Antitumor drugs reval that eukaryotic elongation factors EeflBγ and eEF1Bd are phosphorylated durging mitosis

Comunicaciones a congreso

The antitumor drug vinblastine induces the phosphorylation of annexin A2

Comunicaciones a congreso

Phosphorylation of p54NRB during mitosis

Comunicaciones a congreso

Team dynamics in emergency surgery teams: results from a first international survey

Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma\u2019s causes or the patient\u2019s personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ensuring the best performance and outcomes. Methods: An online survey was conducted among the World Society of Emergency Surgery members in early 2021. 402 fully filled questionnaires on the topics of knowledge translation dynamics and tools, non-technical skills, and difficulties in teamwork were collected. Data were analyzed using the software R, and reported following the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). Results: Findings highlight how several surgeons are still unsure about the meaning and potential of knowledge translation and its mechanisms. Tools like training, clinical guidelines, and non-technical skills are recognized and used in clinical practice. Others, like patients\u2019 and stakeholders\u2019 engagement, are hardly implemented, despite their increasing importance in the modern healthcare scenario. Several difficulties in working as a team are described, including the lack of time, communication, training, trust, and ego. Discussion: Scientific societies should take the lead in offering training and support about the abovementioned topics. Dedicated educational initiatives, practical cases and experiences, workshops and symposia may allow mitigating the difficulties highlighted by the survey\u2019s participants, boosting the performance of emergency teams. Additional investigation of the survey results and its characteristics may lead to more further specific suggestions and potential solutions

The trade-off between genetic gain and conservation in a participatory improvement programme: the case of peach palm (Bactris gasipaes Kunth)

Finding an equilibrium between genetic resources conservation and genetic improvement can be difficult. The problem is explored in this paper, partly through a case study of a participatory improvement programme of peach palm (Bactris gasipaes Kunth, Palmae), implemented in the Peruvian Amazon by the World Agroforestry Centre (ICRAF) and the Peruvian National Institute for Agricultural Research and Extension (INIEA). Peach palm, which was originally domesticated by Amerindians, produces a range of useful substance and marketable products, but today the fruit and heart-of-palm are the principal products. The characteristics of the clients (subsistence smallholders and agro-industrial plantation companies) for these crops and those of the ICRAF-INIEA project are described, and the impact on genetic diversity of future management options is explored. This is followed by a wider discussion of the relationships between genetic gain and maintenance of genetic diversity for improvement, and their implications.\ud \ud The ICRAF-INIEA programme was designed to emphasize genetic conservation and timely germplasm delivery rather than genetic gain. The analysis presented here suggests that, with careful management, genetic diversity can be effectively conserved through 20 generations of improvement. Nevertheless, there is a fundamental conflict between genetic gain and genetic conservation. Consequently, no improvement programme can conserve all of the genetic diversity of a landrace or species and genetic resource management strategies must be developed to resolve these conflicts through explicit and informed decisions. Some such strategies, corresponding to different levels of emphasis on gain versus diversity, are presented

Genomics of tolerance to abiotic stress in the Triticeae

Genomics platforms offer unprecedented opportunities to identify, select and in some cases clone the genes and the quantitative trait loci (QTLs) that govern the tolerance of Triticeae to abiotic stresses and, consequently, grain yield. Transcriptome profiling and the other \u201comics\u201d platforms provide further information to unravel gene functions and validate the role of candidate genes. This review provides a synopsis of the main results on the studies that have investigated the genomics of Triticeae crops under conditions of abiotic constraints. With their rich biodiversity and high functional plasticity in response to environmental stresses, Triticeae crops provide an ideal ground for taking full advantage of the opportunities offered by genomics approaches. Ultimately, the practical impact of the knowledge and materials generated through genomics-based approaches will depend on their integration and exploitation within the extant breeding programs