3 research outputs found
Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases
- Author
- Agache Ioana
- Ageing at Coimbra EIP-AHA Reference Site
- Agostino Gemelli University Hospital Foundation IRCCS
- Ain Shams University
- Ajou University
- Akdis Cezmi
- Akdis Cezmi A.
- Allergy and Asthma Associates of Southern California
- Allergy and Asthma Center Westend
- Allergy and Asthma Medical Group and Research Center
- Amsterdam UMC
- Annesi-Maesano Isabella
- Annesi-Maesano Isabella
- Ansotegui Ignacio J.
- Anto Josep M.
- AQuAS
- Archbishop Makarios III Hospital
- Argentine Association of Allergy and Clinical Immunology
- Arnavielhe Sylvie
- ASA-Advanced Solutions Accelerator
- Assistance publique â HĂŽpitaux de Paris
- Association Asthme et Allergie
- Association of Finnish Pharmacists
- Asthma UK
- Athens Chest Hospital
- August Pi i Sunyer Biomedical Research Institute
- Azienda Ospedaliera di Padova
- Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli
- Azienda Ospedaliera Santa Maria Nuova di Reggio Emilia
- Bachert Claus
- Barcelona Institute for Global Health (ISGlobal)
- Basagana Xavier
- Bateman Eric
- Bateman Eric
- Becker Sven
- Bedbrook Anna
- Bedolla-Barajas Martin
- Bennoor K.S.
- Benveniste Samuel
- Bergmann Karl C.
- Berlin Institute of Health
- Bewick Michael
- Bewick Michael
- Bialek Slawomir
- Billo Nils
- Bilun GemicioÄlu
- Bindslev-Jensen Carsten
- Bindslev-Jensen Carsten
- Bjermer Leif
- Blain Hubert
- Bonini Mateo
- Bonniaud Philippe
- Bosnic-Anticevich Sinthia
- Bosse Isabelle
- Bouchard Jacques
- Boulet Louis P.
- Bourrez Jean Marc
- Bousquet J. Jean
- Briedis Vitalis
- Brightling Christofer E.
- Brozek Jan
- Brozek Jan
- Brusselle Guy
- Brusselle Guy
- Buhl Roland
- Buhl Roland
- Bull DSAS
- Buonaiuto Roland
- Canonica Giorgo W.
- Capital Medical University
- Cardona Victoria
- Cardona Victoria
- Carlsen Karin Lodrup
- Carr Warner
- Carriazo Ana M.
- Cartier Christine
- Casale Thomas
- Casale Thomas
- Catholic University of the Sacred Heart
- Cecchi Lorenzo
- Center for Allergy and Immunology
- Center for Rhinology and Allergology
- Centich: Centre d'Expertise National des Technologies de l'Information et de la communication pour l'autonomie
- Centre for Empowering Patients and Communities
- Centre Hospitalier Universitaire de Québec
- Centre Hospitalier Universitaire PĂ©diatrique Charles de Gaulle
- Centre Hospitalier Universitaire UCLouvain Namur
- Centro de Investigación Biomédica en Red (CIBER)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES)
- Cepeda Sarabia Alfonso M.
- CharitĂ© â UniversitĂ€tsmedizin Berlin
- Charles University
- Charles University
- Chavannes Niels
- Chiba University
- Chiba University Hospital
- Children's Hospital Srebrnjak
- Chkhartishvili Eka
- CHU & University LiĂšge Domaine L Sart-Tilman BĂąt B35
- CHU Montpellier
- Chu Derek K.
- Cingi Cemal
- CNRS
- Colgan Elaine
- Consortium of Pharmacies and Services COSAFER
- Costa Elisio
- Courbis Anne Lise
- CRI-Clinical Research International-Ltd
- Croatian Pulmonary Society
- Cruz Alvaro
- Cruz Alvaro A.
- CUF-Porto Hospital and Institute
- Custovic Adnan
- Cvetkosvki Biljana
- Cyprus University of Technology
- Czarlewski Wienczyslawa
- CĂĄritas Diocesana de Coimbra
- Da Silva Jane
- Damato Gennaro
- Danish Commitee for Health Education
- Dantas Carina
- Dauvilliers Yves
- David Tvildiani Medical University
- De Feo Giulia
- de l'Industrie et du Numérique
- De Manuel Keenoy Esteban
- De Sousa Jaime Correia
- Dedeu Antoni
- Department of Health Social Services and Public Safety
- Devillier Philippe
- Di Capua Stefania
- Diaz Sandra GonzĂĄlez
- Die Hautambulanz and Rothhaar study center
- Dirceu Solé
- Dokic Dejand
- Dubai Hospital
- Dubakiene Ruta
- Dykewickz Marc
- DâAmato Gennaro
- Ebisawa Motohiro
- EFA European Federation of Allergy and Airways Diseases Patients' Associations
- EIT Health France
- El-Gamal Yaya
- Eller Esben
- Emek Medical Center
- Emuzyte Regina
- Epidemiology
- Erasmus University Rotterdam
- Erhola Marina
- EUREGHA European Regional and Local Health Association
- Euro-Asian Respiratory Society
- European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA)
- European Health Futures Forum (EHFF)
- Faculdade de Medicina de Lisboa
- Farmacias Holon
- Farmacie Dei Golfi Group
- Farrell John
- Federico II University Hospital Naples
- FILHA Finnish Lung Association
- Fink-Wagner Antjie
- Fiocchi Alessandro
- Fokkens Wytske J.
- Fonseca Joao A.
- Fontaine Jean F.
- FundaciĂłn ClĂnica MĂ©dica Sur
- Gaga Mina
- Gailen Marshall
- Gamkrelidze Amiran
- Garcia-Aymerich Judith
- Garcia-Aymerich Judith
- Gemicioǧlu Bilun
- Georgian Association of Allergology and Clinical Immunology
- Ghent University
- Global Allergy and Airways Patient Platform GAAPP
- Global Alliance Against Chronic Respiratory Diseases (WHO GARD)
- Gomez Maximiliano
- Gotua Maia
- Guangzhou Medical College
- Guldemond Nick A.
- GuzmĂĄn Maria-Antonieta
- Haahtela Tari
- Hacettepe University
- Hae-Sim Park
- Hajjam Jawad
- Hallym University
- Hallym University College of Medicine
- Health Services Management & Organisation (HSMO)
- Heinrich Heine University DĂŒsseldorf
- Hellings Peter
- Hellings Peter W.
- Hospital ClĂnic de Barcelona
- Hospital CUF-Descobertas
- Hospital del Mar
- Hospital of the Hospitaller Brothers in Buda
- Hospital Quironsalud Bizkaia
- Hospital San Bernardo
- Hospital Vall d'Hebron & ARADyAL research network
- Humanitas University
- Humbert Marc
- Humbert Marc
- Humboldt University of Berlin
- HĂŽpital Foch
- Iaccarino Guido
- Iaccarino Guido
- Ierodiakonou Despo
- Illario Maddalena
- Immunology and Respiratory Diseases
- Imperial College London
- Inserm U1061
- Institut Mines-Télécom
- Institut national de la santé et de la recherche médicale
- Institut Pasteur Paris
- Institute of Biomedicine and Molecular Immunology âA Monroyâ (CNR-IBIM)
- Institute of Legal Informatics and Judicial Systems (IGSiG-CNR)
- International Centre of Excellence in Chronicity Research Barakaldo
- International Primary Care Respiratory Group IPCRG
- iQ4U Consultants Ltd
- IRCCS Azienda UnitĂ Sanitaria Locale di Reggio Emilia
- IRCCS Istituto Clinico Humanitas - Rozzano (Milano)
- IRCCS Oasi Maria SS. - Troina (EN)
- IRCCS Ospedale pediatrico Bambino GesĂč - Roma
- Istanbul University - CerrahpaĆa
- Ivancevich Juan C.
- Johannes Gutenberg University Mainz
- Johns Hopkins University
- Joos Guy
- Joos Guy
- Josip Juraj Strossmayer University of Osijek
- Juan-Carlos Sisul
- Jung Ki-Suck
- Jutel Marek
- Kaidashev Igor
- Kalayci Omer
- Kardas Przemyslaw
- Karolinska Institutet
- Karolinska University Hospital
- Keil Thomas
- Keil Thomas
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- Ki-Suck Jung
- Kleij Rianne
- Kleine-Tebbe Jorg
- Klimek Ludger
- Kowalski Marek L.
- Kritikos Vicky
- KU Leuven
- Kull Inger
- Kuna Piotr
- Kvedariene Violeta
- KYomed INNOV
- Laboratory of Molecular immunology
- Larenas-Linnemann Desiree
- Laune Daniel
- Lda (MEDIDA)
- Le L.T.T.
- Leiden University Medical Center
- Leonardini Lisa
- Lieberman Philip
- Lipworth Brian
- Lithuanian University of Health Sciences
- Lodrup Carlsen Karin C.
- Louis Renaud
- Louis Renaud
- Loureiro Claudia C.
- Lourenço Olga M.
- Lund University
- MACVIA-France and CHU
- Mahboub Bassam
- Mair Alpana
- Malva Joao
- Manisa Celal Bayar University
- Manisa Celal Bayar University School of Medicine
- Manning Patrick
- Marien Gert
- Marshall Gailen D.
- Masjedi Mohamed R.
- Maspero Jorge F.
- Mathieu-Dupas Eve
- Matricardi Poalo M.
- Mattone Internazionale Program
- McMaster University
- Medical Consulting Czarlewski
- Medical University of Graz
- Medical University of Vienna
- Medical University of Warsaw
- Medical University of ĆĂłdĆș
- Medical University Sofia
- Medicine Department HĂŽpital de la Malbaie
- MedScript Ltd.
- Melo-Gomes Elisabete
- Meltzer Eli O.
- Melén Eric
- Menditto Enrica
- Mercier Jacques
- Metropolitan University
- Miculinic Neven
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- Moda Giuliana
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- Mohammad Yousser
- Monash University
- Montefort Steve
- Monti Ricardo
- Morais-Almeida Mario
- Morais-Almeida Mario
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- Municipal Institute for Medical Research Hospital del Mar
- Municipality Pharmacy
- Muraro Antonella
- Murray Ruth
- Mösges Ralf
- MĂŒnter Lars
- Naclerio Robert
- Naclerio Robert
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- Napoli Luigi
- National and Kapodistrian University of Athens
- National Center for Disease Control and Public Health of Georgia
- National Health Service in the UK
- National Hospital Organization Sagamihara National Hospital
- National Hospital Organization Tokyo National Hospital
- National Institute for Health and Welfare
- National Institute of Diseases of the Chest and Hospital
- National Institute of Pneumology M Nasta
- National Institutes of Health
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- National University of Singapore
- Neffen Hugo
- Nekam Kristoff
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- Ninewells Hospital
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- Oslo University Hospital
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- Panzner Peter
- Papadopoulos Nikos
- Papadopoulos Nikos
- Park Hae-Sim
- Paulino Ema
- Pereira Ana-Maria
- Pfaar Oliver
- Pfaar Oliver
- Pham-Thi NhĂąn
- Phillips Jim
- Picard Robert
- Pinnock Hilary
- Plavec Davor
- Pompeu Fabra University
- PontifĂcia Universidade CatĂłlica do ParanĂĄ
- Popov Ted
- Popov Ted A.
- Portejoie Fabienne
- Price David
- Price David
- Prokopakis Emmanuel P.
- Przemyslaw Kardas
- Pugin Benoit
- PĂ©pin Jean-Louis
- Raciborski Filip
- Rajabian-Söderlund Rojin
- Rashid Hospital
- Regional Ministry of Health of Andalusia
- Regione Piemonte
- Reitsma Sietze
- Research in Real-Life
- RNSA (RĂ©seau National de Surveillance AĂ©robiologique)
- Roche Nicolas
- Roche Nicolas
- Rodo Xavier
- Rodo Xavier
- Rolland Christine
- Roller-Wirnsberger Regina E.
- Romano Antonino
- Romano Antonino
- Rosario Nelson
- Rottem Menahenm
- Royal Brompton and Harefield NHS Foundation Trust
- Royal College of Surgeons in Ireland
- Royal Manchester Children's Hospital
- Russian Academy of Medical Sciences
- Russian Ministry of Health
- Ryan Dermot
- Sagamihara National Hospital
- Saint Louis University School of Medicine
- SalimÀki Johanna
- Samolinski Boleslaw
- Sanchez-Borges Mario M.
- Sarabia Alfonso Cepeda
- Schmid-Grendelmeir Peter
- SchĂŒnemann Holger
- SchĂŒnemann Holger J.
- Sciences Po
- Scottish Government
- Sechenov First Moscow State Medical University
- Servicio de Alergia e Immunologia Clinica Santa Isabel
- Sheikh Aziz
- Sheikh Aziz
- Silva Jane
- Sinthia Bosnic-Anticevich
- Sisul Juan-Carlos
- Skin and Allergy Hospital
- SLaai Sociedad Lati-noamericana de Allergia, Asma e Immunologia
- Sociedad Paraguaya de Alergia Asma e Inmunologı'a
- Solé Dirceu
- Somekh David
- Sooronbaev Talant
- Sorbonne Université
- Sousa Jaime
- South African Medical Research Council
- Sova Milan
- Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP)
- Spranger Otto
- SS Cyril and Methodius University in Skopje
- Stellato Cristina
- Stelmach Rafael
- Swiss Institute of Allergy and Asthma Research
- Syrian Private University
- Södersjukhuset
- Talant Sooronbaev
- Termofscher Scientific
- The Allergy and Asthma Institute
- The First Affiliated Hospital of Guangzhou Medical University
- The University of Sydney
- Thiago University Hospital
- Thibaudon Michel
- Tishreen University
- To Teresa
- To Teresa
- Tobacco Control Research Centre
- Todo-Bom Ana
- Togias Alkis
- Tomazic Peter V.
- Toppila-Salmi Sanna
- Transilvania University of Brasov
- Trinidad and ClĂnica El Avila
- Tsiligianni Ioanna
- Ukrainina Medical Stomatological Academy
- Ulrik Charlotte Suppli
- UNC Eshelman School of Pharmacy
- Universidad Autonoma de Nuevo Leon
- Universidad CatĂłlica de CĂłrdoba
- Universidad de Chile
- Universidad de Guadalajara
- Universidad SimĂłn BolĂvar
- Universidade de SĂŁo Paulo
- Universidade Federal da Bahia
- Universidade Federal de SĂŁo Paulo
- University Hospital Center of Porto
- University Hospital Marburg
- University Hospital of South Manchester
- University Hospital Olomouc
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- University Hospital âSv Ivan Rilskiâ
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- University Hospitals of Leicester NHS Trust
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- University of Bari Medical School
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- University of Crete School of Medicine
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- University of Malta
- University of Manchester
- University of Medicine and Pharmacy at Ho Chi Minh City
- University of Minho
- University of Mississippi
- University of Mississippi Medical Center
- University of Naples Federico II
- University of North Carolina at Chapel Hill
- University of Oslo
- University of Oslo Faculty of Medicine
- University of Porto
- University of Salerno
- University of South Florida
- University of Sydney and Woolcock Emphysema Centre and Sydney Local Health District
- University of Tennessee College of Medicine Memphis
- University of Tennessee Health Science Center
- University of Toronto
- University of Turin
- University of Turku
- University of WĂŒrzburg
- University of Zurich
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- Université Paris-Saclay
- Université Versailles St-Quentin-en-Yvelines
- Uppsala University
- USL Toscana Centro
- Valenta Rudolph
- Valentin-Rostan Marylin
- Valero Antonio
- Valero Antonio A.
- Valiulis Arunas
- Valovirta Erkka
- Van Der Kleij Rianne
- Vandenplas Olivier
- Vasankari Tuula
- Ventura Maria-Teresa
- Vezzani Giorgio
- Viart Frédéric
- Viegi Giovanni
- Vilnius University
- Wagenmann Martin
- Walker Samantha
- Wallace Dana
- Wallace Dana
- Wang De Y.
- Waserman Susan
- WHO GARD Planning Group
- Wickman Magnus
- Williams Dennis M.
- Williams Sian
- Wong Gary
- Wong Gary
- Woolcock Emphysema Centre
- Woolcock Institute of Medical Research
- Wroczynski Piotr
- WrocĆaw Medical University
- Yiallouros Panayiotis K.
- Yong Loo Lin School of Medicine
- Yorgancioglu Arzu
- Yorgancioglu Arzu
- Yousser Mohammad
- Yusuf Osman M.
- Zar Heahter J.
- Zeng Stéphane
- Zernotti Mario
- Zhang Luo
- Zhong Nan S.
- Zidarn Mihaela
- Zuberbier Torsten
- Zuberbier Torsten
- Publication venue
- figshare
- Publication date
- 01/01/2019
- Field of study
Abstract Background In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted âpatient activationâ, (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG SantĂ© as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement
Intravenous immunoglobulin treatment for mild Guillain-Barré syndrome. An international observational study
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- 2. Erasmus MC
- 2. KU Leuven
- 2. National and Kapodistrian University of Athens
- A. Davidson
- A. Doets
- A. Echaniz-Laguna
- A. J. van der Kooi
- A. Kohler
- A. Magot
- A. Pardal
- A. Savransky
- A. Schenone
- A. Spyropoulos (Royal Victoria Infirmary
- Aarhus Denmark)
- Aarhus Denmark)
- Allentown USA)
- Amsterdam
- Amsterdam
- Argentina)
- Argentina)
- Argentina)
- Argentina)
- Argentina)
- Argentina)
- Argentina)
- Asturias Spain)
- Athens Greece)
- b) Dhaka
- b) Dhaka
- b) Dhaka
- B. Islam
- B. Stein
- B. van den Berg
- Baltimore USA)
- Bangladesh (icddr
- Bangladesh (icddr
- Bangladesh (icddr
- Bangladesh)
- Bangladesh)
- Bangladesh)
- Barcelona Spain)
- Barcelona Spain)
- Barcelona Spain)
- Barcelona Spain)
- Barcelona Spain)
- Barcelona Spain)
- Barroso F.
- Binda D.
- Bradford UK)
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Burlington
- Burlington VT
- C. Briani
- C. Bunschoten
- C. C. Chao
- C. Casasnovas
- C. Dornonville de la Cour
- C. Fokke
- C. G. Faber
- C. Homedes
- C. J. Gijsbers
- C. J. McDermott
- C. L. Sommer
- C. MĂĄrquez Infante
- C. Nascimbene
- C. Y. Tan
- Calgary Canada)
- Cambridge UK)
- Canada)
- Cape Town
- Cape Town
- Cavaletti G.
- Center
- Charlottesville USA)
- Chiba Japan)
- Chicago USA)
- Columbus USA)
- Copenhagen Denmark)
- Cordoba Spain)
- Cornblath D. R.
- Delft
- Department of Medicine
- Department of Medicine
- Dhaka Bangladesh)
- DO (Lehigh Valley Health Network
- DO (Spectrum Health System
- Dordrecht
- Dordrecht
- E. Dardiotis
- E. H. Niks
- E. Lee Pan
- E. Martinez Hernandez
- E. Nobile Orazio
- F. Eftimov
- F. Vermeij
- Faculty of Medicine
- Faculty of Medicine
- Fayetteville USA)
- FLENI
- France)
- France)
- FRCP (Ipswich Hospital
- FRCP (The Walton Centre
- G. A. Marfia
- G. Antonini
- G. Chavada
- G. Gutiérrez-Gutiérrez
- G. M. Sachs
- G. Mataluni
- G. Meekins
- G. MorĂs de la Tassa
- G. W. van Dijk
- Galassi G.
- Genetics and Maternal and Infantile Sciences (DINOGMI)
- Genova
- Genova Italy)
- Glasgow UK)
- Glasgow UK)
- Glasgow UK)
- Glostrup Denmark)
- Gorson K. C.
- Grand Rapids
- H. D. Katzberg
- H. J. Willison
- H. Kerkhoff
- H. Manji
- H. Tankisi
- Harbo T.
- Helmond and Deurne
- Homburg Germany)
- Homburg Germany)
- Hoorn
- Hospital Clinic
- Hospital of Larissa
- Houston USA)
- Hughes R. A. C.
- Humanitas Clinicala and Research Institute Milan
- Humanitas Clinicala and Research Institute Milan
- I. Illa
- I. Jahan
- I. JericĂł Pascual
- I. R. Bella
- I. Rojas-Marcos
- Indianapolis USA)
- Ipswich UK)
- Irvine USA)
- Italy 2. IRCCS Policlinico San Martino
- Italy)
- Italy)
- Italy)
- Italy)
- J. A. L. Miller
- J. BuÌrmann
- J. D. Varrato
- J. Fehmi (University of Oxford E. A. Fulgenzi
- J. Gilhuis
- J. K. L. Holt
- J. M. Gilchrist
- J. M. Goldstein
- J. Pardo Fernandez (Hospital ClĂnico de Santiago
- J. Roodbol
- J. S. Cosgrove
- J. V. Holbech
- J. Y. Kwan
- Jacksonville USA)
- Jacobs B. C. H. Andersen
- K. Bateman
- K. G. Claeys
- K. Jellema
- K. Kaida
- K. Kimpinski
- K. Kuitwaard
- K. Sheikh
- Kansas City
- Kusunoki S.
- Kuwabara S.
- L. Benedetti
- L. H. Visser
- L. Kiers
- L. Landschoff Lassen
- L. MartĂn-Aguilar
- L. Querol Gutierrez
- L. Santoro
- L. Schwindling
- L. Zhou
- La Spezia
- La Spezia
- Larissa Greece)
- Leeds UK)
- Lehmann H. C.
- Leiden
- Leiden
- Leuven Belgium
- Leuven Belgium)
- Leuven Belgium)
- Leuven Belgium)
- LHSC London-Ontario
- Liverpool UK)
- London UK)
- London UK)
- Lunn M. P.
- M. Bianco (Milan University
- M. Busby
- M. C. Dalakas
- M. Derejko
- M. E. Conti
- M. G. Mattiazzi
- M. Htut
- M. J. Sedano Tous
- M. Kuwahara
- M. M. Dimachkie
- M. Mandarakas
- M. Osei-Bonsu
- M. P. J. Garssen
- M. Pulley
- M. S. Monges
- M. Samukawa
- M. V. Vytopil
- M. van Woerkom (Erasmus MC
- Maastricht
- Malaya)
- Malaya)
- Marseille France)
- MBChB
- MBChB (Groote Schuur Hospital
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- MD (Addenbrookeâs Hospital Cambridge
- MD (Barrow Neurology Clinics
- MD (Bellvitge University Hospital - IDIBELL Neurometabolic Diseases Group. CIBERER
- MD (BicĂȘtre University Hospital
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- MD (Instituto de Investigaciones NeurolĂłgicas RaĂșl Carrea
- MD (Leeds General Infirmary
- MD (Leeds General Infirmary
- MD (Maasstad Hospital
- MD (Mental Health and Sensory Organs (NESMOS)
- MD (Montefiore Medical
- MD (National Hospital Copenhagen
- MD (Neurological Clinic
- MD (Neurology Unit
- MD (Northwestern University Feinberg
- MD (Odense University Hospital
- MD (Ospedale Santâ Andrea La Spezia
- MD (Pinderfields Hospital
- MD (Reference Centre for NMD
- MD (Royal Hallamshire Hospital
- MD (Scientific Institute San Raffaele
- MD (Soulthern Illinois University School of Medicine
- MD (St. Georgeâs Hospital
- MD (St. Josephâs Regional Medical Center
- MD (The University of Tennessee Health Science Center (UTHSC)
- MD (Toho University Medical Center
- MD (University Hospital
- MD (University Hospital Clinicas
- MD (University Hospital/ University of Texas Health Science Center
- MD (University of Arkansas
- MD (University of Calgary
- MD (University of California
- MD (University of Florida
- MD (University of Glasgow
- MD (University of Indiana School of Medicine
- MD (University of Kansas Medical Center
- MD (University of Maryland School of Medicine
- MD (University of Mass Medical School
- MD (University of Melbourne
- MD (University of Minnesota
- MD (University of Padova
- MD (University of Rhode Island
- MD (University of Thessaly
- MD (University of Toronto
- MD (University of Utah School of Medicine
- MD (University of Vermont
- MD (University of Vermont Medical Center
- MD (University of Virginia
- MD (UniversitÀtsklinikum des Saarlandes
- MD (UniversitÀtsklinikum des Saarlandes
- MD (UniversitĂ€tsklinikum WuÌrzburg
- MD (Vlietland Hospital
- MD (Westfriesgasthuis
- MD (Wexner Medical Center at The Ohio State University
- MD (Yale University School of Medicine
- MD (Yale University School of Medicine
- Memphis USA)
- Middlesbrough UK)
- Milan Italy)
- Milan Italy)
- MRCP (Neurology Unit
- N. A. Goyal
- N. J. Silvestri
- N. Kokubun
- N. Kolb
- N. Shahrizaila
- Nantes University Hospital
- Nantes University Hospital
- Napels Italy)
- New Brunswick
- New Haven
- New Haven
- New York
- New York City
- Newcastle UK)
- Newcastle UK)
- NIHR Clinical
- Nijmegen
- Odense Denmark)
- Odense Denmark)
- Odense Denmark)
- Osaka Japan)
- Osaka Japan)
- P. Twydell
- P. Van Damme
- P. Van den Bergh
- Padova Italy)
- Pamplona Spain)
- Paris France)
- Parkville Australia)
- Paterson USA)
- PhD
- PhD (1. Albert Schweitzer Hospital
- PhD (1. Department of Neurosciences
- PhD (1. University Hospitals Leuven
- PhD (Aarhus University Hospital
- PhD (Aarhus University Hospital
- PhD (Albert Schweitzer Hospital
- PhD (Amsterdam University Medical Centre
- PhD (Amsterdam University Medical Centre
- PhD (Bellvitge University Hospital - IDIBELL Neurometabolic Diseases Group. CIBERER
- PhD (Chiba University
- PhD (CHU Timone
- PhD (Complejo Hospitalario de Navarra
- PhD (Concord Repatriation General Hospital
- PhD (Elisabeth-TweeSteden Hospital
- PhD (Elkerliek Hospital
- PhD (Erasmus University Medical Centre
- PhD (Glasgow University
- PhD (Groote Schuur Hospital
- PhD (Haaglanden Medisch Centrum
- PhD (HagaZiekenhuis
- PhD (Hospital de la Santa Creu i Sant Pau
- PhD (Hospital de la Santa Creu i Sant Pau
- PhD (Hospital de PediatrĂa J. P. Garrahan
- PhD (Icahn School
- PhD (International Centre for Diarrhoeal Disease Research
- PhD (International Centre for Diarrhoeal Disease Research
- PhD (James Cook University Hospital
- PhD (Jeroen Bosch Hospital
- PhD (Kindai University
- PhD (Kindai University
- PhD (Kingâs College Hospital
- PhD (Leiden University Medical Centre
- PhD (Leiden University Medical Centre
- PhD (Luigi Sacco Hospital
- PhD (Maastricht University Medical Centre
- PhD (Milan University
- PhD (National Defense Medical College
- PhD (National Institute of Neurosciences and Hospital
- PhD (National Taiwan University Hospital
- PhD (National Taiwan University Hospital
- PhD (Neurological Clinic
- PhD (Odense University Hospital
- PhD (Odense University Hospital
- PhD (Ospedale Santâ Andrea La Spezia
- PhD (Reference Centre for NMD
- PhD (Reinier de Graaf Gasthuis
- PhD (Royal Victoria Infirmary
- PhD (Rutgers
- PhD (The University of Texas Health Science Center at Houston
- PhD (Tufts University School of Medicine Lahey Hospital P. W. Wirtz
- PhD (University Clinic St. Luc
- PhD (University Federico II
- PhD (University Hospital Leuven
- PhD (University of Glasgow
- PhD (University of Oxford J. P. A. Samijn
- PhD candidate (Erasmus University Medical Centre
- PhD candidate (Erasmus University Medical Centre
- PhD candidate (Erasmus University Medical Centre
- PhD candidate (Erasmus University Medical Centre
- PhD candidate (International Centre for Diarrhoeal Disease Research
- Philadelphia USA
- Phoenix Arizona
- Policlinico Tor Vergata
- Policlinico Tor Vergata
- Providence USA)
- Q. D. Mohammad
- R. Bhavaraju-Sanka
- R. C. Roberts
- R. D. M. Hadden
- R. Fazio
- R. J. Nowak
- R. M. Pascuzzi
- R. van Koningsveld
- Rehabilitation Ophthalmology
- Reisin R. C.
- Robert Wood Johnson University Hospital
- Rome Italy)
- Rome Italy)
- Rome Italy)
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Royal Melbourne Hospital
- S. A. Rudnicki
- S. Ajroud-Driss
- S. Attarian
- S. Butterworth
- S. Chen
- S. E. Leonhard
- S. Grisanti
- S. Karafiath
- S. Rinaldi
- S. S. Ladha
- S. T. Hsieh
- S. W. Reddel
- Saitama Japan)
- Salt Lake City
- San Antonio Texas
- San Sebastian
- Santander Cantabria
- Santiago de Compostela (A Coruña)
- Santiago de Compostela (A Coruña)
- SantâAndrea Hospital
- Sapienza University
- Schiedam
- Seville Spain)
- Sheffield UK)
- South-Africa)
- South-Africa)
- Spain)
- Spain)
- Spain)
- Spain)
- Springfield USA)
- Sydney Australia)
- T. E. Bertorini
- T. E. Feasby
- T. Fujioka
- T. GarcĂa-Sobrino
- T. H. Brannagan
- T. van der Ree
- Taipei Taiwan)
- Taipei Taiwan)
- The Hague
- The Hague
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- the Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- the Netherlands)
- the Netherlands)
- The Netherlands)
- the Netherlands)
- The Netherlands)
- the Netherlands)
- Tilburg and Waalwijk
- Tochigi Japan)
- Tokyo Japan)
- Toronto Canada)
- U. A. Badrising
- Universitat AutĂČnoma de Barcelona
- Universitat AutĂČnoma de Barcelona
- Universitat AutĂČnoma de Barcelona
- University of Genova
- University of Malaya
- University of Malaya
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA). Other collaborators were:J. M. Addington
- V. Granit
- V. Lawson
- Van Doorn P. A.
- Verboon C.
- W. Waheed
- Wakefield UK)
- Worcester USA)
- WuÌrzburg Germany)
- Y. Péréon
- Y. Sekiguchi
- Z. Islam
- Zutphen and Apeldoorn
- âs Hertogenbosch
- Publication venue
- 'BMJ'
- Publication date
- 01/01/2021
- Field of study
Objective: To compare the disease course in patients with mild Guillain-Barré syndrome (GBS) who were treated with intravenous immunoglobulin (IVIg) or supportive care only. Methods: We selected patients from the prospective observational International GBS Outcome Study (IGOS) who were able to walk independently at study entry (mild GBS), treated with one IVIg course or supportive care. The primary endpoint was the GBS disability score four weeks after study entry, assessed by multivariable ordinal regression analysis. Results: Of 188 eligible patients, 148 (79%) were treated with IVIg and 40 (21%) with supportive care. The IVIg group was more disabled at baseline. IVIg treatment was not associated with lower GBS disability scores at 4 weeks (adjusted OR (aOR) 1.62, 95% CI 0.63 to 4.13). Nearly all secondary endpoints showed no benefit from IVIg, although the time to regain full muscle strength was shorter (28 vs 56 days, p=0.03) and reported pain at 26 weeks was lower (n=26/121, 22% vs n=12/30, 40%, p=0.04) in the IVIg treated patients. In the subanalysis with persistent mild GBS in the first 2 weeks, the aOR for a lower GBS disability score at 4 weeks was 2.32 (95% CI 0.76 to 7.13). At 1 year, 40% of all patients had residual symptoms. Conclusion: In patients with mild GBS, one course of IVIg did not improve the overall disease course. The certainty of this conclusion is limited by confounding factors, selection bias and wide confidence limits. Residual symptoms were often present after one year, indicating the need for better treatments in mild GBS
Second IVIg course in Guillain-Barré syndrome with poor prognosis. The non-randomised ISID study
- Author
- 0:1â9. doi:10. 1136/jnnp-2019-321496 Neuromuscular Ajroud-Driss
- 2. KU Leuven
- 2. National and Kapodistrian University of Athens
- 2019 at Uppsala Universitet BIBSAM http://jnnp. bmj. com/ J Neurol Neurosurg Psychiatry: first published as 10. 1136/jnnp-2019-321496 on 5 October 2019. Downloaded from 8 Verboon C
- A. Davidson
- A. Doets
- A. Echaniz-Laguna
- A. Grapperon
- A. J. van der Kooi
- A. Schenone
- Allentown USA)
- Amsterdam
- Amsterdam
- Argentina)
- Argentina)
- Argentina)
- Argentina)
- Argentina)
- Argentina)
- Asturias Spain)
- Athens Greece)
- b) Dhaka
- B. C. Kieseier
- B. Islam
- B. Stein
- Baltimore USA)
- Bangladesh (icddr
- Bangladesh)
- Barcelona Spain)
- Barcelona Spain)
- Barcelona Spain)
- Barcelona Spain)
- Bateman K.
- Birmingham UK)
- Bradford UK)
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buenos Aires
- Buffalo NY
- Burlington USA)
- Burlington VT
- C. Briani
- C. Bunschoten
- C. C. Chao
- C. Casasnovas
- C. Dornonville de la Cour
- C. Fokke
- C. G. Faber
- C. J. Gijsbers
- C. J. McDermott
- C. L. Sommer
- C. MĂĄrquez Infante
- C. Nascimbene
- Calgary Canada)
- Cambridge UK)
- Canada)
- Center
- Charlottesville USA)
- Chavada G.
- Chiba Japan)
- Chicago USA)
- Cologne Germany)
- Columbus USA)
- Copenhagen Denmark)
- Cordoba Spain)
- Cornblath D. R.
- Delft
- Department of Medicine
- Dhaka Bangladesh)
- DO (Lehigh Valley Health Network
- Dordrecht
- DĂŒsseldorf Germany)
- E. A. Fulgenzi
- E. Dardiotis
- E. Martinez Hernandez
- E. Nobile Orazio
- et al. J Neurol Neurosurg Psychiatry 2019
- F. A. Barroso
- F. Eftimov
- F. H. Vermeij
- Faculty of Medicine
- Fayetteville USA)
- FLENI
- FRCP (Ipswich Hospital
- FRCP (The Walton Centre
- G. A. Marfia
- G. Antonini
- G. Cavaletti
- G. Galassi
- G. Gutiérrez-Gutiérrez
- G. M. Sachs
- G. MorĂs de la Tassa
- G. W. van Dijk
- Genetics and Maternal and Infantile Sciences (DINOGMI)
- Genova
- Genova Italy)
- Glasgow UK)
- Glasgow UK)
- Glostrup Denmark)
- Gorson K. C.
- H. D. Katzberg
- H. J. Willison
- H. Lehmann
- H. Manji
- Harbo T.
- Hartung H. -P.
- Helmond and Deurne
- Homburg Germany)
- Hoorn
- Hospital Clinic
- Hospital of Larissa
- Houston USA)
- Hughes R. A. C.
- Humanitas Clinicala and Research Institute Milan
- I. Illa
- I. JericĂł Pascual
- I. R. Bella
- I. Rojas-Marcos
- Ipswich UK)
- Irvine USA)
- Islam Z.
- Italy 2. IRCCS Policlinico San Martino
- Italy)
- Italy)
- J. BĂŒrmann
- J. D. Varrato
- J. Gilhuis
- J. K. L. Holt
- J. M. Gilchrist
- J. P. A. Samijn
- J. Pardo Fernandez (Hospital ClĂnico de Santiago
- J. Roodbol
- J. S. Cosgrove
- J. Verschuuren
- J. Y. Kwan
- Jacksonville USA)
- Jacobs B. C.
- K. Doppler
- K. G. Claeys
- K. Jellema
- K. Kaida
- K. Kimpinski
- K. Kuitwaard
- K. Sheikh
- Kansas City
- Kusunoki S.
- L. Benedetti
- L. H. Visser
- L. Kiers
- L. Landschoff Lassen
- L. Querol Gutierrez
- L. Santoro
- L. Zhou
- La Spezia
- Larissa Greece)
- Leeds UK)
- Leiden
- Leiden
- Leuven Belgium
- Leuven Belgium)
- Leuven Belgium)
- LHSC London-Ontario
- Lingsma H.
- Liverpool UK)
- London UK)
- London UK)
- Lunn M. P.
- M. Busby
- M. C. Dalakas
- M. E. Conti
- M. G. Mattiazzi
- M. Htut
- M. J. Sedano Tous
- M. M. Dimachkie
- M. Mandarakas
- M. Osei-Bonsu (James Cook University Hospital
- M. P. J. Garssen
- M. Pulley
- M. S. Monges
- M. V. Vytopil
- Maastricht
- Malaya)
- Marseille France)
- Marseille France)
- MBChB
- MD
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- MD (Buffalo General Medical Center
- MD (Canisius Wilhelmina Hospital
- MD (CHU Timone
- MD (Columbia University
- MD (Dokkyo Medical University
- MD (Franciscus Gasthuis
- MD (Gelre Hospital
- MD (Glostrup Hospital
- MD (Heinrich Heine University
- MD (Hopital de Hautepierre
- MD (Hospital Cesar Milstein Buenos Aires
- MD (Hospital de PediatrĂa J. P. Garrahan
- MD (Hospital Militar Central
- MD (Hospital Universitario Central de Asturias
- MD (Hospital Universitario Infanta Sofia
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- MD (Instituto de Investigaciones NeurolĂłgicas RaĂșl Carrea
- MD (Leeds General Infirmary
- MD (Leeds General Infirmary
- MD (Mental Health and Sensory Organs (NESMOS)
- MD (Montefiore Medical
- MD (National Hospital Copenhagen
- MD (Neurological Clinic
- MD (Neurology Unit
- MD (Northwestern University Feinberg
- MD (Pinderfields Hospital
- MD (Royal Hallamshire Hospital
- MD (Scientific Institute San Raffaele
- MD (Soulthern Illinois University School of Medicine
- MD (St. Georgeâs Hospital
- MD (St. Josephâs Regional Medical Center
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- MD (University Hospital
- MD (University Hospital Clinicas
- MD (University Hospital of Modena
- MD (University Hospital/University of Texas Health Science Center
- MD (University Milano-Bicocca
- MD (University of Arkansas
- MD (University of Calgary
- MD (University of California
- MD (University of Florida
- MD (University of Glasgow
- MD (University of Kansas Medical Center
- MD (University of Maryland School of Medicine
- MD (University of Mass Medical School
- MD (University of Melbourne
- MD (University of Padova
- MD (University of Rhode Island
- MD (University of Thessaly
- MD (University of Toronto
- MD (University of Utah School of Medicine
- MD (University of Vermont
- MD (University of Vermont Medical Center
- MD (University of Virginia
- MD (UniversitĂ€tsklinikum WĂŒrzburg
- MD (UniversitĂ€tsklinikum WĂŒrzburg
- MD (Vlietland Hospital
- MD (Westfriesgasthuis
- MD (Wexner Medical Center at The Ohio State University
- MD (Yale University School of Medicine
- Memphis USA)
- Middlesbrough UK)
- Milan Italy)
- Milan Italy)
- Miller J.
- Modena Italy)
- Monza Italy)
- N. A. Goyal
- N. J. Silvestri
- N. Kokubun
- N. Kolb
- N. Shahrizaila
- Napels Italy)
- New Brunswick
- New Haven
- New York
- New York
- New York City
- NIHR Clinical
- Nijmegen
- P. Van Damme
- P. Wirtz
- Padova Italy)
- Pamplona Spain)
- Parkville Australia)
- Paterson USA)
- Pereon Y.
- PhD
- PhD (1. Department of Neurosciences
- PhD (1. University Hospitals Leuven
- PhD (Albert Schweitzer Hospital
- PhD (Amsterdam University Medical Centre
- PhD (Amsterdam University Medical Centre
- PhD (Bellvitge University Hospital â IDIBELL Neurometabolic Diseases Group. CIBERER
- PhD (Chiba University
- PhD (CHU Timone
- PhD (Complejo Hospitalario de Navarra
- PhD (Concord Repatriation General Hospital
- PhD (Elisabeth-TweeSteden Hospital
- PhD (Elkerliek Hospital
- PhD (Erasmus University Medical Centre
- PhD (Haaglanden Medisch Centrum
- PhD (HagaZiekenhuis
- PhD (Hospital de la Santa Creu i Sant Pau
- PhD (Hospital de la Santa Creu i Sant Pau
- PhD (Icahn School of Medicine at Mount Sinai
- PhD (International Centre for Diarrhoeal Disease Research
- PhD (Jeroen Bosch Hospital
- PhD (Kingâs College Hospital
- PhD (Leiden University Medical Centre
- PhD (Leiden University Medical Centre
- PhD (Luigi Sacco Hospital
- PhD (Maasstad Hospital
- PhD (Maastricht University Medical Centre
- PhD (Milan University
- PhD (National Defense Medical College
- PhD (National Institute of Neurosciences and Hospital
- PhD (National Taiwan University Hospital
- PhD (National Taiwan University Hospital
- PhD (Ospedale Santâ Andrea La Spezia
- PhD (Queen Elizabeth Hospital
- PhD (Reinier de Graaf Gasthuis
- PhD (Rutgers
- PhD (The University of Texas Health Science Center at Houston
- PhD (Tufts University School of Medicine Lahey Hospital W. Waheed
- PhD (University Federico II
- PhD (University Hospital Leuven
- PhD (University Hospital of Cologne
- PhD (University of Glasgow
- PhD (University of Oxford R. C. Roberts
- PhD (University of Pittsburgh Medical Center
- PhD candidate (Erasmus University Medical Centre
- PhD candidate (Erasmus University Medical Centre
- PhD candidate (Erasmus University Medical Centre
- PhD candidate (Erasmus University Medical Centre
- Philadelphia USA
- Phoenix Arizona
- Pittsburgh USA).
- Policlinico Tor Vergata
- Providence USA)
- Q. D. Mohammad
- R. Bhavaraju-Sanka
- R. D. M. Hadden
- R. Fazio
- R. J. Nowak
- R. Reisin (Hospital Britanico
- R. van Koningsveld
- Rehabilitation Ophthalmology
- Robert Wood Johnson University Hospital
- Rome Italy)
- Rome Italy)
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Rotterdam
- Royal Melbourne Hospital
- S. A. Rudnicki
- S. A. Zivkovich
- S. Attarian
- S. Butterworth
- S. Chen
- S. Consortia. Protected by copyright. on October 7
- S. E. Leonhard
- S. Karafiath
- S. Kuwabara
- S. Rinaldi
- S. S. Ladha
- S. T. Hsieh
- S. W. Reddel
- Saitama Japan)
- Salt Lake City
- San Antonio Texas
- San Sebastian
- Santander Cantabria
- Santiago de Compostela (A Coruña)
- SantâAndrea Hospital
- Sapienza University
- Schiedam
- Seville Spain)
- Sheffield UK)
- Sindrup So. H.
- Spain)
- Spain)
- Spain)
- Springfield USA)
- Strasbourgh France)
- Sydney Australia)
- T. E. Bertorini
- T. E. Feasby
- T. Fujioka
- T. H. Brannagan
- T. van der Ree
- Taipei Taiwan)
- Taipei Taiwan)
- The Hague
- The Hague
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- the Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- the Netherlands)
- the Netherlands)
- The Netherlands)
- the Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- The Netherlands)
- Tilburg and Waalwijk
- Tochigi Japan)
- Tokyo Japan)
- Toronto Canada)
- Universitat AutĂČnoma de Barcelona
- Universitat AutĂČnoma de Barcelona
- University of Genova
- University of Malaya
- UniversitÀtsklinikum des Saarlandes
- UniversitÀtsklinikum Köln
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA)
- USA). Other collaborators were:U. A. Badrising
- V. Granit
- V. Lawson
- Van Den Berg B.
- Van Den Bergh P.
- Van Doorn P. A. J. M. Addington
- Venema E.
- Verboon C.
- Wakefield UK)
- Worcester USA)
- WĂŒrzburg Germany)
- WĂŒrzburg Germany)
- Y. A. Rajabally
- Zaltbommel and Drunen
- Zutphen and Apeldoorn
- âs Hertogenbosch
- Publication venue
- 'BMJ'
- Publication date
- 01/01/2020
- Field of study
Objective To compare disease course in patients with Guillain-Barré syndrome (GBS) with a poor prognosis who were treated with one or with two intravenous immunoglobulin (IVIg) courses. Methods From the International GBS Outcome Study, we selected patients whose modified Erasmus GBS Outcome Score at week 1 predicted a poor prognosis. We compared those treated with one IVIg course to those treated with two IVIg courses. The primary endpoint, the GBS disability scale at 4 weeks, was assessed with multivariable ordinal regression. Results Of 237 eligible patients, 199 patients received a single IVIg course. Twenty patients received an α early' second IVIg course (1-2 weeks after start of the first IVIg course) and 18 patients a α late' second IVIg course (2-4 weeks after start of IVIg). At baseline and 1 week, those receiving two IVIg courses were more disabled than those receiving one course. Compared with the one course group, the adjusted OR for a better GBS disability score at 4 weeks was 0.70 (95%CI 0.16 to 3.04) for the early group and 0.66 (95%CI 0.18 to 2.50) for the late group. The secondary endpoints were not in favour of a second IVIg course. Conclusions This observational study did not show better outcomes after a second IVIg course in GBS with poor prognosis. The study was limited by small numbers and baseline imbalances. Lack of improvement was likely an incentive to start a second IVIg course. A prospective randomised trial is needed to evaluate whether a second IVIg course improves outcome in GBS