304 research outputs found
Mechanical Behaviour of Air-plasma Sprayed Functionally Graded YSZ-Mullite Environmental Barrier Coatings: A Study via Instrumented Indentation
6 páginas, 7 figuras, 1 tabla.-- Comunicación presentada al 33th International Thermal Spray Conference & Exposition 2010; Thermal Spray: Global Solutions for Future Applications.-- et al.Mullite (Al6Si2O13) is the basis of efficient environmental barrier coatings (EBCs) for protecting Si-based ceramic
matrix composites (CMCs) selected to replace specific hot-section metallic components in advanced gas turbines.
Furthermore, YSZ-mullite multilayer architectures with compositional grading between the bond coat and YSZ top
coat were envisioned as solutions to ease their coefficient of thermal expansion (CTE) mismatch induced stress.
Consequently, a proper understanding of the mechanical properties such as the elastic modulus, hardness or
plastic/elastic recovery work serve for an efficient design of such refractory oxide multilayers. In this work, three
different mullite powder morphologies (fused and crushed, spray-dried and freeze-granulated) were employed.
Using depth-sensing indentation with loads in the range 100 – 500 mN, the role of the microstructure and
morphology of the powder feedstock on the mechanical behaviour of air plasma sprayed mullite bond coats
deposited on SiC Hexoloy substrates was investigated. Fully crystalline as-sprayed mullite coatings were
engineered under controlled deposition conditions. Mechanical properties were measured for the as-sprayed
coatings as well as for coatings heat-treated at 1300oC, in water vapour environment, for periods up to 500 h. Both
E and H values of the coatings are found to be highly dependent on the morphology of the starting powders.This work has been
supported by NRC-CSIC program (project
2007CA003).Peer reviewe
Atomic-scale structure of self-assembled In(Ga)As quantum rings in GaAs
We present an atomic-scale analysis of the indium distribution of self-assembled In(Ga)As quantum rings (QRs) which are formed from InAs quantum dots by capping with a thin layer of GaAs and subsequent annealing. We find that the size and shape of QRs as observed by cross-sectional scanning tunneling microscopy (X-STM) deviate substantially from the ring-shaped islands as observed by atomic force microscopy on the surface of uncapped QR structures. We show unambiguously that X-STM images the remaining quantum dot material whereas the AFM images the erupted quantum dot material. The remaining dot material shows an asymmetric indium-rich crater-like shape with a depression rather than an opening at the center and is responsible for the observed electronic properties of QR structures. These quantum craters have an indium concentration of about 55% and a diameter of about 20 nm which is consistent with the observed electronic radius of QR structures.This work was partially supported by the GOA BOF UA 2000, IUAP, FWO-V projects G.0274.01N, G.0435.03, the WOG WO.035.04N (Belgium), the Spanish MCYT under NANOSELF project TIC2002-04096-C03-03 (Spain), the
European Commission GROWTH Programme, NANOMAT
project, contract No. G5RD-CT-2001-00545, and the European Commission SANDiE Network of Excellence, contract No. NMP4-CT-2004-500101.Peer reviewe
Análisis de la sentencia T-629 de 2010 en cuanto al reconocimiento de derechos laborales a trabajadoras sexuales en Colombia
CD-T 344.01 G165;47 p.La presente investigación busca determinar hasta qué punto existe un desconocimiento de los derechos laborales de las trabajadoras sexuales en el paÃs, cuáles son las causas de ese desconocimiento y qué posibles recomendaciones se pueden formular para la solución de esta problemática social.Universidad Libre Seccional Pereir
Development and Validation of Breadcrumbing in Affective-Sexual Relationships (BREAD-ASR) Questionnaire: Introducing a New Online Dating Perpetration
New technologies are changing people’s lifestyles and in turn, their way of relating to and interacting with others. Breadcrumbing is one of the new 2.0 concepts linked to the virtual relationship paradigm. This study aimed to design and psychometrically test the Breadcrumbing in Affective-Sexual Relationships (BREAD-ASR) Questionnaire to explore breadcrumbing perpetration in adolescent relationships online. A total of 247 adolescents participated in a paper-and-pencil survey carried out from March to June 2019 in a high school in southeastern Spain. Psychometric analysis showed a satisfactory content and construct validity for the instrument. The ordinal alpha coefficient was 0.83, indicating the BREAD-ASR questionnaire had good internal consistency. The BREAD-ASR questionnaire constitutes a valid and reliable instrument which can be used by health professionals in screenings for breadcrumbing perpetration and to design effective prevention and intervention programs in the community, which may help and support adolescents and families to deal with new forms of online relationships and perpetration successfully
Seguimiento de las recomendaciones sobre psicofarmacologÃa y su repercusión conductual en la discapacidad intelectual
En la población con discapacidad intelectual -DI- hay una elevada morbilidad psiquiátricaconductual. Se estima que por este motivo entre un tercio y tres cuartos de estas personas reciben antipsicóticos. Existe un consenso de expertos para guiar la toma de decisiones farmacoterapéuticas en estos casos. Su aplicación conseguirÃa una mayor eficacia del tratamiento, reduciendo los problemas conductuales, mejorando las habilidades adaptativas. El ICAP Inventory for client and agency planning es un instrumento para valoración y evaluación de servicios para personas con DI, que incluye escalas para puntuación de problemas conductuales y de conductas adaptativas. Para determinar la asociación entre el seguimiento de las recomendaciones farmacoterapeuticas de los expertos y las puntuaciones de los problemas conductuales y las habilidades adaptativas en un grupo de sujetos con DI, se realizó un estudio observación transversal. El tratamiento farmacológico recibido por cada sujeto de un colectivo de sujetos diagnosticados de DI -CIE-10- se clasificó como conforme o no con las recomendaciones de la guÃa en lo referente a los criterios de indicación, dosis, duración y polifarmacia. Se compararon las puntuaciones de conducta adaptativa y de problemas de conducta del ICAP en función de la conformidad del tratamiento con los criterios. El cumplimiento del criterio de dosis se asoció con mejor conducta adaptativa -p menor que 0,05-, el cumplimiento de los criterios de duración y polifarmacia se asociaron con menores problemas de conducta -p menor que 0,05-. No hubo asociación entre cumplimiento del criterio de indicación con la puntuación de problemas de conducta, ni de las habilidades adaptativas
Building the genomic nation: ‘Homo Brasilis’ and the ‘Genoma Mexicano’ in comparative cultural perspective
This article explores the relationship between genetic research, nationalism and the construction of collective social identities in Latin America. It makes a comparative analysis of two research projects – the ‘Genoma Mexicano’ and the ‘Homo Brasilis’ – both of which sought to establish national and genetic profiles. Both have reproduced and strengthened the idea of their respective nations of focus, incorporating biological elements into debates on social identities. Also, both have placed the unifying figure of the mestizo/mestiço at the heart of national identity constructions, and in so doing have displaced alternative identity categories, such as those based on race. However, having been developed in different national contexts, these projects have had distinct scientific and social trajectories: in Mexico, the genomic mestizo is mobilized mainly in relation to health, while in Brazil the key arena is that of race. We show the importance of the nation as a frame for mobilizing genetic data in public policy debates, and demonstrate how race comes in and out of focus in different Latin American national contexts of genomic research, while never completely disappearing
Protection of Spanish Ibex (Capra pyrenaica) against Bluetongue Virus Serotypes 1 and 8 in a Subclinical Experimental Infection
Many wild ruminants such as Spanish ibex (Capra pyrenaica) are susceptible to Bluetongue virus (BTV) infection, which causes disease mainly in domestic sheep and cattle. Outbreaks involving either BTV serotypes 1 (BTV-1) and 8 (BTV-8) are currently challenging Europe. Inclusion of wildlife vaccination among BTV control measures should be considered in certain species. In the present study, four out of fifteen seronegative Spanish ibexes were immunized with a single dose of inactivated vaccine against BTV-1, four against BTV-8 and seven ibexes were non vaccinated controls. Seven ibexes (four vaccinated and three controls) were inoculated with each BTV serotype. Antibody and IFN-gamma responses were evaluated until 28 days after inoculation (dpi). The vaccinated ibexes showed significant (P<0.05) neutralizing antibody levels after vaccination compared to non vaccinated ibexes. The non vaccinated ibexes remained seronegative until challenge and showed neutralizing antibodies from 7 dpi. BTV RNA was detected in the blood of non vaccinated ibexes from 2 to the end of the study (28 dpi) and in target tissue samples obtained at necropsy (8 and 28 dpi). BTV-1 was successfully isolated on cell culture from blood and target tissues of non vaccinated ibexes. Clinical signs were unapparent and no gross lesions were found at necropsy. Our results show for the first time that Spanish ibex is susceptible and asymptomatic to BTV infection and also that a single dose of vaccine prevents viraemia against BTV-1 and BTV-8 replication
Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population
Neuromyelitis Optica (NMO) is an autoimmune disease with a higher prevalence in non-European populations. Because the Mexican population resulted from the admixture between mainly Native American and European populations, we used genome-wide microarray, HLA high-resolution typing and AQP4 gene sequencing data to analyze genetic ancestry and to seek genetic variants conferring NMO susceptibility in admixed Mexican patients. A total of 164 Mexican NMO patients and 1,208 controls were included. On average, NMO patients had a higher proportion of Native American ancestry than controls (68.1% vs 58.6%; p = 5 × 10–6). GWAS identified a HLA region associated with NMO, led by rs9272219 (OR = 2.48, P = 8 × 10–10). Class II HLA alleles HLA-DQB1*03:01, -DRB1*08:02, -DRB1*16:02, -DRB1*14:06 and -DQB1*04:02 showed the most significant associations with NMO risk. Local ancestry estimates suggest that all the NMO-associated alleles within the HLA region are of Native American origin. No novel or missense variants in the AQP4 gene were found in Mexican patients with NMO or multiple sclerosis. To our knowledge, this is the first study supporting the notion that Native American ancestry significantly contributes to NMO susceptibility in an admixed population, and is consistent with differences in NMO epidemiology in Mexico and Latin America.Fil: Romero Hidalgo, Sandra. Instituto Nacional de Medicina Genómica; MéxicoFil: Flores Rivera, José. Instituto Nacional de NeurologÃa y NeurocirugÃa; MéxicoFil: Rivas Alonso, Verónica. Instituto Nacional de NeurologÃa y NeurocirugÃa; MéxicoFil: Barquera, Rodrigo. Max Planck Institute For The Science Of Human History; Alemania. Instituto Nacional de AntropologÃa e Historia; MéxicoFil: Villarreal Molina, MarÃa Teresa. Instituto Nacional de Medicina Genómica; MéxicoFil: Antuna Puente, Bárbara. Instituto Nacional de Medicina Genómica; MéxicoFil: Macias Kauffer, Luis Rodrigo. Universidad Nacional Autónoma de México; MéxicoFil: Villalobos Comparán, Marisela. Instituto Nacional de Medicina Genómica; MéxicoFil: Ortiz Maldonado, Jair. Instituto Nacional de NeurologÃa y NeurocirugÃa; MéxicoFil: Yu, Neng. American Red Cross; Estados UnidosFil: Lebedeva, Tatiana V.. American Red Cross; Estados UnidosFil: Alosco, Sharon M.. American Red Cross; Estados UnidosFil: GarcÃa RodrÃguez, Juan Daniel. Instituto Nacional de Medicina Genómica; MéxicoFil: González Torres, Carolina. Instituto Nacional de Medicina Genómica; MéxicoFil: Rosas Madrigal, Sandra. Instituto Nacional de Medicina Genómica; MéxicoFil: Ordoñez, Graciela. NeuroimmunologÃa, Instituto Nacional de NeurologÃa y NeurocirugÃa; MéxicoFil: Guerrero Camacho, Jorge Luis. Instituto Nacional de NeurologÃa y NeurocirugÃa; MéxicoFil: Treviño Frenk, Irene. American British Cowdray Medical Center; México. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Escamilla Tilch, Monica. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: GarcÃa Lechuga, Maricela. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Tovar Méndez, VÃctor Hugo. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Pacheco Ubaldo, Hanna. Instituto Nacional de AntropologÃa E Historia. Escuela Nacional de AntropologÃa E Historia; MéxicoFil: Acuña Alonzo, Victor. Instituto Nacional de AntropologÃa E Historia. Escuela Nacional de AntropologÃa E Historia; MéxicoFil: Bortolini, MarÃa Cátira. Universidade Federal do Rio Grande do Sul; BrasilFil: Gallo, Carla. Universidad Peruana Cayetano Heredia; PerúFil: Bedoya BerrÃo, Gabriel. Universidad de Antioquia; ColombiaFil: Rothhammer, Francisco. Universidad de Tarapacá; ChileFil: Gonzalez-Jose, Rolando. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico de Ciencias Sociales y Humanas; ArgentinaFil: Ruiz Linares, Andrés. Colegio Universitario de Londres; Reino UnidoFil: Canizales Quinteros, Samuel. Universidad Nacional Autónoma de México; MéxicoFil: Yunis, Edmond. Dana Farber Cancer Institute; Estados UnidosFil: Granados, Julio. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Corona, Teresa. Instituto Nacional de NeurologÃa y NeurocirugÃa; Méxic
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