125 research outputs found

    Creating Working Value Evaluation Model WVEM

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    The authors create a Working Value Evaluation Model WVEM for labor valuation by using statistical science that allows manufacturers to visualize the performance of labor. We verify the effectiveness of this model at auto manufactures and others

    In vitro perforation of human epithelial carcinoma cell with antibody-conjugated biodegradable microspheres illuminated by a single 80 femtosecond near-infrared laser pulse

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    Pulsed laser interaction with small metallic and dielectric particles has been receiving attention as a method of drug delivery to many cells. However, most of the particles are attended by many risks, which are mainly dependent upon particle size. Unlike other widely used particles, biodegradable particles have advantages of being broken down and eliminated by innate metabolic processes. In this paper, the perforation of cell membrane by a focused spot with transparent biodegradable microspheres excited by a single 800 nm, 80 fs laser pulse is demonstrated. A polylactic acid (PLA) sphere, a biodegradable polymer, was used. Fluorescein isothiocyanate (FITC)-dextran and short interfering RNA were delivered into many human epithelial carcinoma cells (A431 cells) by applying a single 80 fs laser pulse in the presence of antibody-conjugated PLA microspheres. The focused intensity was also simulated by the three-dimensional finite-difference time-domain method. Perforation by biodegradable spheres compared with other particles has the potential to be a much safer phototherapy and drug delivery method for patients. The present method can open a new avenue, which is considered an efficient adherent for the selective perforation of cells which express the specific antigen on the cell membrane

    A Study Of Building An Intellectual Working Value Improvement Model IWV-IM

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    In order for Japan’s manufacturing industry to succeed amidst today’s global competition, companies must further increase the quality of tasks performed by on-site workers (worker dedication), thereby enabling them to create products with superior QCD. To this end, the authors investigated the problems currently facing manufacturing sites and identified their key factors. They then used these factors to formulate the Intellectual Working Value Improvement Model“IWV-IM”designed to improve working value and increase worker dedication. The effectiveness of this model was then verified

    DETERMINATION OF DICARBOXYLIC DEGRADATION PRODUCTS OF NONYLPHENOL POLYETHOXYLATES IN WATER SAMPLES BY SPE AND GC-MS AFTER METHYLATION

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    Joint Research on Environmental Science and Technology for the Eart
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