4 research outputs found

    Development of functional purpose snacks

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    The article provides information on the development of new functional snacks based on local traditional and non-traditional raw materials. The uniqueness of the composition of snacks is associated with the presence in the recipe of dry mare's and camel's milk, as well as fruit and vegetable purees, dry strains of lacto and bifidobacteria, fucoidan and other food ingredients with increased nutritional and biological value. Evaluation of the chemical composition of the nutritional and biological value of snacks indicates their targeted antioxidant, detoxifying and immunostimulating properties. Functional snacks are recommended for use by the general public, including climbers, pilots of civil and military aviation, athletes, as well as in emergencies and conditions that adversely affect human health

    Evaluation of the effectiveness of the influence of photodynamic therapy in the complex treatment of inflammatory processes of oral mucosa

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    Diseases of the oral mucosa remain an important problem of dentistry, as their diagnosis and treatment are significant difficulties. The results of their treatment depend on the possibility of eliminating the etiological factor and the impact on the mechanisms of the disease. Physiotherapy procedures were used in the complex treatment of the oral mucosa. The result of the complex treatment was normalization of the composition of the oral microflora, expressed korregiruyuschee effect on local immunity, as well as an increase in the terms of remission of the disease, compared with patients receiving only conventional treatment.ЗаболСвания слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ Ρ€Ρ‚Π° ΠΎΡΡ‚Π°ΡŽΡ‚ΡΡ Π²Π°ΠΆΠ½ΠΎΠΉ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠΎΠΉ стоматологии, Ρ‚Π°ΠΊ ΠΊΠ°ΠΊ ΠΈΡ… диагностика ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ ΡΠΎΡΡ‚Π°Π²Π»ΡΡŽΡ‚ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Π΅ трудности. Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΈΡ… лСчСния зависят ΠΎΡ‚ возмоТности устранСния этиологичСского Ρ„Π°ΠΊΡ‚ΠΎΡ€Π° ΠΈ воздСйствия Π½Π° ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΡ‹ заболСвания. Π’ комплСксном Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ Ρ€Ρ‚Π° примСнялся физиотСрапСвтичСских ΠΏΡ€ΠΎΡ†Π΅Π΄ΡƒΡ€. Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠΌ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ комплСксного лСчСния явились нормализация состава ΠΌΠΈΠΊΡ€ΠΎΡ„Π»ΠΎΡ€Ρ‹ полости Ρ€Ρ‚Π°, Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½ΠΎΠ΅ ΠΊΠΎΡ€Ρ€ΠΈΠ³ΠΈΡ€ΡƒΡŽΡ‰Π΅Π΅ влияниС Π½Π° мСстный ΠΈΠΌΠΌΡƒΠ½ΠΈΡ‚Π΅Ρ‚, Π° Ρ‚Π°ΠΊΠΆΠ΅ ΡƒΠ²Π΅Π»ΠΈΡ‡Π΅Π½ΠΈΠ΅ сроков рСмиссии заболСвания, ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌΠΈ, ΠΏΠΎΠ»ΡƒΡ‡Π°Π²ΡˆΠΈΠΌΠΈ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ Ρ‚Ρ€Π°Π΄ΠΈΡ†ΠΈΠΎΠ½Π½ΠΎΠ΅ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅

    Ecological significance of conditionally pathogenic microflora in the development of inflammatory periodontal diseases

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    In this article the ecological characteristic of microbiocenosis of the oral cavity is given, which allowed to estimate not only the composition of biocenosis but also its ecological significance in the development of major dental diseases in young people living in a large industrial region on the example of Ufa. The study of microbiocenosis of the oral cavity showed that in this category of persons there are changes in the structure of microorganisms with the domination of opportunistic microorganisms, due to the decrease in the incidence of resident representatives. To characterize the biocenosis, quantitative indicators were supplemented by the state of candidacy or dysbiosis in the direction of candidiasis. It is established that in this category of persons the wealth of species of microorganisms of the oral cavity significantly increased. According to the results of the study, the environmental characteristics of the microbiocenosis of the oral cavity were determined, which allowed to assess its composition and environmental significance in this category of persons living in a disadvantaged environmental situation.Π’ настоящСй ΡΡ‚Π°Ρ‚ΡŒΠ΅ Π΄Π°Π½Π° экологичСская характСристика ΠΌΠΈΠΊΡ€ΠΎΠ±ΠΈΠΎΡ†Π΅Π½ΠΎΠ·Π° полости Ρ€Ρ‚Π°, позволившая ΠΎΡ†Π΅Π½ΠΈΡ‚ΡŒ Π½Π΅ Ρ‚ΠΎΠ»ΡŒΠΊΠΎ состав Π±ΠΈΠΎΡ†Π΅Π½ΠΎΠ·Π° Π½ΠΎ ΠΈ Π΅Π³ΠΎ ΡΠΊΠΎΠ»ΠΎΠ³ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ Π² Ρ€Π°Π·Π²ΠΈΡ‚ΠΈΠΈ основных стоматологичСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ Ρƒ Π»ΠΈΡ† ΠΌΠΎΠ»ΠΎΠ΄ΠΎΠ³ΠΎ возраста, ΠΏΡ€ΠΎΠΆΠΈΠ²Π°ΡŽΡ‰ΠΈΡ… Π² ΠΊΡ€ΡƒΠΏΠ½ΠΎΠΌ ΠΏΡ€ΠΎΠΌΡ‹ΡˆΠ»Π΅Π½Π½ΠΎΠΌ Ρ€Π΅Π³ΠΈΠΎΠ½Π΅ Π½Π° ΠΏΡ€ΠΈΠΌΠ΅Ρ€Π΅ Π³. Π£Ρ„Ρ‹. Π˜Π·ΡƒΡ‡Π΅Π½ΠΈΠ΅ ΠΌΠΈΠΊΡ€ΠΎΠ±ΠΈΠΎΡ†Π΅Π½ΠΎΠ·Π° полости Ρ€Ρ‚Π° ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΎ, Ρ‡Ρ‚ΠΎ Ρƒ Π΄Π°Π½Π½ΠΎΠΉ ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΈ Π»ΠΈΡ† происходят измСнСния структуры ΠΌΠΈΠΊΡ€ΠΎΠΎΡ€Π³Π°Π½ΠΈΠ·ΠΌΠΎΠ² с Π΄ΠΎΠΌΠΈΠ½ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ условно-ΠΏΠ°Ρ‚ΠΎΠ³Π΅Π½Π½Ρ‹Ρ… ΠΌΠΈΠΊΡ€ΠΎΠΎΡ€Π³Π°Π½ΠΈΠ·ΠΌΠΎΠ², Π·Π° счёт сниТСния встрСчаСмости Ρ€Π΅Π·ΠΈΠ΄Π΅Π½Ρ‚Π½Ρ‹Ρ… прСдставитСлСй. для характСристики Π±ΠΈΠΎΡ†Π΅Π½ΠΎΠ·Π° количСствСнныС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ дополнялись состояниСм ΠΊΠ°Π½Π΄ΠΈΠ΄ΠΎΠ½ΠΎΡΠΈΡ‚Π΅Π»ΡŒΡΡ‚Π²Π° ΠΈΠ»ΠΈ дисбиозом Π² сторону ΠΊΠ°Π½Π΄ΠΈΠ΄ΠΎΠ·Π°. УстановлСно, Ρ‡Ρ‚ΠΎ Ρƒ Π΄Π°Π½Π½ΠΎΠΉ ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΈ Π»ΠΈΡ† богатство Π²ΠΈΠ΄ΠΎΠ² ΠΌΠΈΠΊΡ€ΠΎΠΎΡ€Π³Π°Π½ΠΈΠ·ΠΌΠΎΠ² полости Ρ€Ρ‚Π° достовСрно ΡƒΠ²Π΅Π»ΠΈΡ‡ΠΈΠ²Π°Π»ΠΎΡΡŒ. По Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Π°ΠΌ исслСдования ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Π° экологичСская характСристика ΠΌΠΈΠΊΡ€ΠΎΠ±ΠΈΠΎΡ†Π΅Π½ΠΎΠ·Π° полости Ρ€Ρ‚Π°, позволившая ΠΎΡ†Π΅Π½ΠΈΡ‚ΡŒ Π΅Π³ΠΎ состав ΠΈ ΡΠΊΠΎΠ»ΠΎΠ³ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ Ρƒ Π΄Π°Π½Π½ΠΎΠΉ ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΈ Π»ΠΈΡ† ΠΏΡ€ΠΎΠΆΠΈΠ²Π°ΡŽΡ‰ΠΈΡ… Π² условиях Π½Π΅Π±Π»Π°Π³ΠΎΠΏΠΎΠ»ΡƒΡ‡Π½ΠΎΠΉ экологичСской обстановки

    The interrelation between oral microbiota and factors of local immunity in the development of inflammatory periodontal diseases

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    The article presents the current understanding of the state of microbiota of the oral cavity, its species diversity, the properties of microbial associations and their impact on the clinical state of periodontal tissues. The effectiveness of complex microbiological studies of smears from the oral cavity and immunological methods of studies of oral fluid samples in the diagnosis of the risk of development and weighting of inflammatory periodontal diseases depending on the revealed violation of the oral microbiota is analyzed. In 17 (35.42+0.05%) patients with TRC, yeast - like fungi of the genus Candida spp (C. albicans) were found in oral fluid samples in an average of 103 -104 CFU/ml in a state of chronic candidiasis (p < 0.05), in chronic gingivitis (CG) on average in 376 (61.44+0.05%) of the examined persons, including pseudomycelial forms were found in 124 patients (32.98+0.03%), yeast form in 252 67.02+0.05%), indicating a dysbiotic shift towards candidiasis, an average of 104-105 CFU/ml (p< 0.05).Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ ΠΈΠ·Π»ΠΎΠΆΠ΅Π½ΠΎ соврСмСнноС прСдставлСниС ΠΎ состоянии ΠΌΠΈΠΊΡ€ΠΎΠ±ΠΈΠΎΡ‚Ρ‹ полости Ρ€Ρ‚Π°, Π΅Π³ΠΎ Π²ΠΈΠ΄ΠΎΠ²ΠΎΠΌ Ρ€Π°Π·Π½ΠΎΠΎΠ±Ρ€Π°Π·ΠΈΠΈ, свойствах ΠΌΠΈΠΊΡ€ΠΎΠ±Π½Ρ‹Ρ… ассоциаций ΠΈ ΠΈΡ… влиянии Π½Π° клиничСскоС состояниС Ρ‚ΠΊΠ°Π½Π΅ΠΉ ΠΏΠ°Ρ€ΠΎΠ΄ΠΎΠ½Ρ‚Π°. ΠŸΡ€ΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π½Π° ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ примСнСния комплСксных микробиологичСских исслСдований ΠΌΠ°Π·ΠΊΠΎΠ² с полости Ρ€Ρ‚Π° ΠΈ иммунологичСских ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠ² исслСдований ΠΏΡ€ΠΎΠ± Ρ€ΠΎΡ‚ΠΎΠ²ΠΎΠΉ Тидкости Π² диагностикС риска развития ΠΈ утяТСлСния Π²ΠΎΡΠΏΠ°Π»ΠΈΡ‚Π΅Π»ΡŒΠ½Ρ‹Ρ… Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΏΠ°Ρ€ΠΎΠ΄ΠΎΠ½Ρ‚Π° Π² зависимости ΠΎΡ‚ выявлСнного Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠΈ ΠΌΠΈΠΊΡ€ΠΎΠ±ΠΈΠΎΡ‚Ρ‹ полости Ρ€Ρ‚Π°. Π£ 17 (35,42+0,05%) ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с КИП Π² ΠΏΡ€ΠΎΠ±Π°Ρ… Ρ€ΠΎΡ‚ΠΎΠ²ΠΎΠΉ Тидкости ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Ρ‹ Π΄Ρ€ΠΎΠΆΠΆΠ΅ΠΏΠΎΠ΄ΠΎΠ±Π½Ρ‹Π΅ Π³Ρ€ΠΈΠ±Ρ‹ Ρ€ΠΎΠ΄Π° Candida spp (Π‘. albicans) Π² срСднСм 103-104 ΠšΠžΠ•/ΠΌΠ» Π² состоянии хроничСского ΠΊΠ°Π½Π΄ΠΈΠ΄ΠΎΠ½ΠΎΡΠΈΡ‚Π΅Π»ΡŒΡΡ‚Π²Π° (Ρ€ < 0,05), ΠΏΡ€ΠΈ хроничСском Π³ΠΈΠ½Π³ΠΈΠ²ΠΈΡ‚Π΅ (Π₯Π“) Π² срСднСм Ρƒ 376 (61,44Β±0,05%) обслСдованных Π»ΠΈΡ†, Π² Ρ‚ΠΎΠΌ числС ΠΏΡΠ΅Π²Π΄ΠΎΠΌΠΈΡ†Π΅Π»ΠΈΠ°Π»ΡŒΠ½Ρ‹Π΅ Ρ„ΠΎΡ€ΠΌΡ‹ ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Ρ‹ Ρƒ 124 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² (32,98+0,03%), дроТТСвая Ρ„ΠΎΡ€ΠΌΠ° Ρƒ 252 (67,02+0,05%), Ρ‡Ρ‚ΠΎ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΠΎΠ²Π°Π»ΠΎ ΠΎ дисбиотичСском сдвигС Π² сторону ΠΊΠ°Π½Π΄ΠΈΠ΄ΠΎΠ·Π°, Π² срСднСм Π΄ΠΎ 104 -105 ΠšΠžΠ•/ΠΌΠ» (Ρ€< 0,05)
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