Design for the distributed data locator service for multi-site data repositories

The Remote Experimentation Centre (REC) in Japan has been preparing to replicate the full dataset of ITER over 10 000 km distance. In such a multi-site data repository environment, the data location informing service will be essential to find and retrieve the data efficiently. Considering the long latency time and the self sustainability of remote sites, the data location database should be running at each repository site. Multi-master asynchronous replication between cooperating databases will be essential to realize the remote experimental collaborations in fusion research. This study has investigated the functional differences of some relational databases and found that Postgres BDR has the expected database replication capabilities. Bi-directional replication (BDR) tests by using the LHD database and SNET revealed that the throughputs are sufficient for remote collaborations in fusion experiments

Design for the distributed data locator service for multi-site data repositories

The Remote Experimentation Centre (REC) in Japan has been preparing to replicate the full dataset of ITER over 10 000 km distance. In such a multi-site data repository environment, the data location informing service will be essential to find and retrieve the data efficiently. Considering the long latency time and the self sustainability of remote sites, the data location database should be running at each repository site. Multi-master asynchronous replication between cooperating databases will be essential to realize the remote experimental collaborations in fusion research. This study has investigated the functional differences of some relational databases and found that Postgres BDR has the expected database replication capabilities. Bi-directional replication (BDR) tests by using the LHD database and SNET revealed that the throughputs are sufficient for remote collaborations in fusion experiments

Vesicular trafficking machinery, the actin cytoskeleton, and H+-K+-ATPase recycling in the gastric parietal cell

Gastric HCl secretion by the parietal cell involves the secretagogue-regulated re-cycling of the H+–K+-ATPase at the apical membrane. The trafficking of the H+–K+-ATPase and the remodelling of the apical membrane during this process are likely to involve the co-ordination of the function of vesicular trafficking machinery and the cytoskeleton. This review summarizes the progress made in the identification and characterization of components of the vesicular trafficking machinery that are associated with the H+–K+-ATPase and of components of the actin-based cytoskeleton that are associated with the apical membrane of the parietal cell. Since many of these proteins are also expressed at the apical pole of other epithelial cells, the parietal cell may represent a model system to characterize the protein- protein interactions that regulate apical membrane trafficking in many other epithelial cells