The Classic: A Morphogenetic Matrix for Differentiation of Bone Tissue

This Classic Article is a reprint of the original work by Marshall R. Urist, A Morphogenetic Matrix for Differentiation of Bone Tissue. An accompanying biographical sketch of Marshall R. Urist, MD is available at DOI 10.1007/s11999-009-1067-4; a second Classic Article is available at DOI 10.1007/s11999-009-1068-3; and a third Classic Article is available at DOI 10.1007/s11999-009-1069-2. The Classic Article is © 1970 by Springer and is reprinted with permission from Urist MR. A morphogenetic matrix for differentiation of bone tissue. Calc Tiss Res. 1970:4(Suppl);98–101

The Classic: Bone Morphogenetic Protein

This Classic Article is a reprint of the original work by Marshall R. Urist and Basil S. Strates, Bone Morphogenetic Protein. An accompanying biographical sketch of Marshall R. Urist, MD is available at DOI 10.1007/s11999-009-1067-4; a second Classic Article is available at DOI 10.1007/s11999-009-1069-2; and a third Classic Article is available at DOI 10.1007/s11999-009-1070-9. The Classic Article is © 1971 by Sage Publications Inc. Journals and is reprinted with permission from Urist MR, Strates BS. Bone morphogenetic protein. J Dent Res. 1971;50:1392–1406

The Classic: A Morphogenetic Matrix for Differentiation of Cartilage in Tissue Culture

This Classic Article is a reprint of the original work by Hiroshi Nogami and Marshall R. Urist, A Morphogenetic Matrix for Differentiation of Cartilage in Tissue Culture. An accompanying biographical sketch of Marshall R. Urist, MD is available at DOI 10.1007/s11999-009-1067-4; a second Classic Article is available at DOI 10.1007/s11999-009-1068-3; and a third Classic Article is available at DOI 10.1007/s11999-009-1070-9. The Classic Article is © 1970 by the Society for Experimental Biology and Medicine and is reprinted with permission from Nogami H, Urist MR. A morphogenetic matrix for differentiation of cartilage in tissue culture. Proc Soc Exp Biol Med. 1970;134;530–535

Natural Sources and Applications of Demineralized Bone Matrix in the Field of Bone and Cartilage Tissue Engineering

none8siDemineralized bone matrix (DBM) is one of the most widely used materials for bone repair. Recently, different strategies in tissue engineering have been used to improve preparation of biomaterials from natural sources suitable for the use in bone regeneration. However, the application of DBM in tissue engineering is still a challenge, because the mechanical properties which are essential to bear tensile and load and the risk of transmission of disease by donor are still a matter of homework. A solution to this problem is to blend natural and synthetic polymers to complement defects and make them ideal biomaterials. An ideal biomaterial improves survival, adhesion, proliferation, induction, and differentiation of cells in the biomaterial after in vivo transplantation. In this review, we will look at the study of DBM made of natural and synthetic materials giving a direction for future research.noneCho, Hunhwi; Bucciarelli, Alessio; Kim, Wonkyung; Jeong, Yongwoon; Kim, Namyeong; Jung, Junjae; Yoon, Sunjung; Khang, GilsonCho, Hunhwi; Bucciarelli, Alessio; Kim, Wonkyung; Jeong, Yongwoon; Kim, Namyeong; Jung, Junjae; Yoon, Sunjung; Khang, Gilso