A γA-Crystallin Mouse Mutant Secc with Small Eye, Cataract and Closed Eyelid

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Lymph node density in silicosis: its relationship with lung function and clinical parameters

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Plasma bradykinin level and angiotensin-converting enzyme gene polymorphism in hypertensive patients

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Outcomes of Vestibular Schwannoma undergoing operation or radiosurgery - a single center experience

Oral-Poster Presentation 2Meeting Theme: Degenerative Lumbar SpineBACKGROUND: Different modalities have been used for treating vestibular schwannoma. To evaluate the treatment modailities and their respective outcome and complications of a series of patients with acoustic neuroma. MATERIALS AND METHODS: A restropective single-center study of 80 patients from 2007 to 2014 with acoustic neuroma were carried out. Patients with neurofibromatosis II and those with incomplete information were excluded. Their presenting symptoms, tumour size at diagnosis, cranial nerve deficit before and after treatment, the treatment modality, the type of surgical …published_or_final_versio

Randomised trial of candesartan and enalapril (RACE) in the treatment of hypertension - final results

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First genome sequences of buffalo coronavirus from water buffaloes in Bangladesh

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Implantable atrial defibrillator prevented atrial stunning and improved ventricular funciton after cardioversion from atrial fibrillation

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Symptomatic hyperperfusion after surgical revascularization for moyamoya disease: incidence, natural history and preictors

Conference Theme: Brain Attack: A New EraFree Paper 8AIM: To study the incidence, natural history and predictors for post-revascularization symptomatic hyperperfusion in moyamoya patient ...postprin

The Nucleosome Assembly Protein TSPYL2 Regulates the Expression of NMDA Receptor Subunits GluN2A and GluN2B

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Novel adaptive beam-dependent margins for additional OAR sparing.

Margins are employed in radiotherapy treatment planning to mitigate the dosimetric effects of geometric uncertainties for the clinical target volume (CTV). Unfortunately, whilst the use of margins can increase the probability that sufficient dose is delivered to the CTV, it can also result in delivering high dose of radiation to surrounding organs at risk (OARs). We expand on our previous work on beam-dependent margins and propose a novel adaptive margin concept, where margins are moulded away from selected OARs for better OAR-high-dose sparing, whilst maintaining similar dose coverage probability to the CTV. This, however, comes at a cost of a larger irradiation volume, and thus can negatively impact other structures. We investigate the impact of the adaptive margin concept when applied to prostate radiotherapy treatments, and compare treatment plans generated using our beam-dependent margins without adaptation, with adaption from the rectum and with adaptation from both the rectum and bladder. Five prostate patients were used in this planning study. All plans achieved similar dose coverage probability, and were able to ensure at least 90% population coverage with the target receiving at least 95% of the prescribed dose to [Formula: see text]. We observed overall better high-dose sparing to OARs that were considered when using the adapted beam-dependent PTVs, with the degree of sparing dependent on both the number of OARs under consideration as well as the relative position between the CTV and the OARs