400 research outputs found

    A Provisional List of the Species of Septoria in Iowa

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    There are over 1,200 species of the genus Septoria, all of them being parasitic. Most of the members of the genus occur on wild hosts, but several of them cause diseases of great importance on cultivated plants

    Response of phytophthora species to physical stimuli and certain organic compounds

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    (Abstract shortened by UMI.

    Community-engaged primary care medical education

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    BACKGROUND: Community-engaged medical education (CEME) requires medical schools to partner with local communities to help address community priorities, whilst enhancing the learning experiences of students. Current literature on CEME has focused on evaluating its effects on students; however, there remains a gap in exploring whether CEME initiatives can have a sustainable impact for communities. APPROACH: The Community Action Project (CAP) at Imperial College London, is an eight-week, community-engaged, quality improvement project for Year 3 medical students. Students initially consult with clinicians, patients and wider community stakeholders to understand local needs and assets, and identify a health priority to address. They then work with relevant stakeholders to design, implement and evaluate a project to help address their identified priority. EVALUATION: All CAPs (n = 264) completed in the 2019-2021 academic years were evaluated for evidence of several key areas, including community engagement and sustainability. 91% of projects evidenced a needs analysis, 71% demonstrated patient involvement in their development, and 64% demonstrated sustainable impacts from their projects. Analysis revealed the topics frequently addressed, and the formats used by students. Two CAPs are described in more detail to demonstrate their community impact. IMPLICATIONS: The CAP demonstrates how the principles of CEME (meaningful community engagement and social accountability) can lead to sustainable benefits for local communities through purposeful collaboration with patients and local communities. Strengths, limitations and future directions are highlighted

    Nonfactorization in Hadronic Two-body Cabibbo-favored decays of D^0 and D^+

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    With the inclusion of nonfactorized amplitudes in a scheme with Nc=3N_c=3, we have studied Cabibbo-favored decays of D0D^0 and D+D^+ into two-body hadronic states involving two isospins in the final state. We have shown that it is possible to understand the measured branching ratios and determined the sizes and signs of nonfactorized amplitudes required.Comment: 15 pages, Late

    Weak radiative hyperon decays, Hara's theorem and the diquark

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    Weak radiative hyperon decays are discussed in the diquark-level approach. It is pointed out that in the general diquark formalism one may reproduce the experimentally suggested pattern of asymmetries, while maintaining Hara's theorem in the SU(3) limit. At present, however, no detailed quark-based model of parity-violating diquark-photon coupling exists that would have the necessary properties.Comment: 10 pages, LaTe

    Obesity and diabetes are major risk factors for epicardial adipose tissue inflammation

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    BACKGROUND: Epicardial adipose tissue (EAT) directly overlies the myocardium, with changes in its morphology and volume associated with myriad cardiovascular and metabolic diseases. However, EAT’s immune structure and cellular characterization remain incompletely described. We aimed to define the immune phenotype of EAT in humans and compare such profiles across lean, obese, and diabetic patients. METHODS: We recruited 152 patients undergoing open-chest coronary artery bypass grafting (CABG), valve repair/replacement (VR) surgery, or combined CABG/VR. Patients’ clinical and biochemical data and EAT, subcutaneous adipose tissue (SAT), and preoperative blood samples were collected. Immune cell profiling was evaluated by flow cytometry and complemented by gene expression studies of immune mediators. Bulk RNA-Seq was performed in EAT across metabolic profiles to assess whole-transcriptome changes observed in lean, obese, and diabetic groups. RESULTS: Flow cytometry analysis demonstrated EAT was highly enriched in adaptive immune (T and B) cells. Although overweight/obese and diabetic patients had similar EAT cellular profiles to lean control patients, the EAT exhibited significantly (P ≤ 0.01) raised expression of immune mediators, including IL-1, IL-6, TNF-α, and IFN-γ. These changes were not observed in SAT or blood. Neither underlying coronary artery disease nor the presence of hypertension significantly altered the immune profiles observed. Bulk RNA-Seq demonstrated significant alterations in metabolic and inflammatory pathways in the EAT of overweight/obese patients compared with lean controls. CONCLUSION: Adaptive immune cells are the predominant immune cell constituent in human EAT and SAT. The presence of underlying cardiometabolic conditions, specifically obesity and diabetes, rather than cardiac disease phenotype appears to alter the inflammatory profile of EAT. Obese states markedly alter EAT metabolic and inflammatory signaling genes, underlining the impact of obesity on the EAT transcriptome profile. FUNDING: Barts Charity MGU0413, Abbott, Medical Research Council MR/T008059/1, and British Heart Foundation FS/13/49/30421 and PG/16/79/32419

    Hyperon weak radiative decays in chiral perturbation theory

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    We investigate the leading-order amplitudes for weak radiative decays of hyperons in chiral perturbation theory. We consistently include contributions from the next-to-leading order weak-interaction Lagrangian. It is shown that due to these terms Hara's theorem is violated. The data for the decays of charged hyperons can be easily accounted for. However, at this order in the chiral expansion, the four amplitudes for the decays of neutral hyperons satisfy relations which are in disagreement with the data. The asymmetry parameters for all the decays can not be accounted for without higher-order terms. We shortly comment on the effect of the 27-plet part of the weak interaction.Comment: 8 pages of REVTeX and using macro-package "feynman.tex" (available at http://xxx.lanl.gov/ftp/hep-ph/papers/macros) for the 2 figure

    Dynamics of coherently pumped lasers with linearly polarized pump and generated fields

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    The influence of light polarization on the dynamics of an optically pumped single-mode laser with a homogeneously broadened four-level medium is theoretically investigated in detail. Pump and laser fields with either parallel or crossed linear polarizations are considered, as are typical in far-infrared-laser experiments. Numerical simulations reveal dramatically different dynamic behaviors for these two polarization configurations. The analysis of the model equations allows us to find the physical origin of both behaviors. In particular, the crossed-polarization configuration is shown to be effective in decoupling the pump and laser fields, thus allowing for the appearance of Lorenz-type dynamics

    A Measurement of the Decay Asymmetry Parameters in \Xi_{c}^{0}\to \X^{-}\pi^{+}

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    Using the CLEO II detector at the Cornell Electron Storage Ring we have measured the Ξc0\Xi_c^{0} decay asymmetry parameter in the decay Ξc0Ξπ+\Xi_c^{0} \to \Xi^{-} \pi^+. We find αΞc0αΞ=0.26±0.18(stat)0.04+0.05(syst)\alpha_{\Xi_c^{0}} \alpha_{\Xi} = 0.26 \pm 0.18{(stat)}^{+0.05}_{-0.04}{(syst)}, using the world average value of αΞ=0.456±0.014\alpha_{\Xi} = -0.456 \pm 0.014 we obtain αΞc0=0.56±0.39(stat)0.09+0.10(syst)\alpha_{\Xi_c^{0}} = -0.56 \pm 0.39{(stat)}^{+0.10}_{-0.09}{(syst)}. The physically allowed range of a decay asymmetry parameter is 1<α<+1-1<\alpha<+1. Our result prefers a negative value: αΞc0\alpha_{\Xi_c^{0}} is <0.1<0.1 at the 90% CL. The central value occupies the middle of the theoretically expected range but is not yet precise enough to choose between models.Comment: 10 pages postscript, also available through http://w4.lns.cornell.edu/public/CLN
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