7 research outputs found
Benign childhood epilepsy with centro-temporal spikes: correlation between clinical, cognitive and EEG aspects
Full text linkReview article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases
Get PDFDegree of conversion and temperature increase of a composite resin light cured with an argon laser and blue LED
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Polymorphism of human haptoglobin and its clinical importance
No full textHaptoglobin (Hp) is a plasma glycoprotein, the main biological function of which is to bind free hemoglobin (Hb) and prevent the loss of iron and subsequent kidney damage following intravascular hemolysis. Haptoglobin is also a positive acute-phase protein with immunomodulatory properties. In humans, the HP locus is polymorphic, with two codominant alleles (HP1 and HP2) that yield three distinct genotypes/phenotypes (Hp1-1, Hp2-1 and Hp2-2). The corresponding proteins have structural and functional differences that may influence the susceptibility and/or outcome in several diseases. This article summarizes the available data on the structure and functions of Hp and the possible effects of Hp polymorphism in a number of important human disorders
