Parameter Inference in the Pulmonary Circulation of Mice

This study focuses on parameter inference in a pulmonary blood cir- culation model for mice. It utilises a fluid dynamics network model that takes selected parameter values and aims to mimic features of the pulmonary haemody- namics under normal physiological and pathological conditions. This is of medical relevance as it allows monitoring of the progression of pulmonary hypertension. Constraint nonlinear optimization is successfully used to learn the parameter values

Effect of Rabbit Production Factors on Revenue of Rabbit Farmers in Berastagi District, Karo Regency

The aim of this research was to investigate the influence of rabbitproduction factors on rabbit farmers income in the District of Berastagi Regency ofKaro which include Litter Size, Sum of Wean, Sum of Deaths, Feed Cost and Sum ofLabor; and knowing rabbit business in District of Berastagi Regency of Karo isdeserves to be forwarded. The research method used census method done twice for twomonths to take as many as 48 respondent farmers. Factor analysis was obtained byregression analysis while business feasibility obtained by Revenue Cost Ratio (RatioR/C), Benefit Cost Ratio (Rasio B/C) and Break Event Point (BEP) analysis. Theresults showed that the factor affect rabbit farmers income were Sum of Deaths andSum of Labor. Financial analysis of rabbit farmers were R/C=5,61, B/C=4,24, PriceBEP=Rp 9.875 dan Production BEP=22 pieces. It conclude that the factor affect rabbitfarmers income were Sum of Death and Sum of Labor. Rabbit business is profitableand feasible to conduct

Konsep Kampung Pendidikan dan Pelatihan Kerja

Pembangunan perdesaan adalah bagian integral dari pembangunan Indonesia, hakekat pembangunan adalah pembangunan manusia dan sumber daya manusia di perdesaan masih sangat rendah sehingga, arah pembangunan desa sebaiknya mengutamakan manusia dan penciptaan lapangan kerja. Penelitian ini bertujuan (1) mengetahui fasilitas yang dibutuhkan oleh masyarakat perdesaan sebagai prasarana belajar, (2) menemukan rumusan kawasan binaan kampung kerja sebagai kawasan aglomerasii pendidikan sebagai upaya peningkatan kualitas sumber daya masyarakat desa. Penelitian ini diselenggarakan di Kabupaten Muna dan metode penelitian ini berlandaskan pada paradigma post-positivisme yakni metode studi kasus pendekatan kualitatif dimana aspek – aspek yang dianalisis adalah angkatan kerja, sektor ekonomi, kebutuhan bangunan, infrastruktur, dan zonasi keruangan. Penelitian ini menemukan dua temuan (1) kebutuhan akan fasilitas yang dibutuhkan untuk peningkatan kualitas angkatan kerja, (2) rumusan model kawasan binaan kampung pendidikan dan pelatihan kerja sebagai kawasan aglomerasi peningkatan sumber daya manusia perdesaan.Rural development is an integral part of Indonesia\u27s development, the essence of development is human development and human resources in rural areas are still very low so that the direction of rural development should prioritize humans and job creation. The objetives of this research are (1) find out the facilities needed by rural communities as learning infrastructure, (2) find the formulation of the working area of the working village as an educational agglomeration area as an effort to improve the quality of rural community resources. This research was conducted in Muna Regency and this research method was based on the post-positivism paradigm, a case study method of qualitative approach where the aspects analyzed were labor force, economic sector, building needs, infrastructure, and spatial zoning. This study found two findings (1) the need for facilities needed to improve the quality of the workforce, (2) the formulation of the model of the village built area of education and job training as an agglomeration area to increase rural human resources

Dialektika Arsitektur dan Perubahan Perilaku Masyarakat Pasca Urbanisasi

Paradigma ber-arsitektur erat kaitannya dengan perilaku masyarakat sehingga arsitektur dapat digunakan untuk membentuk perilaku manusia melalui rekayasa lingkungan maupun bangunan.. Masuknya arsitektur moderen di Indonesia berakibat pada Perubahan perilaku masyarakat tradisional khususnya di wilayah urban olehnya, penelitian ini bertujuan (1) mendokumentasikan faktor - faktor yang menyebabkan Peruban perilaku masyarakat pra urban (masyarakat tradisional) pasca urbanisasi di Kota Kendari dalam perspektif kearsitektural, lingkungan dan paradigma filsafat, (2) merumuskan langkah dan tindakan kearsitektural dalam upaya merestorasi nilai - nilai kebudayaan terhadap masyarakat urban. Penelitian ini diselenggarakan di kota Kendari dan berlandaskan pada paradigma post-positivisme yakni metode fenomenologi pendekatan kualitatif dimana aspek – aspek yang dianalisis pedagogi, lingkungan dan perilaku, serta budaya masyarakat kota Kendari dan Sulawesi Tenggara pada umumya sebagai landasan determinisme arsitektur. Penelitian ini menemukan dua temuan yakni (1) uraian deskriptif paradigma filsafat terhadap pendidikan dan konsepsi arsitek dan user mengenai arsitektur yang mengakibatkan Perubahan perilaku masyarakat urban, (2) rumusan model kawasan kantong pedestrian dengan fasilitas terpadu berbasis lingkungan dan kearifan lokal sebagai determinisme arsitektur dalam merestorasi nilai – nilai budaya pada masyarakat urban

Center-of-mass motion and cross-channel coupling in time-dependent Hartree-Fock theory

We provide a discussion of issues related to the center-of-mass motion and cross-channel coupling in applications of the time-dependent Hartree-Fock (TDHF) theory to heavy-ion collisions. We find that the entrance channel dynamics of a heavy-ion collision as described by TDHF does not seem to be significantly influenced by these effects, whereas the long-time evolution may be less reliable.Comment: 4 pages, 4 figure

MCMC with Delayed Acceptance using a Surrogate Model with an Application to Cardiovascular Fluid Dynamics

Parameter estimation and uncertainty quantification in physiological modelling is a vital step towards personalised medicine. Current state-of-the-art in this research area performs parameter optimisation, with very limited uncertainty quantification. This paper demonstrates the advantage of novel sampling methods, applied on a complex biological PDE system of the pulmonary circulation. The aim is to find an efficient and accurate method for the inference and uncertainty quantification of unknown parameters, relevant for disease diagnosis (pulmonary hypertension) from limited and noisy blood pressure data. The data likelihood is expensive to evaluate as it requires solving numerically a system of PDEs. Therefore, having a model that best trades off accuracy and computational efficiency is of uppermost importance. In this study, we employ fast Bayesian methods, namely MCMC algorithms coupled with emulation using Gaussian Processes, to achieve a computational speed-up. We compare the Delayed Rejection Adaptive Metropolis algorithm in a History Matching framework to the delayed acceptance Adaptive Metropolis algorithm. The first algorithm draws samples from the approximate posterior distribution, while the latter is guaranteed to generate samples from the exact posterior distribution asymptotically. In this paper we propose and derive the n-steps ahead delayed acceptance Metropolis-Hastings algorithm, which is a generalisation of the classical 1-step ahead delayed acceptance Metropolis-Hastings. We show the superiority of the n-steps ahead algorithm over the 1-step ahead method

Development of A Fingerprint Biometric Authentication System For Secure Electronic Voting Machines

            Democratic government in the world today rely on electronic voting as the foremost means of providing credible, transparent and fair elections for the electorate. There is a need for developed electronic voting systems to be security enhanced to ensure the authenticity of the developed system. Traditional paper balloting systems suffer from vote tampering, multiple voting and illegal voting by unregistered voters. They are also, susceptible to under aged voting due to the difficulty in authenticating the identity of prospective voters. Manual collation and publication of vote results also leads to slow response times and inaccuracies in published results. This research paper proposes a system to combat the current challenges through the development of a fingerprint biometric authentication system for secure electronic voting machines. It uses a fingerprint biometric sensor, integrated via Python to verify users of the system. The inclusion of biometrics improves the security features of the system. The secure voting system is built using PHP and easy to use Graphical User Interface was designed using HTML and CSS. Users are required to interact with the machine via a 7” touchscreen interface. From the results, it shows that the developed machine has a minimum response time of 0.6 seconds for specific operation, an FAR of 2%, FRR of 10% and overall system accuracy of 94%. The developed machine is able to combat the challenges of authentication of users, thereby guaranteeing the transparency, credibility, integrity and vote authenticity of the elections

The effect of aqueous extracts of Hibiscus sabdariffa (Sorrel) calyces on heamatological profile and organ pathological changes in Trypanasoma congolense – infected rat

The effects of aqueous extract of Hibiscus sabdariffa calyces on haematology and pathological changes in some selected organs during experimental Trypanosoma congolense infection of rats were investigated. Three groups of rats were intraperitoneally infected with T. congolense (Karu stock). One group was administered with the aqueous extract and another given a solution of vitamin C in drinking water; the remaining infected group was left untreated. Data from these groups were compared with those of two groups of healthy rats, one of which was similarly treated with the aqueous extract. The experiment was terminated three weeks, post-infection (pi). The uninfected and infected rats administered the extract consumed the equivalent of 9.94 mg – and 9.61 mg ascorbic acid / 100g / day during the experiment. Consumption of the extract significantly (