60 research outputs found
SUPPRESSION OF SYMPATHETIC NERVOUS FUNCTION IN LOW-RENIN ESSENTIAL HYPERTENSION
Study of general haemodynamics in 15 patients with low-renin essential hypertension showed haemodynamic and pathophysiological heterogeneity. However, there was suppression of sympathetic nervous system function in all low-renin patients, regardless of haemodynamic pattern. Subnormal sympathetic nervous activity was manifested by a low normal mean plasma-noradrenaline concentration at rest, diminished noradrenaline responsiveness to postural stimulation, and a reduced blood-pressure response to the indirectly acting sympathomimetic amine tyramine. It is proposed that the syndrome of low-renin essential hypertension is of diverse aetiology, but with secondary sympathetic nervous system underactivity as a feature common to the various forms. The low plasmarenin activity is probably an expression of defective sympathetic nervous system stimulation of renin release.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/21720/1/0000112.pd
Role of cardiac factors in the initial hypotensive action by beta-adrenoreceptor blocking agents.
Mild exercise decreases plasma endogenous digitalislike substance in hypertensive individuals.
Calcium channel blockade-based antihypertensive treatment regimens on eft ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluating regression of ventricular enlargement (preserve) trial
Reliability of echocardiographic assessment of left ventricular structure and function. The PRESERVE Trial.
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