patients at risk and thus help in providing proper prenatal care. Several promising biomarkers have been proposed, alone or in combination, that may help in predicting women who are likely to develop PE. Maternal serum concentrations of these biomarkers either increase or decrease in PE during gestation. This review focuses on the various biomarkers available and their utility in predicting pre-eclampsia
Expression of Brassica oleracea FtsZ1-1 and MinD alters chloroplast division in Nicotiana tabacum generating macro- and mini-chloroplasts
- Publication venue
- Springer (Germany)
- Publication date
- 01/01/2012
- Field of study
FtsZ1-1 and MinD plastid division-related genes were identified and cloned from Brassica oleracea var. botrytis. Transgenic tobacco plants expressing BoFtsZ1-1 or BoMinD exhibited cells with either fewer but abnormally large chloroplasts or more but smaller chloroplasts relative to wild-type tobacco plants. An abnormal chloroplast phenotype in guard cells was found in BoMinD transgenic tobacco plants but not in BoFtsZ1-1 transgenic tobacco plants. Transgenic tobacco plants bearing the macro-chloroplast phenotype had 10 to 20-fold increased levels of total FtsZ1-1 or MinD, whilst the transgenic tobacco plants bearing the mini-chloroplast phenotype had lower increased FtsZ1-1 or absence of detectable MinD. We also described for the first time, plastid transformation of macro-chloroplast bearing tobacco shoots with a gene cassette allowing for expression of green fluorescent protein (GFP). Homoplasmic plastid transformants from normal chloroplast and macro-chloroplast tobacco plants expressing GFP were obtained. Both types of transformants accumulated GFP at similar to 6% of total soluble protein, thus indicating that cells containing macro-chloroplasts can regenerate shoots in tissue culture and can stably integrate and express a foreign gene to similar levels as plant cells containing a normal chloroplast size and number
Somatic Embryogenesis and Plant Regeneration from Hypocotyl and Leaf Explants of Brassica Oleracea var. Botrytis (Cauliflower)
- Author
- A. Ahmed
- A. Ali
- A. Kumar
- A. Vikrant
- B. Ahloowalia
- B. Vatsya
- D. Duncan
- E. William
- G. Schumann
- H. Murthy
- K. Eimert
- K. Martin
- L. Lv
- L. Pareek
- L. Watts
- M. Ikeda-Iwai
- M. Kieffer
- M. Kieffer
- N. Pogrebnyak
- O. Karami
- P. Bhalla
- P. Fransz
- P. Jourdan
- P. Namasivayam
- Q. Yang
- S. Zobayed
- T. Murashige
- V. Arnold
- V. Chikkala
- W. Sharp
- X. Leroy
- Y. Qin
- Publication venue
- 'Walter de Gruyter GmbH'
- Publication date
- Field of study
High efficiency transformation of Brassica oleracea var. botrytis plants by Rhizobium rhizogenes
- Author
- A Gerszberg
- A Kumar Ray
- Ch David
- D Vinterhalter
- DCW Brown
- EMR Metwali
- F Kong
- GD Nugent
- IJ Puddephat
- J Sambrook
- JJ Doyle
- K Hnatuszko-Konka
- K Hnatuszko-Konka
- LR Wilken
- LV Lingling
- M Ikeuchi
- M Kieffer
- MK Munshi
- MX Henzi
- NA Smith
- P Kumar
- P Theriappan
- PK Siong
- PL Bhalla
- PL Bhalla
- R Barański
- R Chakrabarty
- RA Jefferson
- S Pavlović
- SA Ravanfar
- SB Shahid
- T Murashige
- T Sretenović-Rajićić
- UK Laemmli
- V Baskar
- VMBG Spini
- VRN Chikkala
- VV Radchuk
- WJ Hurkman
- XJ Leroy
- XX Liu
- Y Yu
- Z Qamar
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- Author
- ?tinas A
- Aalem HAA
- Ababneh H
- Abbas A
- Abbas A
- Abbas H
- Abbasi A
- Abbassi F
- Abbasy J
- Abbood AH
- Abboud K
- Abdallah A
- Abdalsalam SJA
- Abdelaal A
- Abdelalemm M
- Abdelhafez MHZ
- Abdelhalim K
- Abdeljalil M
- Abdelkarem M
- Abdelmageed A
- Abdelmageed A
- Abdelmaksoud M
- Abdelmawgoud S
- Abdelmawla M
- Abdelmawla MOMK
- Abdelmoneim N
- Abdelnoor A
- Abdelrahman F
- Abdelrazek HA
- Abdelrhman R
- Abdelzaher A
- Abdelzaher AT
- Abdou K
- Abdoun M
- Abdualqader M
- Abdualqader MYM
- Abdulhaq A
- Abduljawad H
- Abdullaev A
- Abdullah NAN
- Abdulmonem A
- Abdulwahed E
- Abebrese J
- Abiyere H
- Abobakr AM
- Aboelfath S
- Abosamak NE
- Abu Harb Z
- Abu Hilal M
- Abu Hilal M
- Abu Jayyab M
- Abu-Elfatth AM
- Abu-Ghazal S
- Abu-Ghazal SY
- Abuali ASAME
- Abuelazm M
- Abuelnaga Y
- Abuelnaga Y
- Abughazal SY
- Abuleil A
- Abusannuga M
- Abuzaina K
- Adam I
- Aday U
- Adeyeye A
- Adeyeye NA
- Adham M
- Adhikari KM
- Affary AA
- Afzal A
- Afzal I
- Aghdassi A
- Ahmadi BE
- Ahmed EA
- Ahmed MBE
- Ahmed R
- Ahmeed
- Ajayi P
- Akahoshi K
- Akbar A
- Akhtar N
- Al-Abdi R
- Al-Abed O
- Al-Ameri S
- Al-Ameri SAAS
- Al-Asadi MAMM
- Al-Dowsh NA
- Al-Eryani F
- Al-Faiq S
- Al-Haj A
- Al-Hyari A
- Al-Isawi A
- Al-juaifari MA
- Al-Khawlani Q
- Al-Kubati W
- Al-Maadani B
- Al-Mallah R
- Al-Markiz E
- Al-Mekhlafi A
- Al-Melhani W
- Al-Naggar H
- Al-Naggar H
- Al-Ogaili M
- Al-Qasrawi S
- Al-Saban R
- Al-saban RAM
- Al-Sader MA-J
- Al-Samawi A
- Al-Samawi H
- Al-Sarireh B
- Al-Shami K
- Al-shami M
- Al-sharabi EAE
- Al-Shehari M
- Al-Tekreeti S
- Alahmed F
- Alahmed H
- Alaimo L
- Alali MB
- Alannaz O
- Alansary MN
- Alatise O
- Alattas Z
- Alawna R
- Alazab E
- Albaba S
- Albakry R
- Albar A
- Albaraesi MN
- Albarouni S
- Albishti A
- Alboridy M
- Aldoescu S
- AlDowsh NA
- Aldressi W
- Aldumaini H
- Alegria CR
- Alfano MS
- Alfatah MA
- Alfonso C
- Alfurais S
- Alghazo H
- Alhaboob N
- Alharthi M
- Alhashemi M
- Alhmaidi R
- Alhouri A
- Alhouri AN
- Ali AYM
- Ali D
- Ali RAAY
- Ali RAY
- Ali SB
- Alissawi S
- Alissawi SZ
- Aliwy MA
- Aljaber A
- Aljamal S
- Aljiffry M
- Alkhadem MA
- Alkhaleel W
- Alkhateb H
- Allah MA
- Allam A
- Allam M
- Allam S
- Allisiardi F
- Alloush A
- Almarashi H
- Almarkiz E
- Almasri TA
- Almassaudi A
- Almekhlafi T
- Almiani S
- Almjersah A
- Alnammourah WM
- Alnammourah WM
- Alnimr A
- Aloulou M
- Alowjali F
- Alsabah M
- Alsabbagh F
- AlSaffaf M
- Alsanany GM
- Alsayadi R
- Alshaghel M
- Alsharabi E
- Alshareea E
- Alsharif D
- Alsharif DS
- Alsharif DS
- Alsharif DS
- Alshatshat A
- Alsori M
- Alsoudani A
- Altatari A
- Altatari AM
- Alwafy K
- Alwan HM
- Alyasin I
- Alzabadiah AHM
- Alzghoul MW
- Alzoubi M
- Amarin Z
- Amic F
- Amina H
- Ammar K
- Amrani L
- Amrani ME
- Amro S
- Amro S
- Anas O
- Anas O
- Anastasi A
- Anatolievna LN
- Andersson B
- Andersson R
- Andrade JCB
- Andreou A
- Andreuccetti J
- Andriola V
- Andujar RL
- Ang D
- Angelico R
- Anghinoni M
- Aniukstyte L
- Anthoni C
- Antic A
- Antonucci A
- Anyla M
- Apel R
- Apers T
- Apostolos K
- Apostolou C
- Apostolou C
- Appeltans B
- Appeltans B
- Appukuttan M
- Arabiyat H
- Arabiyat HAA
- Arbutina D
- Arbutina D
- Ardhanari R
- Ardito F
- Argüello P
- Arıkan T
- Arıkan TB
- Arkadopoulos N
- Armentano S
- Arnau ABM
- Aroori S
- Artigues E
- Asano T
- Asghar M
- Atanasov B
- Atici AE
- Atici SD
- Atstupens K
- Attalla A
- Augustinus S
- Ausania F
- Avgerinos K
- Awad AK
- Awad S
- Awad S
- Awadi S
- Awan AA
- Aya B
- Aydin H
- Aydoğan S
- Ayoub S
- Azab MA
- Azaman NSBB
- Azizeh O
- Azizian A
- Azman A
- Azri YA
- Azzam A
- Babor R
- Babu E
- Bacalbaşa N
- Badovinac D
- Badr H
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- Badran Y
- Bagmet N
- Bahaa M
- Bahroun S
- Bahroun SG
- Bahroun SG
- Baiocchi GL
- Bairamidis E
- Bajjah H
- Bajjah HM
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- Balalis D
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- Balduzzi A
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- Balzan S
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- Banting S
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- Barakat A
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- Baraket O
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- Baranov AI
- Barauskas G
- Barberis A
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- Barbu ST
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- Barros AV
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- Batova A
- Bayhan H
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- Bayomi A
- Bedzhanyan A
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- Belyaev A
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- Benamwor A
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- Benkabbou A
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- Bentabak K
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- Berrevoet F
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- Besselink M
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- Beugniez C
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- Bilyak A
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- Binnawara M
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- Bleem HA
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- Borghi F
- Bork U
- Boterbergh K
- Bouali I
- Bouaoud S
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- Boudjenan-Serradj N
- boumzebra Y
- Boumzebra Y
- Bounaim A
- Bourazani M
- Boutti AS
- Bouzid C
- Bowne W
- Bozhkov VM
- Boñar NL
- Bracke B
- Braicu V
- Bramis K
- Bratlie SO
- Brañes A
- Brañes A
- Brebu D
- Bredikhin M
- Brennfleck FW
- Brezean I
- Brizzolari M
- Brizzolari M
- Brolese A
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- Brum SL
- Brunner M
- Brunner S
- Brustia R
- Buarque IL
- Bubalo T
- Buckel E
- Bulian D
- Bull N
- Burda L
- Burgan D
- Burnett D
- Burridge I
- Bursics A
- Buscemi S
- Busch O
- Busquets J
- Busset MDD
- Butori E
- Butt U
- Butt UI
- Butte J
- Butturini G
- Buwaitel MM
- Byshetty R
- Caccamo L
- Cai L
- Calabrese F
- Calabretto F
- Calik B
- Callery M
- Campagnaro T
- Caneparo A
- Canonico G
- Canteras CA
- Cantos M
- Capitanich P
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- Capurso G
- Caputo D
- Carganico G
- Carino NDL
- Carr-Boyd P
- Carvalho N
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- Casupang A
- Catrina E
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- Cerdeño R
- Cereda M
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- Chaturvedi A
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- Chatzis I
- Chatzizacharias N
- Chaudhry AA
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- Chernopolsky PM
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- Cheverdiuk D
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- Chisthi MM
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- Ciola M
- Cirelli R
- Ciubotaru C
- Clancy T
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- Coayla G
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- Coimbra F
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- Coppa J
- Coppola A
- Cossa A
- Cotsoglou C
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- Crinò SF
- Cristaudi A
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- Cross A
- Cruz MC
- Cuadrado A
- Cucchetti A
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- Cuticone G
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- de Meijer V
- De Mello E
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- Degisors S
- Deiana G
- del Carmen Manzanares Campillo M
- Del Chiaro M
- Del Mar Rico-Morales M
- Delis S
- Demetrashvili Z
- Demetrashvili Z
- Dervenis C
- Devar JW
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- Dimofte GM
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- Dominguez-Rosado I
- Domínguez RS
- Donati M
- Dondossola D
- Dorcaratto D
- Dorovinis P
- dos Santos IB
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- Drozdov E
- Duaigües MLG
- Duberman B
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- Dulskas A
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- Faraj WG
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- Farhat H
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- Farouk A
- Fathallah D
- Fathallah D
- Fayed A
- Fedele S
- Felekouras E
- Felekouras GE
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- Feo C
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- Teh C
- Teixeira UF
- Tekin E
- Tenreiro N
- Tepetes K
- Tesarikova J
- Testa V
- Testini M
- Tez M
- Thakkar R
- The C
- Theab M
- Theab RAK
- Thiruchelvam N
- Thomaidis P
- Thompson R
- Tidjane A
- Tijani EH
- Tilak S
- Tingstedt B
- Tinguely P
- Tinguely P
- Tishreen AH
- Tisone G
- Titi R
- Tobba TM
- Tokarev M
- Tolin F
- Tolis EAN
- Tomara N
- Tomara NK
- Tomazic A
- Tommaso S
- TomአS
- Tonini V
- Tooulias A
- Torab SS
- Torelly L
- Torgomyan G
- Torres O
- Torres OJM
- Torres SM
- Torres-Quevedo R
- Toso C
- Touabti S
- Toutouzas K
- Triantafyllidis I
- Tripathi M
- Trizzino A
- Troci A
- Troisi RI
- Trotovšek B
- TrotovŠek B
- Truant S
- Tsakiris C
- Tsalis K
- Tsaramanidis S
- Tschuor C
- Tsiotos G
- Tsirlis T
- Tsoukalas N
- Tumas J
- Tuvin D
- Tyutyunnik P
- Tzimas G
- Tölgyes T
- Türkoğlu MA
- Tüzüner A
- Uemura K
- Uggeri F
- Ugrekhelidze K
- Uguz A
- Uhl W
- Ulgur HS
- Ullah S
- Unalp OV
- Urciuoli I
- Uzir SSBM
- Uzunoglu FG
- Vaia A
- Vailas M
- Vaishnav D
- Val AR-D
- Valaroutsos A
- Valcarcel AQ
- Valente R
- Valeriia S
- Valladares AM
- Valmorisco MA
- Valverde DP
- Van Dam JL
- Van den Bossche B
- van Eijck CH
- van Laarhoven S
- Vanagas T
- Varshney V
- Vasavada B
- Vaslamatzis M
- Vass D
- Vassiliu P
- Vazquez PG
- Velagala JR
- Velagala JR
- Velenciuc N
- Velázquez PS
- Veneroni L
- Venkatesh NR
- Vennarecci G
- Vera V
- Vereczkei A
- Vezakis A
- Vigia E
- Vilcu M
- Vilhav C
- Vincenti L
- Virk S
- Vishnoi JR
- Viswanathan K
- Vito D
- Vivarelli M
- Vladov N
- Vodyala C
- Vougas V
- Vouros D
- Vrakopoulou GZ
- Waechter FL
- Waffa Z
- Wagner K
- Wahib EM
- Wake R
- Wang H
- Wang J
- Waqar U
- Waqar U
- Wardeh S
- Wardeszkiewicz A
- Wassmer C-H
- Weber M
- Wei A
- Wei K
- Wei K
- Weitz J
- Wellner U
- Welsch T
- Welsh F
- Wen D
- Wennerblom JH
- Wenning AS
- Wicherts D
- Wierzchowski M
- Wikar T
- Williamsson C
- Windsor J
- Winslow E
- Wlazlak M
- Wolfgang C
- Wu CH
- Wu CH
- Wyroślak-Najs J
- Wüllenweber H-P
- Yadav K
- Yadev I
- Yadev I
- Yaghan R
- Yamamoto T
- Yang P-C
- Yassin LMA
- Yassin R
- Yegen C
- Yeo C
- Yesilyurt D
- Yip V
- Yoong B
- Yoong BK
- Younes E
- Younes E
- Young A
- Yousef A
- Youssef A
- Yu M-C
- Zacharakis E
- Zacharoulis D
- Zachiotis M
- Zagainov V
- Zaharie F
- Zahed M
- Zahed MSM
- Zakaria AD
- Zamri FMB
- Zanatta M
- Zanello M
- Zanini N
- Zanus G
- Zanus G
- Zaruba P
- Zawia A
- Zayed A
- Zdujic P
- Zedelj J
- Zeh HJ
- Zentar A
- Zerbi A
- Zidan T
- Zidan T
- Zironda A
- Zitawi A
- Zivanovic M
- Zogopoulos G
- Zonta S
- Zonta S
- Zorrilla CF
- Zozaya G
- Zreqat Q
- Zuhdi Z
- Zuhdy M
- Zygomalas A
- álvarez PM
- çelik M
- çetiindağ Ö
- Çiftci AB
- çoker A
- öfkeli Ö
- özet A
- Šileikis A
- Šlepavičius A
- Štironja I
- Publication venue
- Publication date
- 18/01/2024
- Field of study
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
- Author
- A Nizarudeen
- Aalem Hajer Abd Alhamed
- Ababneh Hazim
- Abbas Ahmed
- Abbas Aram
- Abbas Hussain
- Abbasi Arezou
- Abbassi Fariba
- Abbasy Jibran
- Abbood Ali H
- Abboud Kirellos
- Abdallah Ahmed
- Abdalsalam Sabriya Juma Ali
- Abdelaal Abdelrahman
- Abdelalemm Mohamed
- Abdelhafez Mohammed Hisham Zayan
- Abdelhalim Karim
- Abdeljalil Mahmoud
- Abdelkarem Mohamed
- Abdelmageed Abdelfatah
- Abdelmageed Abdelfatah
- Abdelmaksoud Mohamed
- Abdelmawgoud Sherif
- Abdelmawla Mohamed
- Abdelmawla Mohamed Osama Mohammed Kamel
- Abdelmoneim Noha
- Abdelnoor Ahmad
- Abdelrahman Fatma
- Abdelrazek Hussein A
- Abdelrhman Reham
- Abdelzaher Abdurrahman
- Abdelzaher Abdurrahman Taha
- Abdou Khaled
- Abdoun Meriem
- Abdualqader Mahmmoud
- Abdualqader Mahmmoud Yehia Mohammed
- Abdulhaq Aram
- Abduljawad Heba
- Abdullaev Abakar
- Abdullah Nik Azim Nik
- Abdulmonem Aya
- Abdulwahed Eman
- Abebrese John
- Abiyere Henry
- Abobakr Abobakr Mahfoz
- Aboelfath Shiamaa
- Abosamak Nour Eldin
- Abu-Elfatth Ahmed Mohammed
- Abu-Ghazal Sara
- Abu-Ghazal Sara Yassir
- Abuali Ahmed S A M E
- Abuelazm Mohamed
- Abuelnaga Yasmeen
- Abuelnaga Yasmeen
- Abughazal Sara Yasser
- Abuleil Amro
- Abusannuga Malek
- Abuzaina Khalil
- Adam Islam
- Aday Ulaş
- Adeyeye Ademola
- Adeyeye Nigeria Ademola
- Adham Mustapha
- Adhikari Krishna Mohan
- Affary Anter Al
- Afzal Ameer
- Afzal Iqraa
- Aghdassi Ali
- Ahmed Emad Ali
- Ahmed Mohamed Bahaa Eldin
- Ahmed Randa
- Ahmeed Sultan
- Ajayi Peter
- Akahoshi Keiichi
- Akbar Ali
- Akhtar Naseem
- Al-Abdi Radfan
- Al-Abed Omar
- Al-Ameri Saba
- Al-Ameri Saba Ahmed Ahmed Saleh
- Al-Asadi Mohammed Abdulkhaleq Mohammed Mohsen
- Al-Dowsh Nagra Are
- Al-Eryani Fatima
- Al-Faiq Siham
- Al-Haj Ahmad
- Al-Hyari Abdelkareem
- Al-Isawi Ali
- Al-juaifari Maytham Aqeel
- Al-Khawlani Qaeid
- Al-Kubati Waheeb
- Al-Maadani Basma
- Al-Mallah Rozana
- Al-Markiz Eman
- Al-Mekhlafi Ayat
- Al-Melhani Watheeq
- Al-Naggar Hamza
- Al-Naggar Hamza
- Al-Ogaili Mustafa
- Al-Qasrawi Shahd
- Al-Saban Rafat
- Al-saban Rafat Ameen Mohammed
- Al-Sader Maytham Al-Juaifari
- Al-Samawi Abdulaziz
- Al-Samawi Hytham
- Al-Sarireh Bilal
- Al-Shami Khayry
- Al-shami Manar
- Al-sharabi Ebrahim Ahmed Esmail
- Al-Shehari Mohammed
- Al-Tekreeti Sarah
- Alahmed Farouq
- Alahmed Hoor
- Alaimo Laura
- Alali Mahmoud Bilal
- Alannaz Omar
- Alansary Marwa Nasrelden
- Alatise Olusegun
- Alattas Zainab
- Alawna Reem
- Alazab Emad
- Albaba Safa'
- Albakry Rudaina
- Albar Aisha
- Albaraesi Mohammed N
- Albarouni Sofian
- Albishti Ahmed
- Alboridy Muneera
- Aldoescu Sorin
- AlDowsh Nagran Aref
- Aldressi Wafa
- Aldumaini Hamdan
- Alegria Cesar Rodriguez
- Alfano Marie Sophie
- Alfatah Maryam Abd
- Alfonso Cenon
- Alfurais Sarah
- Alghazo Heyam
- Alhaboob Nassir
- Alharthi Mohammed
- Alhashemi Mais
- Alhmaidi Riad
- Alhouri Ahmad
- Alhouri Ahmad Nabil
- Ali Ahmed Youssef Mohamed
- Ali Dina
- Ali Ramzi Abdullah Yahya
- Ali Ramzi Ali Abdullah Yahya
- Ali Suhil Ben
- Alissawi Subhi
- Alissawi Subhi Zahi
- Aliwy Marwan Al
- Aljaber Ahmad
- Aljamal Sarah
- Aljiffry Murad
- Alkhadem Maeen Ali
- Alkhaleel Wael
- Alkhateb Hossain
- Allah Mohamed Abd
- Allam Ahmed
- Allam Mohamed
- Allam Shrouq
- Allisiardi Fabrizio
- Alloush Ali
- Almarashi Hassan
- Almarkiz Eman
- Almasri Tabarak Abedlnaser
- Almassaudi Ali
- Almekhlafi Tofik
- Almiani Sari
- Almjersah Abdulrahman
- Alnammourah Walaa Mohammed
- Alnammourah Walaa Mohammed
- Alnimr Ahmed
- Aloulou Marwa
- Alowjali Fatoom
- Alsabah Mohamed
- Alsabbagh Feras
- AlSaffaf Mohamed
- Alsanany Ghadeer Mohammed
- Alsayadi Ramzi
- Alshaghel Mohammed
- Alsharabi Ebrahim
- Alshareea Entisar
- Alsharif Doaa
- Alsharif Doaa Sabry
- Alsharif Doaa Sabry
- Alsharif Doaa Sabry
- Alshatshat Abdulhadi
- Alsori Mohamed
- Alsoudani Ali
- Altatari Abdulrahman
- Altatari Ahmad Mohammad
- Alwafy Khaled
- Alwan Hussein Mohammed
- Alyasin Ismaeil
- Alzabadiah Asmaa Hasan Mohammad
- Alzghoul Mohammad W
- Alzoubi Mohammed
- Amarin Zouhair
- Amic Fedor
- Amina Houmada
- Ammar Khaled
- Amrani Laila
- Amro Sarah
- Amro Sarah
- Anas Omar
- Anas Omar
- Anastasi Alessandro
- Anatolievna Li Natalya
- Andersson Bodil
- Andersson Roland
- Andrade Juan Camilo Barreto
- Andreou Andreas
- Andreuccetti Jacopo
- Andriola Valeria
- Andujar Rafael López
- Ang Dr Dante
- Angelico Roberta
- Anghinoni Marciano
- Aniukstyte Laura
- Anthoni Christoph
- Antic Andrija
- Antonucci Adelmo
- Anyla Morgan
- Apel Roy
- Apers Thomas
- Apostolos Kambaroudis
- Apostolou Christos
- Apostolou Christos
- Appeltans Bart
- Appeltans Bart
- Appukuttan Murali
- Arabiyat Hamza
- Arabiyat Hamza Ayman Abdelhalem
- Arbutina Dragana
- Arbutina Dragana
- Ardhanari Ramesh
- Ardito Francesco
- Argüello Pedro
- Arıkan Turkmen
- Arıkan Türkmen Bahadır
- Arkadopoulos Nikolaos
- Armentano Serena
- Arnau Ana Belen Martin
- Aroori Somaiah
- Artigues Enrique
- Asano Toshimichi
- Asghar Mohammad
- Atanasov Boiko
- Atici Ali Emre
- Atici Semra Demirli
- Atstupens Kristaps
- Attalla Almoatazbellah
- Augustinus Simone
- Ausania Fabio
- Avgerinos Konstantinos
- Awad Ahmed K
- Awad Selmy
- Awad Selmy
- Awadi Sajeda
- Awan Altaf Awan
- Aya Boudouh
- Aydin Husnu
- Aydoğan Serdar
- Ayoub Seba
- Azab Mohammed A
- Azaman Nur Sabrina Binti Babe
- Azizeh Oula
- Azizian Azadeh
- Azman Azlanudin
- Azri Yahya Al
- Azzam Ahmed
- álvarez Pablo Muriel
- Babor Richard
- Babu E
- Bacalbaşa Nicolae
- Badovinac David
- Badr Helmy
- Badr Karim
- Badran Youssef
- Bagmet Nikolay
- Bahaa Mohamed
- Bahroun Sumayyah
- Bahroun Sumayyah Ghayth
- Bahroun Sumayyah Ghayth
- Baiocchi Gian Luca
- Bairamidis Eugenios
- Bajjah Hadeel
- Bajjah Hadeel Mohmmed
- Bajjah Hadeel Muhammed Ahmed Hussein
- Balalis Dimitrios
- Balci Deniz
- Baldi Caterina
- Balduzzi Alberto
- Ballarin Roberto
- Baltagiannis Evangelos
- Balzan Silvio
- Bansal Varun
- Banting Samuel
- Banting Simon
- Barakat Ahmed
- Barakat Ahmed Tarek Mohamed
- Baraket Oussama
- Baraket Oussama
- Baranov Andrey Igorevich
- Barauskas Giedrius
- Barberis Andrea
- Barbier Louise
- Barbu Sorin Traian
- Barbu Sorin Traian
- Bareig Elham
- Bari Hassaan
- Barros Aldo Vieira
- Barroso Ryan Ruel
- Bartella Isabel
- Bartlett Adam
- Bartos Adrian
- Bashir Manahil
- Basile Prof Francesco
- Bassi Claudio
- Bassi Domenico
- Bassiony Mahmoud
- Batova Anastasia
- Bayhan Hüseyin
- Bayhan Zulfu
- Bayomi Abdulrahman
- Bedzhanyan Arkady
- Belaid Wafae Ait
- Belal Mohamed
- Belev Nikolay
- Belev Nikolay
- Belkhadir Zakaria
- Belli Andrea
- Belloni Elena
- Beltran-Miranda Pablo
- Belyaev Alexander
- Belyaev Orlin
- Benamwor Aihab
- Bencini Lapo
- Benedetto Fabrizio Di
- Benkabbou Amine
- Benkabbou Amine
- Bentabak Kamel
- Bentabak Kamel
- Benuzzi Laura
- Beradze Nikolaos
- Berrevoet Frederik
- Berry Roger
- Besselink Marc
- Besselink Marc G
- Beugniez Cesar
- Bezmarevic Mihailo
- Bhalerao Suryabhan
- Bhandari Ramesh Singh
- Bhatti Imran
- Bhogal Ricky
- Bieze Matthanja
- Bilyak Andriy
- Bindra Vanshay
- Binnawara Muhannud
- Bjornsson Bergthor
- Bleem Hikma Abdullh
- Boalot Ahmed
- Bodea Raluca
- Boff Marcio
- Bogdanovic Aleksandar
- Bogdanovic Marko
- Boggi Ugo
- Bolli Martin
- Bong Jin
- Bonomo Michele
- Boñar Nuria Losa
- Boone Brian
- Borakati Aditya
- Borghi Felice
- Bork Ulrich
- Boterbergh Kim
- Bouali Imene
- Bouaoud Souad
- Bouaziz Hanen
- Boudjenan-Serradj Nabil
- boumzebra yassmine
- Boumzebra Yassmine
- Bounaim Ahmed
- Bourazani Maria
- Boutti Ahmed Sami
- Bouzid Chafik
- Bowne Wilbur
- Bozhkov Vasil Markov
- Bracke Bart
- Braicu Vlad
- Bramis Konstantinos
- Brañes Alejandro
- Brañes Alejandro
- Bratlie Svein Olav
- Brebu Dan
- Bredikhin Mikhail
- Brennfleck Frank W
- Brezean Iulian
- Brizzolari Marco
- Brizzolari Marco
- Brolese Alberto
- Brown Kai
- Brown Lisa
- Brum Sarah L
- Brunner Maximilian
- Brunner Stefan
- Brustia Raffaele
- Buarque Igor Lima
- Bubalo Tomislav
- Buckel Erwin
- Bulian Dirk
- Bull Nicholas
- Burda Lukas
- Burgan Dania
- Burnett David
- Burridge Isobel
- Bursics Attila
- Buscemi Salvatore
- Busch Olivier
- Busquets Juli
- Busset Michele Droz dit
- Butori Eugenia
- Butt Usman
- Butt Usman Ismat
- Butte Jean
- Butturini Giovanni
- Buwaitel Mohammad Musallam
- Byshetty Rajendar
- Caccamo Lucio
- Cai Lei
- Calabrese Francesco
- Calabretto Francesca
- Calik Bulent
- Callery Mark
- Campagnaro Tommaso
- Caneparo Andrea
- Canonico Giuseppe
- Canteras Carlos Augusto
- Cantos Dra Míriam
- Capitanich Pablo
- Capoglu Recayi
- Capurso Gabriele
- Caputo Damiano
- Carganico Giacomo
- Carlo Isidoro Di
- Carr-Boyd Peter
- Carvalho Nubyhelia
- Casadei Riccardo
- Castro Maria
- Castro Tiago
- Casupang Amornetta
- Catrina Eduard
- Celotti Andrea
- Cerdeño Ruby
- Cereda Marco
- Ceresa Carlo
- Chaaban Majd
- Chaaban Mohammad Karam
- Chaaban Mohammad Karam
- Chabot John
- Chakravartty Saurav
- Chand Jithin Thulsi
- Chang David
- Chardalias Leonidas
- Chardarov Nikita
- Chasiotis Dimitrios
- Chattopadhyay Somnath
- Chaturvedi Arun
- Chatzialis Iosif
- Chatzis Iosif
- Chatzizacharias Nikolaos
- Chaudhry Ahmad Areeb
- Chaudhury Prosanto
- Chen Stanley
- Chen Yiming
- Cherif Rim
- Chernopolsky Plamen Milchev
- Cheung Tan To
- Cheverdiuk Dmytro
- Chibane Aissam
- Chierici Andrea
- Chihaka Onesai
- Chihaka Onesai
- Chik Ian
- Chikkala Bhargava
- Chiow Adrian
- Chisthi Meer M
- Chong Lynn
- Chooklin Serge
- Choudhary Satyaprakash Ray
- Chowdhury Mohammad
- Christodoulidis Grigorios
- Christodoulou Spyridon
- Christophides Thalis
- Christophides Thalis
- Christou Chrysanthos
- Chu Michael Jen Jie
- Chuklin Serhii
- Ciarleglio Francesco
- Ciesielski Wojciech
- Cillo Umberto
- Ciola Michele
- Cirelli Riccardo
- Ciubotaru Cezar
- Clancy Thomas
- Clavien Pierre-Alain
- Coayla Guillermo
- Cobianchi Lorenzo
- Coelho Gustavo
- Coelho Gustavo
- Coimbra Felipe
- Coimbra Felipe José Fernández
- Colak Elif
- Colledan Michele
- Compañ Antonio
- Conci Simone
- Conlon Kevin
- Connor Saxon
- Coppa Jorgelina
- Coppola Alessandro
- Cossa Alessandra
- Cotsoglou Christian
- Crespi Michele
- Crinò Stefano Francesco
- Cristaudi Alessandra
- Cristaudi Alessandra
- Croagh Daniel
- Cross Andrea
- Cruz Miguel Charco
- Cuadrado Angel
- Cucchetti Alessandro
- Cuk Vladica
- Cunningham Steven
- Cuticone Giuseppe
- Cyrochristos Dimitrios
- çelik Muhammet
- çetiindağ özhan
- Çiftci Ahmet Burak
- çoker Ahmet
- D'Acapito Fabrizio
- D'Souza Daniel
- D'Ugo Stefano
- da Silva Diego Vaz
- Dabbous Hany
- Dahhan Hiba Talal
- Dailidenas Sarunas
- Dallavalle Raffaele
- Daraghmeh Motaz Ayman Mahmoud
- Dario Lorenzin
- Das Kshaunish
- Dasari Bobby VM
- Dassanayake B K
- David Avril
- Davide José
- Davidson Brian
- Davydkin Vasili
- Dawood Ahmad Jamal
- De Cian Franco
- De Francesco Maura
- de Graaf Nine
- de Heredia Juan Beltran
- de la Hoz Rogriguez ángela
- de la Rúa Jorge F Roldán
- de la Serna Sofia
- de León Alberto Miyar
- De Marchi Francesco
- de Meijer VE
- De Mello Eduardo
- De Rosa Raffaele
- de Rose Agostino Maria
- de Santibanes Martin
- de Santibañes Martin
- De Simoni Ottavia
- de' Liguori Carino Nicola
- Dean Yomna E
- Dede Kristóf
- Degisors Sebastien
- Deiana Giulia
- del Carmen Manzanares Campillo María
- Del Chiaro Marco
- Del Mar Rico-Morales Maria
- Delis Spiros
- Demetrashvili Zaza
- Demetrashvili Zaza
- Dervenis Christos
- Devar John WS
- Devaud Nicolas
- Dharmapala Arinda
- Di Domenico Stefano
- Di Franco Gregorio
- Di Martino Marcello
- Diab Sherein
- Diaconescu Bogdan
- Diamantis Alexandros
- Diaz Christian
- Diaz Cristian
- Dickerson Lindsay
- Didomenico Stefano
- Dikicier Enis
- Dikmen Kursat
- Dima Simona
- Dimitrokallis Nikolaos
- Dimitroulis Dimitrios
- Dimofte Gabriel Mihali
- Dinerman Aaron
- Distler Marius
- Dixon Elijah
- Djokić Mihajlo
- Dkhakhni Abdulbari
- Dohien Mohamed
- Dohien Mohamed
- Dominguez-Rosado Ismael
- Domínguez Ramón Soliva
- Donati Marcello
- Dondossola Daniele
- Dorcaratto Dimitri
- Dorovinis Panagiotis
- dos Santos Ian Barroso
- Douba Zain
- Döbereiner Jessica
- Drid Boutheyna
- Drozdov Evgeniy
- Duaigües Marta Lourdes Gonzalez
- Duberman Boris
- Dugalic Vladimir
- Dulskas Audrius
- Dulskas Audrius
- Dulundu Ender
- Dumitrascu Traian
- Dunne Declan
- Dupré Aurélien
- Dural Ahmet Cem
- Durczynski Adam
- Duta Ciprian
- Duzgun Ozgul
- Dziakova Jana
- Ealreibi Hajer
- Ebrahim Hussein
- Echiguer Sabrillah
- Efthymiou Evripidis
- Eid Mouhanad
- Eisa Reem
- Eismontas Vitalijus
- Ekhmaj Reyad
- Ekhmaj Reyad
- El Ahmadi Brahim
- El Amrani Mehdi
- El Behi Amor
- El Gady Ammar
- El Gady Ammar
- El Garhy Mahmoud
- El Gohary Mohamed
- El Hussain Ramadan Kamoka
- El Moneam Mohamed Abd
- El-Najjar Amro
- El-Sayes Islam
- Elabd Mohamed
- Elareibi Hajer Ehab
- Elazeem Hossam Aldein Abd
- Elbadawy Merihan A
- Elbalka Saleh S
- Elbassyiouny Ahmed
- Elboraei Rahma
- Eldabour Ahmed
- Eldaly Abdullah
- Eldaly Abdullah Sami
- Eleisawy Mahmoud
- Eleisawy Mahmoud Fares
- Elfarag Hagar Abo
- Elfiky Mahmoud
- Elgarhy Ibrahim
- Elgarhy Ibrahim Mohamed
- Elgharably Ahmed Abdelfattah
- Elhadi Muhammed
- Elhadi Muhammed
- Elhadi Muhammed
- Elhajdawe Fras
- Elhamamsy Mohamed
- Elhassan Manar
- Elhassouni Reda
- Elkeleny Mostafa
- Elkhuja Taha
- Ellafi Amera Ali Dakheel
- Ellibady Mohamed
- Elmalah Merna
- Elmeteini Mahmoud
- Elmorsi Rami
- Elmzaien Eman
- Elnabawy Dina
- Elnabi Mahmoud Hasab
- Elnagar Mohamed
- Elnashar Amr
- Elnoamany Salma
- Elsaadany Reem
- Elsakka Abdelrahman
- Elsayed Nada
- Elshafey Ahmed
- Elwakil Lama
- Elweza Omnia
- Emar Mohammad
- Emar Mohammad Farid Mohammad
- Emhemed Marwa
- Eminesariipek N
- Emral Ahmet Cihangir
- Enoch Elizabeth
- Enriquez Juan Carlos Marcos
- Entschev Alexandra
- Ercolani Giorgio
- Erdene Sarnai
- Erdene Sarnai
- Ertekin Suleyman
- Escartín Alfredo
- Esmail Muhib
- Essa Mostafa
- Fadel Bashir A
- Fahim Abdelrahman
- Fahim Abdelrahman Mohamed
- Fahmy Marina
- Fairweather Mark
- Fakhradiyev Ildar
- Fakhradiyev Ildar
- Falconi Massimo
- Falconi Massimo
- Falgueras Laia
- Farag Marina
- Farag Mostafa
- Faragalla Hazem
- Faraj Sireen
- Faraj Sireen Mahmoud
- Faraj Tasneem
- Faraj Walid Ghazi
- Fareed Ahmed M
- Farhat Heba
- Farid Ahmed
- Farid Mohammad
- Farkas Stefan A
- Farouk Ahmed
- Fathallah Dalia
- Fathallah Dalia
- Fayed Aly
- Fedele Salvatore
- Felekouras Evangelos
- Felekouras Greece Evangelos
- Felli Emanuele
- Feo Claudio
- Fergadi Maria
- Fernandes Carlos
- Fernández Jose Miguel Vargas
- Fernández Rocio
- Ferrara Francesco
- Ferrari Carlo
- Ferrari Giovanni
- Ferraro Daniele
- Ferraro Daniele
- Ferreira Fabio
- Ferrero Alessandro
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- kivisild margus
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- Konstantinidis Michael K
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- Martinsone Katrina Deja
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- Marumo Thomas
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- Meerdink M
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- Oldani Graziano
- Oldhafer Karl J
- Oliver Tiffany
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- Yadav Kaushal
- Yadev Induprabha
- Yadev Induprabha
- Yaghan Rami
- Yamamoto Tomohisa
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- Yassin Raya
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- Yoong Boon Koon
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- Younes Eman
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- Yousef Amal
- Youssef Amal
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- Zacharakis Emmanouil
- Zacharoulis Dimitrios
- Zachiotis Marinos
- Zagainov Vladimir
- Zaharie Florin
- Zahed Mohamed
- Zahed Mohamed Samir Mohamed
- Zakaria Andee Dzulkarnaen
- Zamri Fatimah Mardhiyyah Binti
- Zanatta Michela
- Zanello Matteo
- Zanini Nicola
- Zanus Giacomo
- Zanus Giacomo
- Zaruba Pavel
- Zawia Ali
- Zayed Ahmed
- Zdujic Predrag
- Zedelj Jurica
- Zeh Herbert J
- Zentar Aziz
- Zerbi Alessandro
- Zidan Taha
- Zidan Taha
- Zironda Andrea
- Zitawi Abdullah
- Zivanovic Marko
- Zogopoulos George
- Zonta Sandro
- Zonta Sandro
- Zorrilla Carlos Florez
- Zozaya Gabriel
- Zreqat Qusai
- Zuhdi Zamri
- Zuhdy Mohammad
- Zygomalas Apollon
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide.Methods: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters.Results: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 percent of patients (2901 of 4223). Major complication rates (Clavien-Dindo grade at least IIIa) were 24, 18, and 27 percent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 percent; however, it was 41 per cent in low-to-middle-compared with 19 per cent in very high-HDI countries.Conclusion: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761)