A GREEN NANO-BIOTECHNOLOGICAL APPROACH FOR THE SYNTHESIS OF SILVER NANOPARTICLES USING THE SEED COAT OF TAMARINDUS INDICA, STUDY OF ITS ANTIBACTERIAL AND ANTICANCER ACTIVITY

Objective: The present study was designed to investigate the antibacterial and anti cancer effect of silver nanoparticle synthesized using the seed coat extract of Tamarindus indica.Methods: In this study, aqueous extract of Tamarindus indica seed coat is used for synthesizing silver nanoparticles (AgNPs). Plant metabolites in the aqueous extract act as both reducing and capping agents resulting in the formation of stable and shape-controlled AgNPs. The AgNPs thus synthesized were characterized using UV-Vis absorption spectroscopy, FTIR and SEM analysis. The nanoparticles were tested for their antibacterial effect against human pathogenic bacteria and anticancer effect against HeLa cell line.Results: Our results suggested that the aromatic compounds like flavanoids in the plant extract are responsible for the reduction of AgNP's. SEM analysis revealed fairly well dimensioned square shaped nanocrystals. The results were positive proving that the synthesized AgNPs possess excellent antibacterial and anticancer properties. Conclusion: The synthesized AgNPs showed maximum anti-bacterial and anti-cancer effect.Â