The Poetry of Dialogue: Kanshi, Haiku and Media in Meiji Japan, 1870-1900

This dissertation examines the influence of `poetic sociality' during Japan's Meiji period (1867-1912). `Poetic sociality' denotes a range of practices within poetic composition that depend upon social interaction among individuals, most importantly the tendency to practice poetry as a group activity, pedagogical practices such as mutual critique and the master-disciple relationship, and the exchange among individual poets of textually linked forms of verse. Under the influence of modern European notions of literature, during the late Meiji period both prose fiction and the idea of literature as originating in the subjectivity of the individual assumed hegemonic status. Although often noted as a major characteristic of pre-modern poetry, poetic sociality continued to be enormously influential in the literary and social activities of 19th century Japanese intellectuals despite the rise of prose fiction during late Meiji, and was fundamental to the way in which poetry was written, discussed and circulated. One reason for this was the growth of a mass-circulation print media from early Meiji onward, which provided new venues for the publication of poetry and enabled the expression of poetic sociality across distance and outside of face-to-face gatherings. With poetic exchange increasingly taking place through newspapers and literary journals, poetic sociality acquired a new and openly political aspect. Poetic exchanges among journalists and readers served in many cases as vehicles for discussion of political topics such as governmental corruption, international relations and environmental disasters, an aspect of Meiji-era poetry that has received comparatively little attention

Impacts of Irrigation Development on Anadromous Fish in the Yakima River Basin, Washington

Prior to Euroamerican development, the Yakima River Basin was a major producer of salmon. Total runs of approximately 800,000 have declined to 3,000-5,000, or less than 1% of original run size. Three species are extinct in the basin, including summer chinook, coho, and sockeye. Irrigation development, including the construction of unscreened diversions, the blockage of spawning and rearing habitat by reservoir dams, and the dewatering of spawning and rearing habitat, began in the mid-1800\u27s and today totals approximately 500,000 acres. Historical records provide a wealth of information documenting irrigation development and its consequences on anadromous fish populations

The GOJO Smartlink Observation System: Research for Adoption

This research project sought to provide GOJO Industries, Inc. with strategic recommendations for improving sales of their SMARTLINK Observation (OBV) hand hygiene compliance monitoring mobile application. The two required steps for building recommendations were to analyze the status of the hand hygiene compliance monitoring market (as of 2017) and gain insight on the needs of nurses, doctors, and other healthcare directors in hospitals and urgent care facilities. In conjunction with GOJO Industries, Inc., the viability of a subscription-based mobile application for monitoring was tested. Employees of several different healthcare facilities were interviewed about their current methods and practices for compliance monitoring. Their pain points, suggestions, and thoughts on a mobile application solution were all documented. Information was also gathered from hospital systems that currently use GOJO\u27s Smartlink OBV application. Upon aggregating all of the interview responses, four strategic recommendations for selling the GOJO Smartlink app were formulated. The four suggestions: 1. Improve existing reporting capabilities and features.2. Create a hygiene compliance standard and reward for hospitals to display. 3. Bundle the application with other GOJO products (purell, the fully automated dispensing systems, etc.) and offer a freemium version of the app. 4. Modify the application for use in other markets, such as restuarants, chemical labs, schools, and factories

Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration

Alterations in mitochondrial dynamics (fission, fusion and movement) are implicated in many neurodegenerative diseases, from rare genetic disorders such as Charcot-Marie-Tooth disease, to common conditions including Alzheimer’s disease. However, the relationship between altered mitochondrial dynamics and neurodegeneration is incompletely understood. Here we show that disease associated MFN2 proteins suppressed both mitochondrial fusion and transport, and produced classic features of segmental axonal degeneration without cell body death, including neurofilament filled swellings, loss of calcium homeostasis, and accumulation of reactive oxygen species. By contrast, depletion of Opa1 suppressed mitochondrial fusion while sparing transport, and did not induce axonal degeneration. Axon degeneration induced by mutant MFN2 proteins correlated with the disruption of the proper mitochondrial positioning within axons, rather than loss of overall mitochondrial movement, or global mitochondrial dysfunction. We also found that augmenting expression of MFN1 rescued the axonal degeneration caused by MFN2 mutants, suggesting a possible therapeutic strategy for Charcot-Marie-Tooth disease. These experiments provide evidence that the ability of mitochondria to sense energy requirements and localize properly within axons is key to maintaining axonal integrity, and may be a common pathway by which disruptions in axonal transport contribute to neurodegeneration