64 research outputs found
Neuroretinitis following bull ant sting
Cat scratch disease causes the majority of cases of neuroretinitis. Neuroretinitis is characterised by clinical features of papillitis, macular oedema and macular star. We report a case study of infection with Bartonella henselae most likely transmitted by a bull ant sting. The patient presented with blurred vision and reduced visual acuity after being stung by an ant in her garden some 7 days earlier. Further testing revealed positive serology to B henselae and the patient improved with appropriate treatment
Recurrent atypical fibroxanthoma of the limbus
Author version made available in accordance with the publisher's policy.We report an unusual presentation of recurrent atypical fibroxanthoma of the limbus. Clinical and histological appearance, as well as management are discussed and the current literature is reviewed
Fachinformationsdienst (FID) Soziologie: Evaluationsbericht, Bedarfserhebung 2021
Der Fachinformationsdienst (FID) Soziologie bietet der wissenschaftlichen Fachcommunity mit dem Portal SocioHub (sociohub-fid.de) einen zentralen Einstieg in die Literatur- und Informationssuche sowie eine Plattform für die digitale Forschungskommunikation. Im Januar/Februar 2021 hat der FID Soziologie eine Online-Befragung durchgeführt, um Erkenntnisse über Nutzungsverhalten, Zufriedenheit und Bedarfe der Fachcommunity in den Themenbereichen Technische Infrastruktur & Portal, Literaturrecherche & Content, Kommunikation & Kollaboration, Forschungsdaten, Open-Access-Publizieren und Öffentlichkeitsarbeit zu ermitteln. Die Ergebnisse zeigen ein wachsendes Interesse in den Bereichen Open-Access-Publizieren und digitale Informationsangebote. Deutlich wurde darüber hinaus, dass die Bekanntheit des Dienstes in der Fachcommunity erhöht und die konkreten Angebote noch gezielter vermittelt werden müssen
Schülerexperimente im inklusiven Physikunterricht
Auch 11 Jahre nach der Ratifizierung der UN-Behindertenrechtskonvention mangelt es an Unterrichtskonzepten insbesondere für den inklusiven Physikunterricht. Experimente werden als das wichtigste Medium des Physikunterrichts angesehen. Das Projekt „Fortbildung zum inklusiven Experimentieren im Physikunterricht” (FINEX) möchte beides verbinden und hat ein theoriebasiertes Unterrichtskonzept für inklusive Schülerexperimente entwickelt. Herzstück dieses Konzeptes ist eine Stationenarbeit, welche fünf handlungsorientierte Zugänge zu einem physikalischen Kontext bietet. An den Stationen sollen Schüler*innen selbstgesteuert multimediale Experimente durchführen. Anhand eines Beispiels aus der geometrischen Optik wird dieses Unterrichtskonzept illustriert. Das begleitende Arbeitsmaterial dient als Grundlage für eine für 2021 geplante Lehrkräftefortbildung
Schülerexperimente im inklusiven Physikunterricht
Auch 11 Jahre nach der Ratifizierung der UN-Behindertenrechtskonvention mangelt es an Unterrichtskonzepten insbesondere für den inklusiven Physikunterricht. Experimente werden als das wichtigste Medium des Physikunterrichts angesehen. Das Projekt „Fortbildung zum inklusiven Experimentieren im Physikunterricht” (FINEX) möchte beides verbinden und hat ein theoriebasiertes Unterrichtskonzept für inklusive Schülerexperimente entwickelt. Herzstück dieses Konzeptes ist eine Stationenarbeit, welche fünf handlungsorientierte Zugänge zu einem physikalischen Kontext bietet. An den Stationen sollen Schüler*innen selbstgesteuert multimediale Experimente durchführen. Anhand eines Beispiels aus der geometrischen Optik wird dieses Unterrichtskonzept illustriert. Das begleitende Arbeitsmaterial dient als Grundlage für eine für 2021 geplante Lehrkräftefortbildung
Treatment and Outcome of Osteoporotic Thoracolumbar Vertebral Fractures With Anterior or Posterior Tension Band Failure (OF 5): Short-Term Results From the Prospective EOFTT Multicenter Study.
STUDY DESIGN
Subgroup analysis of a multicenter prospective cohort study.
OBJECTIVE
To analyse surgical strategies applied to osteoporotic thoracolumbar osteoporotic fracture (OF) 5 injuries with anterior or posterior tension band failure and to assess related complications and clinical outcome.
METHODS
A multicenter prospective cohort study (EOFTT) was conducted at 17 spine centers including 518 consecutive patients who were treated for an osteoporotic vertebral fracture (OVF). For the present study, only patients with OF 5 fractures were analysed. Outcome parameters were complications, Visual Analogue Scale (VAS), Oswestry Disability Questionnaire (ODI), Timed Up & Go test (TUG), EQ-5D 5L, and Barthel Index.
RESULTS
In total, 19 patients (78 ± 7 years, 13 female) were analysed. Operative treatment consisted of long-segment posterior instrumentation in 9 cases and short-segment posterior instrumentation in 10 cases. Pedicle screws were augmented in 68 %, augmentation of the fractured vertebra was performed in 42%, and additional anterior reconstruction was done in 21 %. Two patients (11 %) received short-segment posterior instrumentation without either anterior reconstruction or cement-augmentation of the fractured vertebra. No surgical or major complications occurred, but general postoperative complications were observed in 45%. At a follow-up of mean 20 ± 10 weeks (range, 12 to 48 weeks), patients showed significant improvements in all functional outcome parameters.
CONCLUSIONS
In this analysis of patients with type OF 5 fractures, surgical stabilization was the treatment of choice and lead to significant short-term improvement in terms of functional outcome and quality of life despite a high general complication rate
Georg Schmorl prize of the German spine society (DWG) 2022: current treatment for inpatients with osteoporotic thoracolumbar fractures-results of the EOFTT study
AIM
Osteoporotic thoracolumbar fractures are of increasing importance. To identify the optimal treatment strategy this multicentre prospective cohort study was performed.
PURPOSE
Patients suffering from osteoporotic thoracolumbar fractures were included. Excluded were tumour diseases, infections and limb fractures. Age, sex, trauma mechanism, OF classification, OF-score, treatment strategy, pain condition and mobilization were analysed.
METHODS
A total of 518 patients' aged 75 ± 10 (41-97) years were included in 17 centre. A total of 174 patients were treated conservatively, and 344 were treated surgically, of whom 310 (90%) received minimally invasive treatment. An increase in the OF classification was associated with an increase in both the likelihood of surgery and the surgical invasiveness.
RESULTS
Five (3%) complications occurred during conservative treatment, and 46 (13%) occurred in the surgically treated patients. 4 surgical site infections and 2 mechanical failures requested revision surgery. At discharge pain improved significantly from a visual analogue scale score of 7.7 (surgical) and 6.0 (conservative) to a score of 4 in both groups (p < 0.001). Over the course of treatment, mobility improved significantly (p = 0.001), with a significantly stronger (p = 0.007) improvement in the surgically treated patients.
CONCLUSION
Fracture severity according to the OF classification is significantly correlated with higher surgery rates and higher invasiveness of surgery. The most commonly used surgical strategy was minimally invasive short-segmental hybrid stabilization followed by kyphoplasty/vertebroplasty. Despite the worse clinical conditions of the surgically treated patients both conservative and surgical treatment led to an improved pain situation and mobility during the inpatient stay to nearly the same level for both treatments
Treatment and Outcome of Osteoporotic Thoracolumbar Vertebral Body Fractures With Deformation of Both Endplates With or Without Posterior Wall Involvement (OF 4): Short-Term Results from the Prospective EOFTT Multicenter Study.
STUDY DESIGN: Multicenter prospective cohort study.
OBJECTIVE: To analyse therapeutical strategies applied to osteoporotic thoracolumbar OF 4 injuries, to assess related complications and clinical outcome.
METHODS: A multicenter prospective cohort study (EOFTT) including 518 consecutive patients who were treated for an Osteoporotic vertebral compression fracture (OVCF). For the present study, only patients with OF 4 fractures were analysed. Outcome parameters were complications, Visual Analogue Scale, Oswestry Disability Questionnaire, Timed Up & Go test, EQ-5D 5L, and Barthel Index after a minimum follow-up of 6 weeks.
RESULTS: A total of 152 (29%) patients presented with OF 4 fractures with a mean age of 76 years (range 41-97). The most common treatment was short-segment posterior stabilization (51%; hybrid stabilization in 36%). Mean follow up was 208 days (±131 days), mean ODI was 30 ± 21. Dorsoventral stabilized patients were younger compared to the other groups (P .602, Barthel: P > .252, EQ-5D 5L index value: P > .610, VAS-EQ-5D 5L: P = 1.000). The inpatient complication rate was 8% after conservative and 16% after surgical treatment. During follow-up period 14% of conservatively treated patients and 3% of surgical treated patients experienced neurological deficits.
CONCLUSIONS: Conservative therapy of OF 4 injuries seems to be viable option in patients with only moderate symptoms. Hybrid stabilization was the dominant treatment strategy leading to promising clinical short-term results. Stand-alone cement augmentation seems to be a valid alternative in selected cases
Clinical Evaluation of the Osteoporotic Fracture Treatment Score (OF-Score): Results of the Evaluation of the Osteoporotic Fracture Classification, Treatment Score and Therapy Recommendations (EOFTT) Study.
STUDY DESIGN
Multicenter prospective cohort study.
OBJECTIVE
The study aims to validate the recently developed OF score for treatment decisions in patients with osteoporotic vertebral compression fractures (OVCF).
METHODS
This is a prospective multicenter cohort study (EOFTT) in 17 spine centers. All consecutive patients with OVCF were included. The decision for conservative or surgical therapy was made by the treating physician independent of the OF score recommendation. Final decisions were compared to the recommendations given by the OF score. Outcome parameters were complications, Visual Analogue Scale, Oswestry Disability Questionnaire, Timed Up & Go test, EQ-5D 5 L, and Barthel Index.
RESULTS
In total, 518 patients (75.3% female, age 75 ± 10) years were included. 344 (66%) patients received surgical treatment. 71% of patients were treated following the score recommendations. For an OF score cut-off value of 6.5, the sensitivity and specificity to predict actual treatment were 60% and 68% (AUC .684, P < .001). During hospitalization overall 76 (14.7%) complications occurred. The mean follow-up rate and time were 92% and 5 ± 3.5 months, respectively. While all patients in the study cohort improved in clinical outcome parameters, the effect size was significantly less in the patients not treated in line with the OF score's recommendation. Eight (3%) patients needed revision surgery.
CONCLUSIONS
Patients treated according to the OF score's recommendations showed favorable short-term clinical results. Noncompliance with the score resulted in more pain and impaired functional outcome and quality of life. The OF score is a reliable and save tool to aid treatment decision in OVCF
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