30 research outputs found

    Rehabilitation nach Hochdosis-Chemotherapie und allogener KMT (HSCT)

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    Region-Based Guaranteed Image Quality in JPEG2000

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    This paper describes a spatially variant method that optimises the compression rate within a given image dynamically depending on the application specific requirements and the actual image content. The concept utilises the JPEG2000 standard, however, a generalised region-of-interest (ROI) map is used in this paper together with a different post-compression rate distortion optimisation. The generalised ROI map comprises a multi-level priority scheme as well as continuously adjustable qualities for each individual region to reflect the application specific requirements for a particular image. The key point is that these pre-defined quality constraints are always met for each individual region, thus making the approach suitable for data with inherent reliability requirements. The implementation of the proposed system is transparent and concerns only the encoder side while any standard JPEG2000 decoder can be used for decompression. Results have shown that for the utilised imagery, i.e. satellite and medical images, compression rate improvements of up to 32% in comparison to the JPEG2000 compressor fulfilling the same quality needs are achievable

    Emergence of linezolid- and vancomycin-resistant Enterococcus faecium in a department for hematologic stem cell transplantation

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    Abstract Background Prevalence of vancomycin-resistant enterococci has increased in Germany. Here, we report the cluster of linezolid- and vancomycin-resistant Enterococcus faecium (LVRE) in a German department for hematologic stem cell transplantation (HSCT). Methods In this retrospective analysis we included all patients with LVRE in a university-based department for HSCT in 2014 and 2015. Patients chart reviews were used to investigate the epidemiology and clinical outcome. Available LVRE isolates underwent detailed microbiological characterization and genotyping by pulsed-field gel electrophoresis (PFGE). Results In total, 20 patients with LVRE were identified within the observed time period. All except two patients underwent allogeneic HSCT. Surveillance culture results from incoming patients and chart review revealed that 10 of 20 patients were colonized at hospital admission. Eight of 10 patients with in-hospital acquired LVRE had previous linezolid treatment. Analysis of spatio-temporal patterns showed no evidence for LVRE patient-to-patient or environment-to-patient transmission within the HSCT department. In five cases (25 %) LVRE bloodstream infection occurred. Nine LVRE isolates could be saved for characterization. Eight isolates carried vanA, one isolate vanB. PFGE analysis showed that four different LVRE clones were responsible for the cluster. One single genotype was present in six LVRE isolates whereupon the corresponding patients were all referred from the same hospital to the HSCT department. Conclusions This is the first report demonstrating the emergence of LVRE in a German HSCT department. (L)VRE screening at patients’ admission and appropriate infection control strategies were sufficient to prevent any transmission. Further studies in this predisposed patient collective are warranted
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