FATTY ACID COMPOSITION AND ANTIOXIDANT ACTIVITY OF CAMELLIA NINHII SEED OIL COLLECTED IN LAM DONG PROVINCE

The seed oil of Camellia ninhii was studied for the first time on its fatty acid composition by gas chromatography-mass spectrometry (GC-MS) and antioxidant activity by the DPPH method. The results show that unsaturated fatty acids account for the largest amount, especially oleic acid with 45.43% of the total sample analyzed. In addition, other fatty acids, palmitic, linoleic, pentadecanoic, and two aromatic acids, benzoic and cinnamic, were present. The sample of C. ninhii seed oil exhibited mild antioxidant activity against DPPH free radicals with IC50 = 0.94 mg/mL

Assessing the efficacy and safety of magnesium sulfate for management of autonomic nervous system dysregulation in Vietnamese children with severe hand foot and mouth disease.

BACKGROUND: Brainstem encephalitis is a serious complication of hand foot and mouth disease (HFMD) in children. Autonomic nervous system (ANS) dysregulation and hypertension may occur, sometimes progressing to cardiopulmonary failure and death. Vietnamese national guidelines recommend use of milrinone if ANS dysregulation with Stage 2 hypertension develops. We wished to investigate whether magnesium sulfate (MgSO4) improved outcomes in children with HFMD if used earlier in the evolution of the ANS dysregulation (Stage 1 hypertension). METHODS: During a regional epidemic we conducted a randomized, double-blind, placebo-controlled trial of MgSO4 in children with HFMD, ANS dysregulation and Stage 1 hypertension, at the Hospital for Tropical Diseases in Ho Chi Minh city. Study participants received an infusion of MgSO4 or matched placebo for 72 h. We also reviewed data from non-trial HFMD patients in whom milrinone failed to control hypertension, some of whom received MgSO4 as second line therapy. The primary outcome for both analyses was a composite of disease progression within 72 h - addition of milrinone (trial participants only), need for ventilation, shock, or death. RESULTS: Between June 2014 and September 2016, 14 and 12 participants received MgSO4 or placebo respectively, before the trial was stopped due to futility. Among 45 non-trial cases with poorly controlled hypertension despite high-dose milrinone, 33 received MgSO4 while 12 did not. There were no statistically significant differences in the composite outcome between the MgSO4 and the placebo/control groups in either study (adjusted relative risk (95%CI) of [6/14 (43%) vs. 6/12 (50%)], 0.84 (0.37, 1.92), p = 0.682 in the trial and [1/33 (3%) vs. 2/12 (17%)], 0.16 (0.01, 1.79), p = 0.132 in the observational cohort). The incidence of adverse events was similar between the groups. Potentially toxic magnesium levels occurred very rarely with the infusion regime used. CONCLUSION: Although we could not demonstrate efficacy in these studies, there were no safety signals associated with use of 30-50 mg/kg/hr. MgSO4 in severe HFMD. Intermittent outbreaks of HFMD are likely to continue across the region, and an adequately powered trial is still needed to evaluate use of MgSO4 in controlling hypertension in severe HFMD, potentially involving a higher dose regimen. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01940250 (Registered 22 AUG 2013). Trial sponsor: University of Oxford

Prevalence of resistance to second-line tuberculosis drug among multidrug-resistant tuberculosis patients in Viet Nam, 2011

Introduction: Extensively drug-resistant tuberculosis (XDR-TB) represents an emerging public health problem worldwide. According to the World Health Organization, an estimated 9.7% of multidrug-resistant TB (MDR-TB) cases are defined as XDR-TB globally. The objective of this study was to determine the prevalence of drug resistance to second-line TB drugs among MDR-TB cases detected in the Fourth National Anti-Tuberculosis Drug Resistance Survey in Viet Nam. Methods: Eighty clusters of TB cases were selected using a probability-proportion-to-size approach. To identify MDR-TB cases, drug susceptibility testing (DST) was performed for the four major first-line TB drugs. DST of second-line drugs (ofloxacin, amikacin, kanamycin, capreomycin) was performed on isolates from MDR-TB cases to identify pre-XDR and XDR cases. Results: A total of 1629 smear-positive TB cases were eligible for culture and DST. Of those, DST results for first-line drugs were available for 1312 cases, and 91 (6.9%) had MDR-TB. Second-line DST results were available for 84 of these cases. Of those, 15 cases (17.9%) had ofloxacin resistance and 6.0% were resistant to kanamycin and capreomycin. Five MDR-TB cases (6.0%) met the criteria of XDR-TB. Conclusion: This survey provides the first estimates of the proportion of XDR-TB among MDR-TB cases in Viet Nam and provides important information for local policies regarding second-line DST. Local policies and programmes that are geared towards TB prevention, early diagnosis and treatment with effective regimens are of high importance

Adopting the Health Belief Model and Social Cognitive Theory Framework to Explore Factors Impacting STIs Prevention Behaviors Among Youth: A Case Study in Vietnam

Sexually transmitted infections (STIs) are an important health concern in Vietnam, with a consistently increasing prevalence, particularly in youths. These infections have significant consequences for personal health, longevity, and the welfare of society. Preventive measures against STIs among Vietnamese young have become common, bringing noteworthy challenges despite the importance of the circumstances. The authors evaluate the actual preventive measures used by this particular population for STIs. Our research explores the influences on STI prevention by combining the Social Cognitive Theory (SCT) with the Health Belief Model (HBM). We collected data from 835 respondents across various areas of Vietnam via SPSS 26.0 and SmartPLS 4.0 software. The results highlighted the key factors that influence STIs prevention and provided recommendations to enhance these preventive actions. The goal of this research is to reduce STIs rates and enhance sexual and reproductive health in young adults to ensure a better future. Keywords: STIs prevention behaviors, the Health Belief Model, Social Cognitive Theory, Youth in Vietnam DOI: 10.7176/JESD/15-3-01 Publication date:March 31st 202

Comorbidities of diabetes and hypertension in Vietnam: current burden, trends over time, and correlated factors

Abstract Background Vietnam conducted the national Noncommunicable Disease Risk-Factor Surveillance (STEPs) surveys in the years 2010, 2015, and 2021. This study aims to use STEPs data to assess the burden of comorbidity between diabetes and hypertension, analyze trends over time, and identify factors associated with this comorbidity. Methods The study extracted data for the population aged 25–64 years old from three STEPs surveys. Survey weight was used for all estimations of prevalence and 95% CI. Correlated factors with comorbidity were examined by a multivariate logistics model. Results The prevalence of comorbidity in 2021 was about 3.92% among Vietnamese people aged 25–64. In the last 10 years, this prevalence has increased more than 8 times (from 0.44% to 3.92%). Sub-populations demonstrating the most significant changes included the male population, people living in urban areas, and older people. Significant factors correlated with comorbidity included demographic factors, body mass index (BMI), and clustering of 4 noncommunicable diseases (NCDs) behavioral risk factors (OR = 3.48, p < 0.05). Conclusion The high comorbidity between hypertension and diabetes underscores the imperative for integrated treatment and management approaches in Vietnam. Coordinated care is essential for addressing the complex interplay between these two prevalent conditions

Purification and Characterization of High Purity Nano Zirconia by Liquid-Liquid Extraction Using D2EHPA/p-Xylenes

In this paper, Zr(IV) nitrate solution decomposed from Viet Nam zircon concentrate was the source of zirconium extraction by liquid-liquid extraction (L.L.E). The FT-IR and UV-Vis spectra confirmed the extraction of Zr(IV) by D2EHPA/p-xylenes. There were four stages for the purification of impurities from the Zr matrix. First, the extraction of elements in 3.0 M HNO3 by 50% D2EHPA/p-xylenes was conducted. Second, two scrubbing cycles of impurities using 6.0 M HNO3, 76.5% of the total amount of Zr(IV) were retained in the organic phase, and 23.5% remained in the aqueous phase. Third, the stripping of a macro amount of zirconium from loaded D2EHPA has been effectively carried out using 1.5 M H2SO4 with a stripping efficiency of 99.6%. Fourth, concentrated ammonia was added to the solution Zr(IV) after stripping extraction to form precipitate for calcination at 550 &deg;C for the final products. The refined products were characterized by X-ray diffraction, scanning electron microscopy (SEM), transmission electron microscopy (TEM), EDS, XRF, and diffuse reflectance spectroscopy. The ZrO2 has high purity, is nanospherical, and has a uniform sphere-like morphology with small grain size of less than 30 nm and a bandgap value of about 3.30 eV

Ce3+/Ce4+-Doped ZrO2/CuO Nanocomposite for Enhanced Photocatalytic Degradation of Methylene Blue under Visible Light

In recent years, photocatalysis has been used as an environmentally friendly method for the degradation of organic pigments in water. In this study, Ce3+/Ce4+-doped ZrO2/CuO as a mixed semiconductor oxide was successfully prepared by a one-step hydrothermal method. The Ce3+/Ce4+-doped ZrO2/CuO has shown high degradation efficiency of methylene blue (MB), and the maximum degradation percentage was observed to be 94.5% at 180 min under irradiation visible light. The photocatalytic activity increases significantly by doping Ce3+/Ce4+ in ZrO2/CuO for MB degradation. Ce3+/Ce4+ doping is shown to reduce the (e-/h+) recombination rate and improve the charge transfer, leading to enhanced photocatalytic activity of materials. The materials were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), FTIR, EDS, BET and diffuse reflectance spectroscopy (DRS)

Proceedings of the 4th Conference on Language Teaching and Learning

This conference proceedings contains articles on the various research ideas of the academic community and practitioners presented at the 4th Conference on Language Teaching and Learning (LTAL-2022). LTAL2022 was organized by the Ho Chi Minh City University of Food Industry, Vietnam on June 19-20, 2022. Conference Title: 4th Conference on Language Teaching and LearningConference Acronym: LTAL-2022Conference Date: 19-20 June 2022Conference Location: VietnamConference Organizers: Ho Chi Minh City University of Food Industry, Vietnam