Self-referencable frequency comb from a 170-fs, 1.5-μm solid-state laser oscillator

We report measurement of the first carrier-envelope offset (CEO) frequency signal from a spectrally broadened ultrafast solid-state laser oscillator operating in the 1.5μm spectral region. The f-to-2f CEO frequency beat signal is 49 dB above the noise floor (100-kHz resolution bandwidth) and the free-running linewidth of 3.6 kHz is significantly better than typically obtained by ultrafast fiber laser systems. We used a SESAM mode-locked Er:Yb:glass laser generating 170-fs pulses at a 75MHz pulse repetition rate with 110-mW average power. It is pumped by one standard telecom-grade 980-nm diode consuming less than 1.5W of electrical power. Without any further pulse compression and amplification, a coherent octave-spanning frequency comb is generated in a polarization-maintaining highly-nonlinear fiber (PM-HNLF). The fiber length was optimized to yield a strong CEO frequency beat signal between the outer Raman soliton and the spectral peak of the dispersive wave within the supercontinuum. The polarization-maintaining property of the supercontinuum fiber was crucial; comparable octave-spanning supercontinua from two non-PM fibers showed higher intensity noise and poor coherence. Astable CEO-beat was observed even with pulse durations above 200fs. Achieving a strong CEO frequency signal from relatively long pulses with moderate power levels substantially relaxes the demands on the driving laser, which is particularly important for novel gigahertz diode-pumped solid-state and semiconductor laser

Evolution of oxygen utilization in multicellular organisms and implications for cell signalling in tissue engineering

Oxygen is one of the critically defining elements resulting in the existence of eukaryotic life on this planet. The rise and fall of this element can be tracked through time and corresponds with the evolution of diverse life forms, development of efficient energy production (oxidative phosphorylation) in single cell organisms, the evolution of multicellular organisms and the regulation of complex cell phenotypes. By understanding these events, we can plot the effect of oxygen on evolution and its direct influence on different forms of life today, from the whole organism to specific cells within multicellular organisms. In the emerging field of tissue engineering, understanding the role of different levels of oxygen for normal cell function as well as control of complex signalling cascades is paramount to effectively build 3D tissues in vitro and their subsequent survival when implanted

The Length of an SLE - Monte Carlo Studies

The scaling limits of a variety of critical two-dimensional lattice models are equal to the Schramm-Loewner evolution (SLE) for a suitable value of the parameter kappa. These lattice models have a natural parametrization of their random curves given by the length of the curve. This parametrization (with suitable scaling) should provide a natural parametrization for the curves in the scaling limit. We conjecture that this parametrization is also given by a type of fractal variation along the curve, and present Monte Carlo simulations to support this conjecture. Then we show by simulations that if this fractal variation is used to parametrize the SLE, then the parametrized curves have the same distribution as the curves in the scaling limit of the lattice models with their natural parametrization.Comment: 18 pages, 10 figures. Version 2 replaced the use of "nu" for the "growth exponent" by 1/d_H, where d_H is the Hausdorff dimension. Various minor errors were also correcte

Hastings' additivity counterexample via Dvoretzky's theorem

The goal of this note is to show that Hastings' counterexample to the additivity of minimal output von Neumann entropy can be readily deduced from a sharp version of Dvoretzky's theorem on almost spherical sections of convex bodies.Comment: 12 pages; v.2: added references, Appendix A expanded to make the paper essentially self-containe

Power dependence of supercontinuum noise in uniform and tapered PCFs

An error was made in the calculation of the relative intensity noise (RIN) because of an incorrectly specified value of the photodetector DC transimpedance gain

Language assessment in Wada test: Comparison of methohexital and amobarbital

AbstractIntroductionMethohexital has replaced amobarbital during Wada testing at many centers. The objective of our study was to compare the use of methohexital and amobarbital during Wada testing regarding language and memory lateralization quotients as well as speech arrest times.MethodsA chart review of 582 consecutive patients undergoing 1041 Wada-procedures was performed (left=60, right=63, bilateral=459). Language lateralization was calculated based on duration of speech arrest using a laterality index, defined as (L−R)/(L+R). Memory lateralization was expressed as percentage of retained objects and laterality quotient.ResultsLanguage and memory lateralization revealed a similar distribution with amobarbital and methohexital. Speech arrest after left and right-sided injection was significantly longer in the amobarbital group as compared to the methohexital group. Language lateralization did not differ in the two groups. Percentage of retained memory items was higher in the methohexital group and there were fewer presented test items in the methohexital group.DiscussionLanguage and memory testing during the Wada test can successfully be performed with methohexital instead of amobarbital. The shorter half-life of methohexital allows repeated injections and shorter interhemispheric testing intervals, but also shortens the testing window

Variation between centres in access to renal transplantation in UK: longitudinal cohort study

Objective To assess whether equity exists in access to renal transplantation in the UK after adjustment for case mix in incident patients with end stage renal disease

Occupancy based household energy disaggregation using ultra wideband radar and electrical signature profiles

Human behaviour and occupancy accounts for a substantial proportion of variation in the energy efficiency pro le of domestic buildings. Yet while people often claim that they would like to reduce their energy bills, rhetoric frequently fails to match action due to the effort involved in understand- ing and changing deeply engrained energy consumption habits. Here, we present and, through dedicated experiments, test in-house developed soft-ware to remotely identify appliance energy usage within buildings, using energy equipment which could be placed at the electricity meter location. Furthermore, we monitor and compare the occupancy of the location under study through Ultra-Wideband (UWB) radar technology and compare the resulting data with those received from the power monitoring software, via time synchronization. These signals when mapped together can potentially provide both occupancy and speci c appliances power consumption, which could enable energy usage segregation on a yet impossible scale as well as usage attributable to occupancy behaviour. Such knowledge forms the basis for the implementation of automated energy saving actions based on a households unique energy profi le

Why dynamos are prone to reversals

In a recent paper (Phys. Rev. Lett. 94 (2005), 184506; physics/0411050) it was shown that a simple mean-field dynamo model with a spherically symmetric helical turbulence parameter alpha can exhibit a number of features which are typical for Earth's magnetic field reversals. In particular, the model produces asymmetric reversals, a positive correlation of field strength and interval length, and a bimodal field distribution. All these features are attributable to the magnetic field dynamics in the vicinity of an exceptional point of the spectrum of the non-selfadjoint dynamo operator. The negative slope of the growth rate curve between the nearby local maximum and the exceptional point makes the system unstable and drives it to the exceptional point and beyond into the oscillatory branch where the sign change happens. A weakness of this reversal model is the apparent necessity to fine-tune the magnetic Reynolds number and/or the radial profile of alpha. In the present paper, it is shown that this fine-tuning is not necessary in the case of higher supercriticality of the dynamo. Numerical examples and physical arguments are compiled to show that, with increasing magnetic Reynolds number, there is strong tendency for the exceptional point and the associated local maximum to move close to the zero growth rate line. Although exemplified again by the spherically symmetric alpha^2 dynamo model, the main idea of this ''self-tuning'' mechanism of saturated dynamos into a reversal-prone state seems well transferable to other dynamos. As a consequence, reversing dynamos might be much more typical and may occur much more frequently in nature than what could be expected from a purely kinematic perspective.Comment: 11 pages, 10 figure