Advanced Control of the dynamic voltage restorer for mitigating voltage sags in power systems

The paper presents a vector control with two cascaded loops to improve the properties of Dynamic Voltage Restorer (DVR) to minimize Voltage Sags on the grid. Thereby, a vector controlled structure was built on the rotating dq-coordinate system with the combination of voltage control and the current control. The proposed DVR control method is modelled using MATLAB-Simulink. It is tested using balanced/ unbalanced voltage sags as well as fluctuant and distorted voltages. As a result, by using this controlling method, the dynamic characteristics of the system have been improved significantly. The system performed with higher accuracy, faster response and lower distortion in the voltage sags compensation. The paper presents real time experimental results to verify the performance of the proposed method in real environments

Improving Traffic Efficiency in a Road Network by Adopting Decentralised Multi-Agent Reinforcement Learning and Smart Navigation

In the future, mixed traffic flow will consist of human-driven vehicles (HDVs) and connected autonomous vehicles (CAVs). Effective traffic management is a global challenge, especially in urban areas with many intersections. Much research has focused on solving this problem to increase intersection network performance. Reinforcement learning (RL) is a new approach to optimising traffic signal lights that overcomes the disadvantages of traditional methods. In this paper, we propose an integrated approach that combines the multi-agent advantage actor-critic (MA-A2C) and smart navigation (SN) to solve the congestion problem in a road network under mixed traffic conditions. The A2C algorithm combines the advantages of value-based and policy-based methods to stabilise the training by reducing the variance. It also overcomes the limitations of centralised and independent MARL. In addition, the SN technique reroutes traffic load to alternate paths to avoid congestion at intersections. To evaluate the robustness of our approach, we compare our model against independent-A2C (I-A2C) and max pressure (MP). These results show that our proposed approach performs more efficiently than others regarding average waiting time, speed and queue length. In addition, the simulation results also suggest that the model is effective as the CAV penetration rate is greater than 20%

Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study

Early neurological deterioration (END) is progressive neurological deterioration with an increase in NIHSS score of 2 points or more in the first 72 hours from the onset of acute ischemic stroke. END increases the risk of poor clinical outcomes at day 90 of ischemic stroke. We will study the frequency, predictors, and outcomes of patients with END in a case-control study at a comprehensive stroke centre in Vietnam. of the design is a descriptive observational study, longitudinal follow-up of patients with minor stroke hospitalized at the Stroke Center of Bach Mai Hospital from December 1, 2023, to December 1, 2024. Minor stroke patients characterized by NIHSS score ≤ 5 hospitalized within 24 hours of symptom onset will be recruited. The estimated END rate is about 30%, relative accuracy ε = 0.11, 95% reliability, expected 5% of patients lost data or follow-up, and an estimated sample size of 779 patients. This study will help determine the END rate in patients with minor stroke and related factors, thereby building a prognostic model for END. Our study determined the END rate in patients with minor stroke in Vietnam and also proposed risk factors for minor stroke management and treatment

Sand Spit Morphology at an Inlet on Phu Quoc Island, Vietnam

Tidal inlets with attached sand spits are a very common coastal landform. Since the evolution of sand spits along coastlines influence the social-economic development of local coastal areas, sand spits have become the objects of numerous studies. However, previous studies have mainly focused on sand spits that are usually in the scale of hundreds of meters in width, whilst knowledge about the evolution of smaller-scale sand spits still remains limited. Therefore, in this study, the morphological change of a small and unexplored sand spit in front of Song Tranh Inlet on the west coast of Phu Quoc Island, Vietnam is investigated. Satellite images are first used to observe the morphological change of the sand spit and calculate the longshore sediment transport rates (LSTR) along the sand spit. Waves and beach sediments are collected at the study site to calculate the longshore sediment transport rate using the CERC formula. It is found that there is a seasonal variation in the evolution of the sand spit at Song Tranh Inlet. The longshore sediment transport rates along the spit calculated by image analysis are 39,000 m$^3$/year, 66,000 m$^3$/year, and 40,000 m$^3$/year, whilst the longshore sediment transport rate calculated by the CERC formula is 72,000 m$^3$/year. This study aims to contribute to the methodology for investigating the evolutions of small sand spits and, specifically, sustainable coastal management for Phu Quoc Island, which is well-known as the Pearl Island of Vietnam

Isolation and screening marine fungi with antimicrobial activity from samples collected in Nha Trang bay, VietNam

The marine environment is an extremely complex ecosystem and contains a broad spectrum of fungal diversity. Marine fungi have been shown to be tremendous sources for new and biologically active secondary metabolites. The present study aims to isolate and screen antimicrobial properties of 100 fungus strains from different marine sources including seaweeds, soft corals, sponges and sediment collected at Nha Trang Bay, Vietnam. In preliminary experiments, the crude extracts of these fungal isolates with ethyl acetate were screened for their antimicrobial activity against the human microbial pathogens including Bacillus cereus ATCC 11778, Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Listeria monocytogenes ATCC 19111, Streptococcus faecalis ATCC 19433 and Candida albicans ATCC 10231 by the disc diffusion method. Among the 100 isolates, 59 strains exhibited antimicrobial activity against at least two tested pathogens, that 57% against S. aureus, 50% against L. monocytogenes, 49% against B. cereus, 45% against S. faecalis, 7% against E. coli, 5% against C. albicans, and only 2% against P. aeruginosa. The present study has revealed the presence of high numbers of marine fungi from Nha Trang waters having antimicrobial properties and they need to be investigated further for natural bioactive products

Effect of cultural conditions on antimicrobial activity of marine-derived fungus Penicillium chrysogenum

Marine fungi are a potential source of structurally diversified bioactive secondary metabolites that are not found in terrestrial sources. In our continuous investigation to search new antimicrobial agents from marine-derived fungi, we isolated fungal strain 045-357-2 from a soft coral sample collected from Ca Na bay, Ninh Thuan, Vietnam. The strain showed high antibacterial activity and was selected for further study. According to Internal Transcribed Spacer (ITS) rDNA molecular methods, the fungus was identified as Penicillium chrysogenum 045-357-2 and had a 100% homology (600/600 bp) with a GenBank sequence from a reference P. chrysogenum strain (NCBI accession no. EF200090). In the present investigation, the fungus was studied on effect of different culture incubation period, pH and salinity for antimicrobial activity against pathogenic microbes including Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Streptococcus faecalis, Listeria monocytogenes, and Candida albicans. The ethyl acetate extracts of culture medium of the fungal isolate were determined antimicrobial activity by disc diffusion assay. The results showed that the optimum antimicrobial activity of the fungal strain P. chrysogenum 045-357-2 was obtained in medium containing 20 g rice, 20 mg yeast extract, 10 mg KH2PO4 , and 40 mL natural seawater at 30oC on the 14th day of incubation. The strain also exhibited highest antimicrobial activity in the medium at initial pH 6.0 – 8.0 and salinity of 35 g/L. The findings indicate that cultural conditions significantly influenced on antimicrobial activity of the studied fungus. The optimization is potential use for further study on the mass cultivation and isolation of bioactive compounds for this fungus

Anatomical Characteristics and Variants of Prostatic Artery in Patients of Benign Hyperplasia Prostate by Digital Subtraction Angiography

AIM: This work is aimed to describe anatomical features and variants of the prostatic artery (PA) using digital subtraction angiography (DSA). METHODS: This is a descriptive statistic study. We reviewed the DSA of 348 patients, who had a PA embolisation to reduce the benign prostatic hyperplasia (BPH) symptoms at Radiology Department of Bach Mai Hospital from Oct – 2014 to Oct – 2018. RESULTS: PA was found at 660 pelvic halves, of which 30 pelvic halves (4.5%) had two PAs, 630 pelvic halves had one PA. In terms of the origin of PA, in total 690 PAs, the percentage of type 1, 2, 3, 4 and 5 was successively 33.9%, 13.9%, 18.3%, 23.9% and 10.4%, respectively. Atherosclerosis of PA observed in 20.9%. The ‘corkscrew’ pattern was found in 30.4%. The average diameter of PA was 1.5 ± 0.34mm. The anastomosis of PA with surrounding arteries was common. PA may supply rectum (6.1%), seminal vesical (9.6%), bladder (5.2%), contralateral prostatic parenchyma (13.0%), surrounding soft-tissues (3.5%). CONCLUSION: The common trunk with SVA superior vesical artery was the most common origin of PA. Anastomoses of PA with surrounding tissues were complex

Simultaneously induced mutations in eIF4E genes by CRISPR/Cas9 enhance PVY resistance in tobacco

Tobacco is an important commercial crop and a rich source of alkaloids for pharmaceutical and agricultural applications. However, its yield can be reduced by up to 70% due to virus infections, especially by a potyvirus Potato virus Y (PVY). The replication of PVY relies on host factors, and eukaryotic translation initiation factor 4Es (eIF4Es) have already been identified as recessive resistance genes against potyviruses in many plant species. To investigate the molecular basis of PVY resistance in the widely cultivated allotetraploid tobacco variety K326, we developed a dual guide RNA CRISPR/Cas9 system for combinatorial gene editing of two clades, eIF4E1 (eIF4E1-S and eIF4E1-T) and eIF4E2 (eIF4E2-S and eIF4E2-T) in the eIF4E gene family comprising six members in tobacco. We screened for CRISPR/Cas9-induced mutations by heteroduplex analysis and Sanger sequencing, and monitored PVY(O) accumulation in virus challenged regenerated plants by DAS-ELISA both in T0 and T1 generations. We found that all T0 lines carrying targeted mutations in the eIF4E1-S gene displayed enhanced resistance to PVY(O) confirming previous reports. More importantly, our combinatorial approach revealed that eIF4E1-S is necessary but not sufficient for complete PVY resistance. Only the quadruple mutants harboring loss-of-function mutations in eIF4E1-S, eIF4E1-T, eIF4E2-S and eIF4E2-T showed heritable high-level resistance to PVY(O) in tobacco. Our work highlights the importance of understanding host factor redundancy in virus replication and provides a roadmap to generate virus resistance by combinatorial CRISPR/Cas9-mediated editing in non-model crop plants with complex genomes

HAEMAGGLUTINATION ACTIVITY OF THE EXTRACTS FROM SOME VIETNAM MARINE INVERTEBRATES

Aqueous extracts from 21 species of Vietnam marine invertebrates, including 11 bivalve and 10 gastropod species, were examined for haemagglutination activity using native and enzyme-treated different animal and human erythrocytes. The 8 bivalve and 10 gastropod species were found to have haemagglutinination activities toward at least one type of erythrocyte tested. A total of 86% of marine invertebrate species surveyed were active. Strong activity was detected in extracts from two bivalve species (Tridacna squamosa and Geloina coaxans) and three gastropod species (Tutufa rubeta, Pleuroploca trapezium and Tectus conus) with enzyme-treated rabbit, horse and human A, B, O erythrocytes. In a haemagglutination–inhibition test with various monosaccharides and glycoproteins, haemagglutination activities of two extracts from T. rubeta and P. trapezium had no affinity for any of the monosaccharides and glycoproteins tested, while activities of the extracts from T. squamosa and T. conus were strongly inhibited by porcine stomach mucin tested, suggesting the presence of lectins specific for O-glycans of these species. The activities of four marine invertebrate extracts were stable over a wide range ofpH and temperature. The haemagglutination activities of T. rubeta and P. trapezium extracts were independent of the presence of divalent cations, whereas the haemagglutination activity of extracts from T. squamosa and T. conus were slightly dependent on the presence of divalent cations. The results suggest that Vietnam marine invertebrates may be good sources of useful lectins for biochemical and biomedical applications