59 research outputs found
On the Origin of S0 Galaxies
I will review the basic properties of S0 galaxies in the local Universe in
relation to both elliptical and spiral galaxies, their neighbours on the Hubble
sequence, and also in relation to dwarf spheroidal (dSph) galaxies. This will
include colours, luminosities, spectral features, information about the age and
metallicity composition of their stellar populations and globular clusters,
about their ISM content, as well as kinematic signatures and their implications
for central black hole masses and past interaction events, and the number
ratios of S0s to other galaxy types in relation to environmental galaxy
density. I will point out some caveats as to their morphological discrimination
against other classes of galaxies, discuss the role of dust and the wavelength
dependence of bulge/disk light ratios. These effects are of importance for
investigations into the redshift evolution of S0 galaxies -- both as individual
objects and as a population. The various formation and transformation scenarios
for S0 and dSph galaxies will be presented and confronted with the available
observations.Comment: Invited Review, 18 pages, ``BARS 2004'' Conference, South Africa,
June 2004, eds.: K. C. Freeman, D. L. Block, I. Puerari, R. Groess, Kluwer,
in pres
Budesonide Foam Has a Favorable Safety Profile for Inducing Remission in Mild-to-Moderate Ulcerative Proctitis or Proctosigmoiditis
Utility of perinuclear anti-neutrophil cytoplasmic antibodies (pANCA), anti-saccharomyces cerevisiae (ASCA), and anti-pancreatic antibodies (APA) as serologic markers in a population based cohort of patients with Crohn's disease (CD) and ulcerative colitis (UC).
Evaluation of perinuclear anit-neutrophil cytoplasmic antibodies (pANCA), anti-saccharomyces cerevisiae (ASCA), and anti-pancreatic antibodies (APA) as serologic markers in a population based cohort of patients with Crohn's disease and ulcerative colitis
Evaluation of serologic disease markers in a population-based cohort of patients with ulcerative colitis and Crohn's disease.
BACKGROUND: The sensitivity of assays for antineutrophil cytoplasmic antibody (ANCA), anti-Saccharomyces cerevisiae antibody (ASCA), and antipancreatic antibody (PAB) in different laboratories is unknown. Likewise, the sensitivity and diagnostic usefulness of these assays in patients with inflammatory bowel disease (IBD) in the community is unknown. METHODS: An incidence cohort of 290 patients with IBD were offered participation in the study. Blood was obtained from 162 patients (56%) (83 with ulcerative colitis, 79 with Crohn's disease) who agreed to participate. ANCA was determined in five laboratories. ASCA in two laboratories, and PAB in one laboratory. RESULTS: In ulcerative colitis, the sensitivity of ANCA determined in five laboratories varied widely, ranging from 0-63%. In Crohn's disease, the sensitivity of ASCA determined in two laboratories did not vary significantly, ranging from 39-44%; and the sensitivity of PAB determined in one laboratory was 15%. The optimal diagnostic usefulness was obtained from one laboratory where the positive predictive values of a positive ANCA assay combined with a negative ASCA assay for ulcerative colitis, and a negative ANCA combined with a positive ASCA for Crohn's disease, were 75% and 86%, respectively. CONCLUSIONS: In patients with IBD, the sensitivity of ANCA varied widely in different laboratories, whereas the prevalence of ASCA was similar. The positive predictive values of the ANCA assay combined with the ASCA assay for ulcerative colitis and Crohn's disease are high enough to be clinically useful
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