9 research outputs found
A manganese porphyrin-based T1 contrast agent for cellular MR imaging of human embryonic stem cells
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Expression of steroid receptors in intact rat uterus, mammary gland, and liver treated with selective estrogen receptor modulators and conjugated equine estrogens
No full textThe effects of boric acid on sister chromatid exchanges and chromosome aberrations in cultured human lymphocytes
No full textThe aim of this study was to determine the possible genotoxic effects of boric acid (BA) (E284), which is used as an antimicrobial agent in food, by using sister chromatid exchange (SCEs) and chromosome aberration (CAs) tests in human peripheral lymphocytes. The human lymphocytes were treated with 400, 600, 800, and 1000 ÎĽg/mL concentrations of BA dissolved in dimethyl sulfoxide (DMSO), for 24Â h and 48Â h treatment periods. BA did not increase the SCEs for all the concentrations and treatment periods when compared to control and solvent control (DMSO). BA induced structural and total CAs at all the tested concentrations for 24 and 48Â h treatment periods. The induction of the total CAs was dose dependent for the 24Â h treatment period. However, BA did not cause numerical CAs. BA showed a cytotoxic effect by decreasing the replication index (RI) and mitotic index (MI). BA decreased the MI in a dose-dependent manner for the 24Â h treatment period
Urinary concentrations of phthalate metabolites in early pregnancy associated with clinical pregnancy loss in Chinese women
No full textLactational Exposure of Phthalate Impairs Insulin Signaling in the Cardiac Muscle of F1 Female Albino Rats
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