Microcraters in aluminum foils exposed by Stardust

We will present preliminary results on the nature and size frequency distribution of microcraters that formed in aluminum foils during the flyby of comet Wild 2 by the Stardust spacecraft

Stream depletion rate with horizontal or slanted wells in confined aquifers near a stream

Pumping in a vertical well may produce a large drawdown cone near the well. In this paper, the solution is first developed for describing the groundwater flow associated with a point source in a confined aquifer near a stream. Based on the principle of superposition, analytical solutions for horizontal and slanted wells are then developed by integrating the point source solution along the well axis. The solutions can be simplified to quasi-steady solutions by neglecting the exponential terms to describe the late-time drawdown, which can provide useful information in designing horizontal well location and length. The direction of the well axis can be determined from the best SDR subject to the drawdown constraint. It is found that hydraulic conductivity in the direction perpendicular to the stream plays a crucial role in influencing the time required for reaching quasi-steady SDR. In addition, the effects of the well length as well as the distance between the well and stream on the SDR are also examined

Deletions of 11q22.3-q25 Are Associated with Atypical Lung Carcinoids and Poor Clinical Outcome

Carcinoids are slow-growing neuroendocrine tumors that, in the lung, can be subclassified as typical (TC) or atypical (AC). To identify genetic alterations that improve the prediction of prognosis, we investigated 34 carcinoid tumors of the lung (18 TCs, 15 ACs, and 1 unclassified) by using array comparative genomic hybridization (array CGH) on 3700 genomic bacterial artificial chromosome arrays (resolution = 1 Mb) and losses at 1p, 2q, 10q, and 11q; and iii) 11q deletions in 8 of 15 ACs versus 1 of 18 TCs = 0.004), which was confirmed via fluorescence in situ hybridization. The four critical regions of interest in 45% ACs or more comprised 11q14.1, 11q22.1-q22.3, 11q22.3-q23.2, and 11q24.2-q25, all telomeric of MEN1 at 11q13. Results were correlated with patient clinical data and long-term follow-up. Thus, there is a strong association of 11q223-q25 loss with poorer prognosis, alone or in combination with absence of 9q34.11 alterations (P = 0.0022 and P = 0.00026, respectively). (Am J Pathol 2011, 179:1129-1137; DOI: 10.1016/j.ajpath.2011.05.028