32 research outputs found
Normal Immunoglobulin: Intravenous or Intramuscular? Appropriate and Non-Appropriate Uses
No full text
Influence of the Cryoprotective Agents Glycerol and Hydroxyethyl Starch on Red Blood Cell ATP and 2,3-Diphosphoglyceric Acid Levels
No full textDefining the Specificity of Anti-A/B IgM/G Antibodies with Different Antigens and Lectins
No full textAntiidiotypic Immunosuppression and Its Treatment with Human Immunoglobulin Preparations
No full textEvaluation of Complement Activation on Cardiopulmonary Bypass and in Retransfused Oxygenator and Shed Mediastinal Blood
No full textSeveral methods of blood salvage are used in cardiac surgery. Our aim was to study, on the basis of complement activation, the quality of autologous blood products reinfused to the patient. Eleven patients with elective myocardial revascularisation were studied for: operative and cardiopulmonary bypass (CPB) data, hematology, blood chemistry and complement activation (C3a [des Arg] and terminal complement complex [TCC] or C5b-9 complex). Centrifugated oxygenator blood (COB) and shed mediastinal blood (SMB) samples were examined before reinfusion into the patient and the effect of this retransfusion on the systemic values.
The activation pattern for C3a [des Arg] and TCC was similar. Thus only evaluation of C3a [des Arg] is reported.
Anesthesia increased C3a [des Arg] two fold over baseline (85 +/- 64 vs. 161 +/-103 ng/ml [standardised]; ns)
