2,543 research outputs found
Resources and level of income of farm and rural nonfarm households in eastern Ozarks of Missouri
Missouri Agricultural Experiment Station and Farm Economics Research Division, Agricultural Research Service, U.S. Department of Agriculture cooperating.Digitized 2007 AES.Includes bibliographical references
Acute military psychiatric casualties from the war in Iraq
Background: The view that most military personnel evacuated from war zones are suffering from combat stress reactions, or are otherwise traumatised by the horrors of war, has an impact on all aspects of military psychiatry.
Aims: To delineate the reasons for psychiatric aeromedical evacuation from Iraq from the start of build-up of UK forces in January 2003 until the end of October that year, 6 months after the end of formal hostilities.
Method: A retrospective study was conducted of field and in-patient psychiatric assessments of 116 military personnel evacuated to the UK military psychiatric in-patient facility in Catterick Garrison.
Results: Evacuees were mainly non-combatants (69%). A significant proportion were in reserve service (21%) and had a history of contact with mental health services (37%). Only 3% had a combat stress reaction. In over 85% of cases evacuation was for low mood attributed to separation from friends or family, or difficulties adjusting to the environment.
Conclusions: These findings have implications especially for screening for suitability for deployment, and for understanding any longer-term mental health problems arising in veterans from Iraq
The effect of the ovarian hormones theelin and corporin upon the growth of the mammary gland of the rabbit
Publication authorized August 15, 1932.Digitized 2007 AES.Includes bibliographical references (page 16)
Anatomy of the porcine thyroid
Digitized 2007 AES.Includes bibliographical references (page 10)
Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors
<p>Abstract</p> <p>Background</p> <p>Deletions within the short arm of chromosome 7 are observed in approximately 25% of adult and 10% of Wilms pediatric renal tumors. Within Wilms tumors, the region of interest has been delineated to a 2-Mb minimal region that includes ten known genes. Two of these ten candidate genes, <it>SOSTDC1 </it>and <it>MEOX2</it>, are particularly relevant to tumor development and maintenance. This finding, coupled with evidence that SOSTDC1 is frequently downregulated in adult renal cancer and regulates both Wingless-Int (Wnt)- and bone morphogenetic protein (BMP)-induced signaling, points to a role for SOSTDC1 as a potential tumor suppressor.</p> <p>Methods</p> <p>To investigate this hypothesis, we interrogated the Oncomine database to examine the SOSTDC1 levels in adult renal clear cell tumors and pediatric Wilms tumors. We then performed single nucleotide polymorphism (SNP) and sequencing analyses of <it>SOSTDC1 </it>in 25 pediatric and 36 adult renal tumors. Immunohistochemical staining of patient samples was utilized to examine the impact of <it>SOSTDC1 </it>genetic aberrations on SOSTDC1 protein levels and signaling.</p> <p>Results</p> <p>Within the Oncomine database, we found that SOSTDC1 levels were reduced in adult renal clear cell tumors and pediatric Wilms tumors. Through SNP and sequencing analyses of 25 Wilms tumors, we identified four with loss of heterozygosity (LOH) at 7p and three that affected <it>SOSTDC1</it>. Of 36 adult renal cancers, we found five with LOH at 7p, two of which affected <it>SOSTDC1</it>. Immunohistochemical analysis of SOSTDC1 protein levels within these tumors did not reveal a relationship between these instances of <it>SOSTDC1 </it>LOH and SOSTDC1 protein levels. Moreover, we could not discern any impact of these genetic alterations on Wnt signaling as measured by altered beta-catenin levels or localization.</p> <p>Conclusions</p> <p>This study shows that genetic aberrations near <it>SOSTDC1 </it>are not uncommon in renal cancer, and occur in adult as well as pediatric renal tumors. These observations of <it>SOSTDC1 </it>LOH, however, did not correspond with changes in SOSTDC1 protein levels or signaling regulation. Although our conclusions are limited by sample size, we suggest that an alternative mechanism such as epigenetic silencing of <it>SOSTDC1 </it>may be a key contributor to the reduced SOSTDC1 mRNA and protein levels observed in renal cancer.</p
Contrasting Transient Photocurrent Characteristics for Thin Films of Vacuum-Doped âGreyâ TiO2 and âGreyâ Nb2O5
Photo-catalytic performance for oxide films, here for inkjet-printed TiO2 (ca. 1 Îźm thickness on FTO) and for spray-pyrolysis-coated Nb2O5 (ca. 1 Îźm thickness on FTO), is affected by oxygen vacancies that form during vacuum-heat treatment at 550âŻÂ°C. The effects of the oxygen vacancies are associated with formation of Ti(III) and Nb(IV) sites, respectively, and therefore optically visible as âgreyâ coloration. Photo-electrochemical light-on-off transient experiments are performed in the limit of thin film photoanodes, where front and back illumination result in the same photo-current responses (i.e. with negligible effects from internal light absorption gradients). It is shown that generally the magnitude of photo-currents correlates linearly with light intensity, which is indicative of dominant âphoto-capacitiveâ behaviour. At an applied voltage of 0.4âŻV vs. SCE (in the plateau region of the photo-current responses) the potential and also the pH (going from 1.0âŻM KOH to 0.1âŻM HClO4 in the presence of methanol quencher) have no significant effect on photo-currents; that is, surface chemical/kinetic effects appear to be unimportant and interfacial hole transfer may be rate limiting. Under these conditions (and based on a simplistic mechanistic model) changes in photo-currents introduced by oxygen vacancy doping (detrimental for TiO2 and beneficial for Nb2O5) are assigned primarily to changes in electron mobility
Pediatric trainees\u27 engagement in the online nutrition curriculum: preliminary results
Background: The Pediatric Nutrition Series (PNS) consists of ten online, interactive modules and supplementary educational materials that have utilized web-based multimedia technologies to offer nutrition education for pediatric trainees and practicing physicians. The purpose of the study was to evaluate pediatric trainees\u27 engagement, knowledge acquisition, and satisfaction with nutrition modules delivered online in interactive and non-interactive formats. Methods: From December 2010 through August 2011, pediatric trainees from seventy-three (73) different U. S. programs completed online nutrition modules designed to develop residents\u27 knowledge of counseling around and management of nutritional issues in children. Data were analyzed using SPSS version 19. Both descriptive and inferential statistics were used in comparing interactive versus non-interactive modules. Pretest/posttest and module evaluations measured knowledge acquisition and satisfaction. Results: Three hundred and twenty-two (322) pediatric trainees completed one or more of six modules for a total of four hundred and forty-two (442) accessions. All trainees who completed at least one module were included in the study. Two-way analyses of variance (ANOVA) with repeated measures (pre/posttest by interactive/non-interactive format) indicated significant knowledge gains from pretest to posttest (p \u3c 0.002 for all six modules). Comparisons between interactive and non-interactive formats for Module 1 (N = 85 interactive, N = 95 non-interactive) and Module 5 (N = 5 interactive, N = 16 non-interactive) indicated a parallel improvement from the pretest to posttest, with the interactive format significantly higher than the non-interactive modules (p \u3c .05). Both qualitative and quantitative data from module evaluations demonstrated that satisfaction with modules was high. However, there were lower ratings for whether learning objectives were met with Module 6 (p \u3c 0.03) and lecturer rating (p \u3c 0.004) compared to Module 1. Qualitative data also showed that completion of the interactive modules resulted in higher resident satisfaction. Conclusions: This initial assessment of the PNS modules shows that technology-mediated delivery of a nutrition curriculum in residency programs has great potential for providing rich learning environments for trainees while maintaining a high level of participant satisfaction
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