7 research outputs found
Investigation of segmental reorganization within amphiphilic block polymer nanoparticles derived from shell crosslinked micelle templates: Shell crosslinked knedel‐like inversion
No full textSynthesis of Polymer Nanospheres and Carbon Nanospheres Using the Monomer 1,8-Dihydroxymethyl-1,3,5,7- octatetrayne
No full textDevelopment of poly (acrylamide-co-diallyldimethylammoniumchloride) nanogels and study of their ability as drug delivery devices
No full textRapid Synthesis of Functional Polymer Brushes by Surface-Initiated Atom Transfer Radical Polymerization of an Acidic Monomer
No full textStabilization of amino acid derived diblock copolymer micelles through favorable D:L side chain interactions
No full textOptically pure N-acryloyl-(D)-leucine methyl ester (D-Leu-OMe) (1) and N-acryloyl-(1)-leucine methyl ester (L-Leu-OMe) (2) were synthesized and studied using infrared spectroscopy and melting point analysis to determine if D-L interactions are preferential relative to D-D or L-L interactions. Reversible addition-fragmentation chain transfer (RAFT) polymerization yielded enantiopure homopolymers of D-Leu-OMe (1) and L-Leu-OMe ester (2). The two enantiopure polymers. 5 and 6. and a 1:1 w/w racemic blend of both polymers were studied using infrared spectroscopy to investigate the intermolecular interactions in the polymeric systems. Poly(tert-butyl acrylate) [P('BuA)] macro chain transfer agents were used to synthesize two diblock copolymers from 1 and 2. respectively. Subsequent deprotection of the P('BuA) block to poly(acrylic acid) (PAA) yielded two chiral amphiphilic diblock copolymers. 7 and 8. Both enantiopure polymers were self-assesmbled separately and then in a 1:1 w/w ratio, and the resulting morphologies characterized using dynamic light scattering, atomic force microscopy, transmission electron miroscopy, and circular dichroism
