19 research outputs found
Restless legs syndrome: study of prevalence among medical school faculty members
- Author
- Aline Sponchiado Assoni
- Allen RP
- Andre Vicente Bigolin
- Aukerman MM
- Berger K
- Chaudhuri KR
- Chaudhuri KR
- Chokrovertry S
- Claudia Franzoi Fam
- Cristiane Mezzomo
- Culebras A.
- Ekbom KA
- Fábio Maraschin Haggstram
- Hening W
- Hoodes E
- Högl B
- Isabela Wasum dos Santos
- Johns MW
- Kripke DF
- Lavigne GJ
- Lee KA
- Manconi M
- Mariele Ribeiro Correa
- Montplaisir J
- Ohayon MM
- Phillips B
- Reynold CF
- Rothdach AJ
- Rutkove BR
- Sevim S
- Tatiana Linhares
- Trenkwalder C
- Ulfberg J
- Walters AS
- Weimerskirch PR
- Zucconi M
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
- A Abbott
- A Abou-Raya
- A Aljandali
- A Ambesi-Impiombato
- A Aydin
- A Balcerczyk
- A Besarab
- A Brzezinski
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- A Carrillo-Vico
- A Cavalli
- A Chattopadhyay
- A Chattopadhyay
- A Cherubini
- A Dey
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- A Donovan
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- A Gaeta
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- A Gopalakrishnan
- A Hald
- A Henney
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- A Kasztler
- A Kibel
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- A Kumral
- A Lass
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- A Lotery
- A Maggio
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- A Matsuzawa
- A Mitra
- A Monge
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- A Murakami
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- A Szewczyk
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- A Tedgui
- A Terman
- A Terman
- A Terman
- A Undas
- A Virdis
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- A Wagner
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- Z Cai
- Z Cheng
- Z Pei
- Z Serdar
- Z Tong
- Z Tong
- Z Yu
- Z Zhang
- ZD Liu
- ZD Liu
- ZE Karanjawala
- ZE Suntres
- ZI Cabantchik
- ZZ Chong
- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
Restless legs syndrome: overdiagnosed or underdiagnosed?
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Update on restless legs syndrome
- Author
- A Bauer
- A Oksenberg
- A Szentkirályi
- AS Walters
- AS Walters
- AV Salminen
- B Hogl
- B Hogl
- B Schormair
- C Prosperetti
- C Trenkwalder
- C Trenkwalder
- C Trenkwalder
- C Trenkwalder
- C Trenkwalder
- C Trenkwalder
- C Trenkwalder
- Claudia Trenkwalder
- CM Kaye
- D Garcia-Borreguero
- D Garcia-Borreguero
- DL Bliwise
- DL Picchietti
- EG Harrison
- F Provini
- Friederike Sixel-Döring
- H Benes
- HAF Brückmann
- J Schneider
- J Wang
- J Winkelmann
- J Winkelmann
- JR Connor
- JW Winkelman
- K Berger
- K Stiasny-Kolster
- KA Neve
- M Bayard
- M Hein
- M Manconi
- M-LFS-D Muntean
- Maria-Lucia Muntean
- Michael Bartl
- NB Nordlander
- P Gonzalez-Latapi
- PR Castillo
- RP Allen
- RP Allen
- RP Allen
- RP Allen
- S Clemens
- S Guo
- S Happe
- S Mackie
- S Meneely
- S Mizuno
- S Von Spiczak
- SM Patton
- T Nomura
- W Hening
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Management of hypertension by general practitioners: An Italian observational study
- Author
- A Crucitti
- A. Capuano
- A. Filippelli
- AH Jamali
- CK Yapp
- DM Lloyd-Jones
- DR Berlowitz
- E Erdmann
- E Espositi Degli
- F Avanzini
- F Rossi
- F. Mazzeo
- F. Rossi
- F. Russo
- FA McAlister
- FA McAlister
- G. Motola
- Guidelines Subcommittee
- H Olsen
- JJ Caro
- LM Prisant
- M Cranney
- M Monane
- M. R. Vitelli
- N Steel
- P Trenkwalder
- PR Edwards
- S Bonapace
- S. Rossi
- SS Mehta
- TO Morgan
- WC Cushman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Study on COgnition and Prognosis in the Elderly (SCOPE): Baseline Characteristics
- Author
- A. Castaigne
- A. Hofman
- A. Lobo
- A. Zanchetti
- B. Olofsson
- Barnes JM
- Barnes NM
- Belcher G
- Burt VL
- C. Farsang
- C. M. Bánki
- D. Elmfeldt
- D. Leys
- Dahlöf B
- E. Krisin
- Elmfeldt D
- Ernst RL
- F. M. Reischies
- Fagard RH
- G. Nordby
- G. Opolski
- H. Lithell
- Hansson L
- Holzgreve H
- I. Skoog
- Insua JT
- J-P. Degaute
- J. B. Rosenfeld
- J. Ferro
- J. Salerno
- J. Tilvis R
- K. Engedal
- Kannel WB
- L. Hansson
- L. Ruilope
- Lacourcière Y
- M. Breteler
- M. Correia
- M. Leeman
- M. Prince
- McInnes GT
- MRC Working Party
- O. F. W. James
- P. Trenkwalder
- P. W. de Leeuw
- SHEP Cooperative Research
- Skoog I
- Souetre EJ
- Tombaugh TN
- Trenkwalder PR
- V. Hachinski
- van den Bosch JH
- Vokonas PS
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Restless legs syndrome in Parkinson disease: Clinical characteristics, abnormal iron metabolism and altered neurotransmitters
- Author
- A Chaudhuri
- A Minguez-Castellanos
- AA Belaidi
- AJ Hughes
- C Pont-Sunyer
- C Trenkwalder
- CJ Earley
- DB Rye
- DY Kwon
- E Sofic
- E Svensson
- H Braak
- HH Andersen
- J Salazar
- J Sian-Hulsmann
- JC Moller
- JE Lee
- JH Jhoo
- JR Connor
- JR Connor
- K Bhalsing
- K Suzuki
- KD Alex
- M Bayard
- M Moccia
- M Politis
- N Pavese
- P Remy
- PR Krishnan
- RP Allen
- S Altamura
- S Arreguin
- S Clemens
- S Kedia
- S Mizuno
- S Thobois
- SA Eisenstein
- SM Fereshtehnejad
- W Zhang
- YS Oh
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Rotigotine transdermal patch and sleep in Parkinson’s disease: where are we now?
- Author
- A Ceballos-Baumann
- A Fasano
- A Meco Di
- A Rizos
- A Romigi
- A Ruffion
- AP Spira
- B Porter
- C Quiroz
- C Trenkwalder
- C Trenkwalder
- CA Kushida
- CJ Earley
- CL Comella
- D Berg
- D Scheller
- D Verbaan
- E Tandberg
- F Vallderiola
- G Calandra-Buonaura
- I Reuter
- IT French
- J Kassubek
- J Pagonabarraga
- JD Belluzzi
- JM Kim
- JP Elshoff
- JP Sieb
- JW Winkelman
- K Bhalsing
- K Ray Chaudhuri
- K Ray Chaudhuri
- K Stavitsky
- KR Chaudhuri
- KR Chaudhuri
- M Angelini
- M Canesi
- M Lazarus
- M Nedergaard
- M Pierantozzi
- MA Wilson
- MD Gjerstad
- ME Kalaitzakis
- MI Norlinah
- MK Scullin
- MP Broen
- MR Young Blood
- N Giladi
- N Sportiche
- NJ Diederich
- O Rascol
- P Jenner
- PJ Swart
- PR Krishnan
- R Bhidayasiri
- R Erro
- R Sakakibara
- R Stickgold
- RB Postuma
- RF Pfeiffer
- RM Rijsman
- RP Allen
- RP Allen
- RP Allen
- S Banks
- S Ferré
- S Happe
- S Isaacson
- S Marrinan
- T Thompson
- TH Johnston
- TM Rodrigues
- V Dhawan
- VP Calabrese
- Y Dauvilliers
- Y Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Shunts in normal-pressure hydrocephalus: do we place too many or too few?
- Author
- Arias E
- Bannister R
- Bech RA
- Bradley WG
- Brecknell JE
- Chang CC
- Cook SW
- de Jong DA
- Esmonde T
- Gallassi R
- Gold MR
- Graff-Radford NR
- Guidetti B
- Hakim CA
- Hertel F
- Hoglund M
- Hussey F
- Ishikawa M
- Klinge P
- Laws ER
- LeMay M
- Lobo A
- McCullough DC
- McHugh PR
- Meier U
- Meier U
- Meier U
- Mori K
- Morris JC
- Nakano H
- Ojemann RG
- Orr RK
- Pollay M
- Roque JA
- Salmon JH
- Schmitt J
- Shenkin HA
- Spanu G
- Spanu G
- Tans JT
- Trenkwalder C
- Udvarhelyi GB
- Vanneste JA
- Walchenbach R
- Williams MA
- Wolinsky JS
- Yock CA
- Publication venue
- 'Journal of Neurosurgery Publishing Group (JNSPG)'
- Publication date
- Field of study
Strategies for the Treatment of Restless Legs Syndrome
- Author
- A Parrow
- AL Ellenbogen
- AS Walters
- AS Walters
- AS Walters
- AS Walters
- B Frauscher
- B Högl
- B Högl
- B Phillips
- BJ Davis
- C Trenkwalder
- C Trenkwalder
- C Trenkwalder
- C Trenkwalder
- CA Kushida
- CA Kushida
- CH Adler
- CH Adler
- CJ Earley
- CJ Earley
- CJ Earley
- CM Dorsey
- D Garcia-Borreguero
- D Garcia-Borreguero
- D Garcia-Borreguero
- D Garcia-Borreguero
- DL Bliwise
- DL Drotts
- DM Raizen
- DO Lee
- EA Youssef
- EG Lutz
- EK Tan
- ER Sun
- F Gemignani
- F Gemignani
- FJ Sanz-Fuentenebro
- G Della Marca
- G Merlino
- G Merlino
- GA Mellick
- GJ Lavigne
- GJ Lavigne
- GL Gigli
- H Micozkadioglu
- HA Teive
- I Eisensehr
- J Kim
- J Montplaisir
- J Montplaisir
- J Montplaisir
- J Wang
- JA Molina
- JA Mountifield
- JD Goodman
- JJ Lee
- JW Winkelman
- JW Winkelman
- JW Winkelman
- K Berger
- K Berger
- K Berger
- K Ekbom
- K Stiasny-Kolster
- KA Ekbom
- KA Lee
- KE Innes
- KG Rottach
- KW Kim
- L Jimenez-Trevino
- LA Chiodo
- LK Brown
- LM Trotti
- M Abele
- M Auerbach
- M Bayard
- M Boentert
- M Koulu
- M Manconi
- M Manconi
- M Partinen
- M Polydefkis
- M Saletu
- M Sommer
- M Taşdemir
- M Tippmann-Peikert
- Mark J. Buchfuhrer
- MH Silber
- MJ Garvey
- MJ Krantz
- ML Thorp
- MM Aukerman
- MM Ohayon
- N Silver
- NB Nordlander
- NH Chen
- NP Pantaleo
- O Lundvall
- PR Krishnan
- R Allen
- R Allen
- R Hargrave
- R Hoque
- R Vetrugno
- RJ Salin-Pascual
- RJ Salín-Pascual
- RJ Uitti
- RK Bogan
- RK Bogan
- RP Allen
- RP Allen
- RP Allen
- RP Allen
- RP Allen
- S Akpinar
- S Happe
- S Happe
- S Sevim
- S Walker
- SB Rutkove
- ST O’Keeffe
- SW Kim
- T Kraus
- T Nomura
- T Roth
- T Terao
- TC Wetter
- TC Wetter
- W Oertel
- W Telstad
- WA Hening
- WA Hening
- WB Matthews
- WG Ondo
- WG Ondo
- WG Ondo
- WH Oertel
- WH Oertel
- WH Oertel
- WM Bahk
- X Gao
- Y Inoue
- YW Cho
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study