Multianalyte Sensing Of Addictive Over-the-counter (otc) Drugs

A supramolecular sensor array composed of two fluorescent cucurbit[n]uril-type receptors (probe 1 and probe 2) displaying complementary selectivities was tested for its ability to detect and quantify drug-related amines. The fluorimetric titration of the individual probes showed highly variable and cross-reactive analyte-dependent changes in fluorescence. An excellent ability to recognize a variety of analytes was demonstrated in qualitative as well as quantitative assays. Importantly, a successful quantitative analysis of several analytes of interest was achieved in mixtures and in human urine. The throughput and sensitivity surpass those of the current state-of-the-art methods that usually require analyte solid-phase extraction (SPE). These results open up the opportunity for new applications of cucurbit[n]uril-type receptors in sensing and pave the way for the development of simple high-throughput assays for various drugs in the near future

Bibliotherapy Storybook Construction: A Creative Interpretation Based on Children\u27s Goals, Wants, and Hindrances

The difficulty to continue education in the Philippines, especially in the case of children, more often than not results from lack of motivation amid poverty. This problem brought the reason for this study — to create a way to spark motivation to continue education through a bibliotherapy storybook. Data were collected among twelve respondents, ages 6-12, through questionnaires describing their goals, wants, and hindrances, using coloring materials. Through thematic analysis, results show that most of the respondents were inclined to choose social service occupations that will help provide housing for their family. However, a considerable number of them expressed fear of not being able to finish school. The results were utilized to undertake a creative interpretation, completing the production process from narrative components to digital artwork. The created bibliotherapy storybook, Ang Paligsahan ng Hari sa Kastilyo, was then validated by eight experts and received an exemplary rating as a qualified material for bibliotherapy. This study successfully provided a method on how to construct a bibliotherapy storybook from one\u27s perspective. Hence, further studies may be conducted to test the created bibliotherapy for its motivational effects from the user\u27s perspective

A study on the relationship of stock market index price, foreign exchange rate, and interest rate swap (IRS) rate to sovereign credit default swap spreads (CDS) of Vietnam, Indonesia and Philippines (VIP) for the years 2007-2011

This study examined the relationship between the independent variables, namely, the stock market index price, foreign exchange rate, and interest rate swap (IRS) rates, with the dependent variable, the sovereign CDS spreads, of countries Vietnam, Indonesia, and Philippines for the years 2007-2011 using the Pearson\u27s correlation coefficient model and the Johansen\u27s cointegration rank test. The least-squares dummy variable (LSDV) model was used to determine the significance of the independent variables to the movements of the CDS spreads for each country in the five-year time period in assessing the default risk of a country. Based on the results of the Pearson\u27s correlation, only the IRS rate of the Philippines did not follow the a-priori expectation however, since correlation only measures the short run relationship, it does not determine the long run relationship so, cointegration was used. As for the Johansen\u27s cointegration rank test, only the Philippine stock market price, USD/PHP foreign exchange rate and Ho Chi Minh stock market index price were cointegrated with their respective CDS spreads. All of the explanatory variables contribute a significant effect to the movement of the CDS spreads as shown by the LSDV model however, the time dummies were found to be insignificant