5,344 research outputs found

    Prevalence and correlates of physical health conditions in Jamaica and Guyana

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    The increasing prevalence of non-communicable diseases remains an important source of concern in the Caribbean and Latin American regions. This study examines rates and the associated socio- demographic correlates of physical health indicators in Jamaica and Guyana. Area probability cross- sectional data were collected on 1,218 Jamaicans and 2,068 Guyanese participants in 2005. Physician- diagnosed hypertension, diabetes mellitus, arthritis, and self-rated oral and general physical health were assessed using descriptive statistics, chi-square, and hierarchical logistic regression analytic procedures. Jamaicans generally reported poorer physical health, including diabetes mellitus, arthritis, and overall perceived oral and physical health compared to Guyanese; Guyanese reported higher rates of hypertension. Generally, lower social and economic standing was associated with poorer health conditions but made different contributions across countries. The study highlights the need for greater awareness and access to health care services for individuals who are especially vulnerable to poorer health. The results of this study suggest the need for additional studies on factors associated with physical health conditions, including a better understanding of the role of race/ethnicity in the Caribbean

    The role of E1-E2 interplay in multiphonon Coulomb excitation

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    In this work we study the problem of a charged particle, bound in a harmonic-oscillator potential, being excited by the Coulomb field from a fast charged projectile. Based on a classical solution to the problem and using the squeezed-state formalism we are able to treat exactly both dipole and quadrupole Coulomb field components. Addressing various transition amplitudes and processes of multiphonon excitation we study different aspects resulting from the interplay between E1 and E2 fields, ranging from classical dynamic polarization effects to questions of quantum interference. We compare exact calculations with approximate methods. Results of this work and the formalism we present can be useful in studies of nuclear reaction physics and in atomic stopping theory.Comment: 10 pages, 6 figure

    Results of the Cooperative Uniform Soybean Tests, 1947 Part I. North Central States

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    United States Department of Agriculture, Agricultural Research Administration; Bureau of Plant Industry, Soils, and Agricultural Engineering, Division of Forage Crops and Diseases Cooperating with State Agricultural Experiment Station

    Psychosocial factors and coronary calcium in adults without clinical cardiovascular disease

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    http://deepblue.lib.umich.edu/bitstream/2027.42/61519/2/Diez Roux 2006, Psychosocial factors and Coronary Calcium in adults without clinical cardiovascular disease.pd

    Improved specificity of gene silencing by siRNAs containing unlocked nucleobase analogs

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    siRNAs confer sequence specific and robust silencing of mRNA. By virtue of these properties, siRNAs have become therapeutic candidates for disease intervention. However, their use as therapeutic agents can be hampered by unintended off-target effects by either or both strands of the siRNA duplex. We report here that unlocked nucleobase analogs (UNAs) confer desirable properties to siRNAs. Addition of a single UNA at the 5′-terminus of the passenger strand blocks participation of the passenger strand in RISC-mediated target down-regulation with a concomitant increase in guide strand activity. Placement of a UNA in the seed region of the guide strand prevents miRNA-like off-target silencing without compromising siRNA activity. Most significantly, combined substitution of UNA at the 3′-termini of both strands, the addition of a UNA at the 5′-terminus of the passenger strand, and a single UNA in the seed region of the guide strand, reduced the global off-target events by more than 10-fold compared to unmodified siRNA. The reduction in off-target events was specific to UNA placement in the siRNA, with no apparent new off-target events. Taken together, these results indicate that when strategically placed, UNA substitutions have important implications for the design of safe and effective siRNA-based therapeutics

    Results of the Cooperative Uniform Soybean Tests, 1948 Part I. North Central States

    Get PDF
    United States Department of Agriculture, Agricultural Research Administration; Bureau of Plant Industry, Soils, and Agricultural Engineering, Division of Forage Crops and Diseases Cooperating with State Agricultural Experiment Station

    Results of the Cooperative Uniform Soybean Tests, 1946 Part I. North Central States

    Get PDF
    United States Department of Agriculture, Agricultural Research Administration; Bureau of Plant Industry, Soils, and Agricultural Engineering, Division of Forage Crops and Diseases Cooperating with State Agricultural Experiment Station

    Results of the Cooperative Uniform Soybean Tests, 1945. Part I. North Central States

    Get PDF
    United States Department of Agriculture Agricultural Research Administration Bureau of Plant Industry, Soils, and Agricultural Engineering, Division of Forage Crops and Diseases Cooperating with State Agricultural Experiment Station
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