Methyl 4-(3-eth­oxy-4-hydroxy­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate monohydrate

In the title compound, C15H18N2O5·H2O, the pyrimidine ring adopts a flattened-boat conformation. The eth­oxy group attached to the benzene ring is in an extended conformation. The oxopyrimidine mol­ecules are linked into centrosymmetric R 2 2(20) dimers by O—H⋯O hydrogen bonds. The dimers are linked by N—H⋯O hydrogen bonds, forming a two-dimensional network parallel to the bc plane. Adjacent networks are cross-linked via N—H⋯O and O—H⋯O hydrogen bonds involving the water mol­ecules

Diethyl 2-(2-nitro­benzyl­idene)malonate

In the title compound, C14H15NO6, the ethoxy­carbonyl groups adopt extended conformations. In the crystal, mol­ecules are linked into centrosymmetric dimers via pairs of C—H⋯O hydrogen bonds with a R 2 2(20) motif

N-(2-Formyl­phen­yl)benzene­sulfonamide

In the title compound, C13H11NO3S, the two aromatic rings are oriented at an angle of 88.18 (8)°. Intra­molecular N—H⋯O and C—H⋯O hydrogen bonds are observed, each of which generates an S(6) ring motif. In the crystal, mol­ecules are linked into C(7) chains along [010] by inter­molecular C—H⋯O hydrogen bonds. The structure is further stabilized by inter­molecular C—H⋯π inter­actions involving the sulfonyl-bound phenyl ring

Bio Characterization via FTIR and GCMS Analysis of Cucurbita variety (Yellow and White Pumpkin)

The current study aimed to conduct phytochemical screening, FTIR, and GCMS analysis in squash (Cucurbita pepo L.,) also known as a yellow and white selected pumpkin. It’s one of the dicotyledonous vegetables consumed in daily diets that imparts high inhibitor properties of inflammation, cancer, and diabetes. Traditionally it is used as an anti-helminthic remedy. The phytochemical characterization can facilitate seeking out the substance with a therapeutic property. The peel, flesh, and seed sample of each pumpkin variety were used as sources and extracted consecutively with ethyl acetate and acetonitrile using the maceration method. Phytochemical screening and quantification were carried out by standard analytical methods. The functional groups of the sample extracts were analyzed using FT-IR methods. Further, phytochemical profiling was carried out utilizing the GCMS technique to identify the therapeutically important chemicals contained in the sample. Phytochemical analysis of ethyl acetate and acetonitrile extracts showed the presence of major components like alkaloids, phenol, carbohydrate, and proteins. The farthest alkaloid, phenol, carbohydrate, and protein varied consequently for different parts like peel, flesh, and seed. The FT-IR analysis of each extract in the peel, flesh, and seed revealed that the ethyl acetate extract had the most functional groups. The major peak was characterized at wavelength 3004.24 to 3421.05 nm which indicates O-H functional group. Further quantification and GC-MS analysis were performed in ethyl acetate extract. Remarkably, GC-MS analysis of yellow and white pumpkin ethyl acetate extracts showed the utmost 6 - 8 compounds within the flesh part. Further, employing these compounds for anti-inflammatory and anti-microbial assays may aid in the discovery of new drugs for therapeutic applications

1,1′-[4-(4-Methoxy­phen­yl)-2,6-dimethyl-1,4-dihydro­pyridine-3,5-di­yl]diethanone

In the title compound, C18H21NO3, which belongs to the family of calcium channel blockers, the dihydropyridine ring assumes a flattened boat conformation. The two carbonyl units adopt a synperiplanar conformation with respect to the double bonds in the dihydro­pyridine ring. The methoxy­phenyl ring is almost perpendicular to the prydine ring [dihedral angle = 89.01 (7)°]. In the crystal, the mol­ecules are connected by inter­molecular N—H⋯O hydrogen bonds

tert-Butyl 3-[2,2-bis­(ethoxy­carbon­yl)vin­yl]-2-bromo­methyl-1H-indole-1-carboxyl­ate

In the title compound, C22H26BrNO6, the indole ring system is planar [maximum deviation 0.029 (2) Å]. The tert-butyl bound carboxyl­ate group forms a dihedral angle of 17.54 (8)° with the indole ring system. In the crystal, mol­ecules are linked into centrosymmetric R 2 2(10) dimers by paired C—H⋯O hydrogen bonds

1-(Phenyl­sulfon­yl)benzo[1,2:2′,3′]thieno[5′,4′-b]carbazole

In the title compound, C24H15NO2S2, the ring system composed of the five fused rings is almost planar (r.m.s. deviation for all non-H atoms = 0.056 Å). The dihedral angle between the fused ring system and the phenyl ring is 83.4 (9)°. The crystal packing is stabilized by C—H⋯π and π–π inter­actions between parallel ring systems [centroid–centroid distances = 3.526 (3), 3.877 (3) and 3.712 (3) Å]

Private reputation retrieval in public - a privacy-aware announcement scheme for VANETs

An announcement scheme is a system that facilitates vehicles to broadcast road-related information in vehicular ad hoc networks (VANETs) in order to improve road safety and efficiency. Here, the authors propose a new cryptographic primitive for public updating of reputation score based on the Boneh–Boyen–Shacham short group signature scheme. This allows private reputation score retrieval without a secure channel. Using this, the authors devise a privacy-aware announcement scheme using reputation systems which is reliable, auditable, and robust

3-(4-Methoxy­benz­yl)-2-methyl-1-phenyl­sulfonyl-1H-indole

There are two crystallographically independent mol­ecules in the asymmetric unit of the title compound, C23H21NO3S. The indole ring system is approximately perpendicular to the sulfonyl phenyl ring in both mol­ecules [dihedral angles = 85.42 (8) and 88.30 (9)°]. C—H⋯O inter­actions between mol­ecules stabilize the crystal structure