8,130 research outputs found
Coulomb blockade and quantum tunnelling in the low-conductivity phase of granular metals
We study the effects of Coulomb interaction and inter-grain quantum
tunnelling in an array of metallic grains using the phase-functional approach
for temperatures well below the charging energy of individual
grains yet large compared to the level spacing in the grains. When the
inter-grain tunnelling conductance , the conductivity in
dimensions decreases logarithmically with temperature
(), while for ,
the conductivity shows simple activated behaviour ().
We show, for bare tunnelling conductance , that the parameter
determines the competition between
charging and tunnelling effects. At low enough temperatures in the regime
, a charge is shared among a finite
number of grains, and we find a soft
activation behaviour of the conductivity, , where is the effective
coordination number of a grain.Comment: 11 pages REVTeX, 3 Figures. Appendix added, replaced with published
versio
Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline.
Oligodendrocyte progenitors (OPs) arise from distinct ventral and dorsal domains within the ventricular germinal zones of the embryonic CNS. The functional significance, if any, of these different populations is not known. Using dual-color reporter mice to distinguish ventrally and dorsally derived OPs, we show that, in response to focal demyelination of the young adult spinal cord or corpus callosum, dorsally derived OPs undergo enhanced proliferation, recruitment, and differentiation as compared with their ventral counterparts, making a proportionally larger contribution to remyelination. However, with increasing age (up to 13 months), the dorsally derived OPs become less able to differentiate into mature oligodendrocytes. Comparison of dorsally and ventrally derived OPs in culture revealed inherent differences in their migration and differentiation capacities. Therefore, the responsiveness of OPs to demyelination, their contribution to remyelination, and their susceptibility to age-associated functional decline are markedly dependent on their developmental site of origin in the developing neural tube.A.H.C. was funded by a Wellcome Trust Integrated Training Fellowship (096384/Z/11/Z). Work in R.J.M.F.’s laboratory was funded by The UK Multiple Sclerosis Society (941) and by a core support grant from the Wellcome Trust and MRC to the Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute. Work in W.D.R.’s laboratory was funded by the Medical Research Council (G0800575), the Wellcome Trust (WT100269AIA), and the European Research Council (293544).This is the final version of the article. It first appeared from Cell Press via http://dx.doi.org/10.1016/j.celrep.2016.03.06
Enhanced Room Temperature Coefficient of Resistance and Magneto-resistance of Ag-added La0.7Ca0.3-xBaxMnO3 Composites
In this paper we report an enhanced temperature coefficient of resistance
(TCR) close to room temperature in La0.7Ca0.3-xBaxMnO3 + Agy (x = 0.10, 0.15
and y = 0.0 to 0.40) (LCBMO+Ag) composite manganites. The observed enhancement
of TCR is attributed to the grain growth and opening of new conducting channels
in the composites. Ag addition has also been found to enhance intra-granular
magneto-resistance. Inter-granular MR, however, is seen to decrease with Ag
addition. The enhanced TCR and MR at / near room temperature open up the
possibility of the use of such materials as infrared bolometric and magnetic
field sensors respectively.Comment: 22 pages of Text +
Figs:comments/suggestions([email protected]
In-vitro antioxidant and in-vivo anti-inflammatory activities of aerial parts of Cassia species
AbstractCassia species are native to Southeast Asia and sub-Saharan Africa and are commonly used as food and in a broad variety of medicinal applications. Cassia species are widely used in India, but there are few reports in the literature of studies on its chemical compositions and biological properties. In this study, the antioxidant and anti-inflammatory activities of two plants of Cassia species namely Cassia siamea (Lam.) and Cassia javanica (Linn.) were evaluated and the total phenolic compounds and flavonoid contents were determined.The antioxidant activity of the extracts was measured using scavenging of 2,2′-Diphenyl-1-picrylhydrazyl hydrate (DPPH), bleaching of β-carotene and % inhibition of H2O2. The anti-inflammatory activity was evaluated using carrageenan induced paw edema method on Wistar albino rats. The etahnolic extracts of aerial parts of C. siamea and C. javanica were evaluated for in vivo anti-inflammatory activity against the animal model of female Wistar albino rats. Ethanol extracts showed significant and dose-dependent anti-inflammatory effects. The contents of flavonoids and total phenolic compounds could be correlated with the antioxidant and anti-inflammatory activities observed for C. siamea and C. javanica. Our findings suggest that aerial parts of C. siamea and C. javanica contain potential antioxidant and anti-inflammatory compounds, which could be tested as drug candidates against oxidative and inflammation-related pathological processes in medicinal chemistry studies
Nonlinear mode coupling and energetics of driven magnetized shear-flow turbulence
To comprehensively understand saturation of two-dimensional (D) magnetized
Kelvin-Helmholtz-instability-driven turbulence, energy transfer analysis is
extended from the traditional interaction between scales to include eigenmode
interactions, by using the nonlinear couplings of linear eigenmodes of the
ideal instability. While both kinetic and magnetic energies cascade to small
scales, a significant fraction of turbulent energy deposited by unstable modes
in the fluctuation spectrum is shown to be re-routed to the conjugate-stable
modes at the instability scale. They remove energy from the forward cascade at
its inception. The remaining cascading energy flux is shown to attenuate
exponentially at a small scale, dictated by the large-scale stable modes.
Guided by a widely used instability-saturation assumption, a general
quasilinear model of instability is tested by retaining all nonlinear
interactions except those that couple to the large-scale stable modes. These
complex interactions are analytically removed from the magnetohydrodynamic
equations using a novel technique. Observations are: an explosive large-scale
vortex separation instead of the well-known merger of D, a dramatic
enhancement in turbulence level and spectral energy fluxes, and a reduced
small-scale dissipation length-scale. These show critical role of the stable
modes in instability saturation. Possible reduced-order turbulence models are
proposed for fusion and astrophysical plasmas, based on eigenmode-expanded
energy transfer analyses.Comment: Selected by the editors of Physics of Plasmas as a Featured article.
https://doi.org/10.1063/5.015656
Linear Stability of Triangular Equilibrium Points in the Generalized Photogravitational Restricted Three Body Problem with Poynting-Robertson Drag
In this paper we have examined the linear stability of triangular equilibrium
points in the generalised photogravitational restricted three body problem with
Poynting-Robertson drag. We have found the position of triangular equilibrium
points of our problem. The problem is generalised in the sense that smaller
primary is supposed to be an oblate spheroid. The bigger primary is considered
as radiating. The equations of motion are affected by radiation pressure force,
oblateness and P-R drag. All classical results involving photogravitational and
oblateness in restricted three body problem may be verified from this result.
With the help of characteristic equation, we discussed the stability. Finally
we conclude that triangular equilibrium points are unstable.Comment: accepted for publication in Journal of Dynamical Systems & Geometric
Theories Vol. 4, Number 1 (2006
Sustainability of crop production from polluted lands
Sustainable food production for a rapidly growing global population is a major challenge of this century. In order to meet the demand for food production, an additional land area of 2.7 to 4.9 Mha year -1 will be required for agriculture. However, one third of arable lands are already contaminated, therefore the use of polluted lands will have to feature highly in modern agriculture. The use of such lands comes however with additional challenges and suitable agrotechnological interventions are essential for ensuring the safety and sustainability of relevant production system. There are also other issues to consider such as, cost benefit analysis, the possible entry of pollutants into to the phytoproducts, certification and marketing of such products, in order to achieve a the large scale exploitation of polluted land
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