Synchronization in disordered Josephson junction arrays: Small-world connections and the Kuramoto model

We study synchronization in disordered arrays of Josephson junctions. In the first half of the paper, we consider the relation between the coupled resistively- and capacitively shunted junction (RCSJ) equations for such arrays and effective phase models of the Winfree type. We describe a multiple-time scale analysis of the RCSJ equations for a ladder array of junctions \textit{with non-negligible capacitance} in which we arrive at a second order phase model that captures well the synchronization physics of the RCSJ equations for that geometry. In the second half of the paper, motivated by recent work on small world networks, we study the effect on synchronization of random, long-range connections between pairs of junctions. We consider the effects of such shortcuts on ladder arrays, finding that the shortcuts make it easier for the array of junctions in the nonzero voltage state to synchronize. In 2D arrays we find that the additional shortcut junctions are only marginally effective at inducing synchronization of the active junctions. The differences in the effects of shortcut junctions in 1D and 2D can be partly understood in terms of an effective phase model.Comment: 31 pages, 21 figure

Ziv-Zakai Error Bounds for Quantum Parameter Estimation

I propose quantum versions of the Ziv-Zakai bounds as alternatives to the widely used quantum Cram\'er-Rao bounds for quantum parameter estimation. From a simple form of the proposed bounds, I derive both a "Heisenberg" error limit that scales with the average energy and a limit similar to the quantum Cram\'er-Rao bound that scales with the energy variance. These results are further illustrated by applying the bound to a few examples of optical phase estimation, which show that a quantum Ziv-Zakai bound can be much higher and thus tighter than a quantum Cram\'er-Rao bound for states with highly non-Gaussian photon-number statistics in certain regimes and also stay close to the latter where the latter is expected to be tight.Comment: v1: preliminary result, 3 pages; v2: major update, 4 pages + supplementary calculations, v3: another major update, added proof of "Heisenberg" limit, v4: accepted by PR

Estimating the spectrum of a density matrix with LOCC

The problem of estimating the spectrum of a density matrix is considered. Other problems, such as bipartite pure state entanglement, can be reduced to spectrum estimation. A local operations and classical communication (LOCC) measurement strategy is shown which is asymptotically optimal. This means that, for a very large number of copies, it becomes unnecessary to perform collective measurements which should be more difficult to implement in practice.Comment: 12 pages, uses iopart.cls and iopart10.clo. Improved version. v3: Reference updated, added journal referenc

Instabilities in Josephson Ladders with Current Induced Magnetic Fields

We report on a theoretical analysis, consisting of both numerical and analytic work, of the stability of synchronization of a ladder array of Josephson junctions under the influence of current induced magnetic fields. Surprisingly, we find that as the ratio of the mutual to self inductance of the cells of the array is increased a region of unstable behavior occurs followed by reentrant stable synchronization. Analytic work tells us that in order to understand fully the cause of the observed instabilities the behavior of the vertical junctions, sometimes ignored in analytic analyses of ladder arrays, must be taken into account.Comment: RevTeX, 4 pages, 3 figure

Does nonlinear metrology offer improved resolution? Answers from quantum information theory

A number of authors have suggested that nonlinear interactions can enhance resolution of phase shifts beyond the usual Heisenberg scaling of 1/n, where n is a measure of resources such as the number of subsystems of the probe state or the mean photon number of the probe state. These suggestions are based on calculations of `local precision' for particular nonlinear schemes. However, we show that there is no simple connection between the local precision and the average estimation error for these schemes, leading to a scaling puzzle. This puzzle is partially resolved by a careful analysis of iterative implementations of the suggested nonlinear schemes. However, it is shown that the suggested nonlinear schemes are still limited to an exponential scaling in \sqrt{n}. (This scaling may be compared to the exponential scaling in n which is achievable if multiple passes are allowed, even for linear schemes.) The question of whether nonlinear schemes may have a scaling advantage in the presence of loss is left open. Our results are based on a new bound for average estimation error that depends on (i) an entropic measure of the degree to which the probe state can encode a reference phase value, called the G-asymmetry, and (ii) any prior information about the phase shift. This bound is asymptotically stronger than bounds based on the variance of the phase shift generator. The G-asymmetry is also shown to directly bound the average information gained per estimate. Our results hold for any prior distribution of the shift parameter, and generalise to estimates of any shift generated by an operator with discrete eigenvalues.Comment: 8 page

Quantum theory of optical temporal phase and instantaneous frequency. II. Continuous time limit and state-variable approach to phase-locked loop design

We consider the continuous-time version of our recently proposed quantum theory of optical temporal phase and instantaneous frequency [Tsang, Shapiro, and Lloyd, Phys. Rev. A 78, 053820 (2008)]. Using a state-variable approach to estimation, we design homodyne phase-locked loops that can measure the temporal phase with quantum-limited accuracy. We show that post-processing can further improve the estimation performance, if delay is allowed in the estimation. We also investigate the fundamental uncertainties in the simultaneous estimation of harmonic-oscillator position and momentum via continuous optical phase measurements from the classical estimation theory perspective. In the case of delayed estimation, we find that the inferred uncertainty product can drop below that allowed by the Heisenberg uncertainty relation. Although this result seems counter-intuitive, we argue that it does not violate any basic principle of quantum mechanics.Comment: 11 pages, 6 figures, v2: accepted by PR

Statistical Communication Theory

Contains reports on four research projects

Statistical Communication Theory

Contains report listing completed research projects.Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 36-039-AMC-03200(E)National Aeronautics and Space Administration (Grant NsG-496)National Science Foundation (Grant GK-835)National Aeronautics and Space Administration Grant (NsG-334

Statistical Communication Theory

Contains reports on three research projects.National Science Foundation (Grant GP-2495)National Aeronautics and Space Administration (Grant NsG-496)National Institutes of Health (Grant MH-04737-04

Trained immunity or tolerance : opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors

Article Accepted Date: 29 January 2014. ACKNOWLEDGMENTS D.C.I. received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement HEALTH-2010-260338 (“Fungi in the setting of inflammation, allergy and autoimmune diseases: translating basic science into clinical practices” [ALLFUN]) (awarded to M.G.N.). M.G.N. and J.Q. were supported by a Vici grant of the Netherlands Organization of Scientific Research (awarded to M.G.N.). This work was supported, in part, by National Institutes of Health grant GM53522 to D.L.W. N.A.R.G. was supported by the Wellcome Trust.Peer reviewedPublisher PD