220 research outputs found
Ex vivo evaluation of a Taylor-Couette flow, immobilized heparinase I device for clinical application
A fine structural study of divalent cation-mediated epithelial union with connective tissue in human oral mucosa
Following incubation in an isotonic saline solution containing 20 mM EDTA, human oral mucosa may be separated into its epithelial and connective tissue components. Ultrastructural study of the separated tissues reveals that the plane of separation is through the lamina lucida. Hemidesmosomal structure is altered by the separation process: the peripheral density is absent but a fine, generally filamentous material remains associated with the outer membrane leaflet of the hemidesmosome. Desmosome structure is not altered. An intact lamina densa remains attached to the connective tissue fragment. Oral mucosa incubated in EDTA-saline containing calcium, or its return to a divalent cation-supplemented medium after treatment with EDTA, prevents separation. By maintaining the structural integrity of the hemidesmosome, divalent cations appear to play a principal role in uniting oral mucosal epithelium to the lamina propria.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/49659/1/1001330406_ftp.pd
Effects of Compound 48/80 on Platelets: Structural Alterations and Inhibition of Aggregation
Taiwan as an Entrepôt in East Asia in the Seventeenth Century
Taiwan is strategically situated within East Asia, but little is known of it until the sixteenth century. The Chinese spread far and wide throughout Asia even before the Christian era, but allowed this large and fertile island lying so close to the Mainland to remain in relative obscurity until the middle of the Ming dynasty (1368–1644). The cause of this isolation is that Taiwan had no large quantities of marketable products to attract traders and that the island still lay outside the network of Asian trade routes of the time.</jats:p
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