63 research outputs found

    AN EVALUATION ON THE REFLECTIONS OF SCHOOL GARDENS ON EDUCATION

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    This study aims to determine the physical conditions, cleanliness and order of the school gardens, the conditions of the garden walls and the security measures taken regarding the gardens, and to reveal the reflections of these features on education. This study, which also tries to reveal the satisfaction levels of students, parents, teachers and school administrators regarding school gardens, is qualitative research in the survey model. Research data were collected by natural/unstructured observation and semi-structured interview techniques. Content analysis technique was used in the analysis of the data. This study was conducted in six official primary schools at lower, middle and upper socio-economic levels, and interviews were conducted with 101 students, 35 parents, 22 teachers and 6 administrators in these schools. In the research, it was determined that the school gardens do not have the features to increase the physical activity of the students, there are insufficient and unplanned applications in the gardens, and the gardens do not contribute to educational activities. In addition, it has been determined that students, parents, teachers and administrators are not satisfied with the physical conditions, cleanliness and order of the school gardens, the condition of the garden walls and security measures.  Article visualizations

    Gastroözofageal reflüsü olan hastaların yaşam kalitesinin değerlendirilmesi

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    06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması, Düzenlenmesi ve Erişime Açılmasına İlişkin Yönerge” gereğince tam metin erişime açılmıştır.GİRİŞ VE AMAÇ: Çalışma, Gastroözofageal Reflü Hastalığı Yaşam Kalitesi ölçeğinin (GERD-QOL) Türkçe geçerlik-güvenirliğini yapmak, hastaların yaşam kalitelerini değerlendirmek ve etkileyen faktörleri belirlemek amacıyla yapıldı. GEREÇ VE YÖNTEM: Metadolojik ve tanımlayıcı özellikte planlanan çalışmanın örneklemini Temmuz 2017- Ekim 2017 tarihleri arasında bir üniversite hastanesi gastroenteroloji polikliniğine başvuran GÖRH tanısı almış 161 hasta oluşturdu. Sosyodemografik özellikleri içeren hasta bilgi formu, Gastroözofageal Reflü Hastalığı Yaşam Kalitesi Ölçeği (GÖRH-YKÖ), SF-36 Yaşam Kalitesi Ölçeği, Gastrointestinal Semptom Anketi kullanılarak toplanılan verilerin analizi, bilgisayar ortamında geçerlik ve güvenirlik analizleri, yüzdelik, ortalama, bağımsız t testi, ANOVA, Pearson's korelasyon testleri kullanılarak yapıldı. BULGULAR: GÖRH-YKÖ'nin dil geçerliği, kapsam geçerliliği (KGİ>0,80), Cronbach's Alpha Güvenirlik Katsayısı (α=0,885) ve doğrulayıcı faktör analizi ile yapılan geçerlik ve güvenirlik çalışması sonucuna göre geçerli ve güvenilir bir ölçek olduğu saptandı. Hastaların GÖRH-YKÖ'den aldıkları ortalama puanın 46,58±25,56, SF 36 fiziksel ana boyut puan ortalamalasının 54,24±22,61 ve Mental ana boyut puan ortalamalasının 50,42±21,38 olduğu görüldü. İleri yaş, düşük eğitim seviyesi, gelir düzeyinin düşük olması, bekar olma, yüksek BKİ, yemek yeme hızı, uykudan kalkıp yemek yeme, doktor tarafından tanı koyulan başka bir hastalık varlığı ve düzenli ilaç kullanmanın GÖR hastalarının yaşam kalitesini olumsuz etkileyen faktörler olduğu belirlendi. Sigara içme, alkol kullanma, öğün atlama ile yaşam kalitesi arasında anlamlı fark bulunmadı. SONUÇ: GÖRH-YKÖ'nin, GÖRH teşhisi koyulan bireylerin yaşam kalitesini ölçebilecek geçerli ve güvenilir bir ölçek olduğu belirlendi. GÖRH'nin bireylerin yaşam kalitesini olumsuz etkilediği bulundu. Anahtar Kelimeler: Gastroözofageaal reflü, Geçerlik, Güvenirlik, Hasta, Ölçek, Yaşam Kalitesi.Evaluatıon Of Quality Of Life İn Patients With Gastroesophageal Reflux INTRODUCTION AND AIM: The aim of the present study was to perform the validity-reliability of the Turkish version of the Gastroesophageal Reflux Disease Quality of Life (GERD-QOL) scale, to assess the quality of life of the patients, and to determine the influencing factors. MATERIALS AND METHODS: 161 GERD patients who applied to the gastroenterology outpatient department of a university hospital between July 2017 and October 2017 constitute the sample of this study planned methodologically and with the descriptive characteristic. The data were collected by using the Patient Information Forms covering the socio-demographic characteristics, Quality of Life Scale for Gastroesophageal Reflux Disease (GERD-QOL), SF-36 Quality of Life Scale, and Gastrointestinal Symptom Questionnaire. The analysis of these data was made by using validity and reliability analysis, the percentage, the mean, independent samples t-test, ANOVA, and Pearson correlation analysis in the computer environment. RESULTS: GERD-QOL scale was determined to be valid and reliable as the result of the study made for the validity and reliability with the language validity, content validity (CV> 0.80), Cronbach's Alpha reliability coefficient (α = 0.885), and confirmatory factor analysis. It was observed that the mean score of the patients taken from the GERD-QOL was 46.58 ± 25.56; the mean score of the SF 36 physical main dimension was 54.24 ± 22.61; and the mean score of the mental main dimension was 50.42 ± 21.38. It was found that advanced age, low education level low-income level, single life, high BMI (body mass index), eating rate, sleep eating, the presence of another disease diagnosed by the doctor, and using regular medication were the factors that affect the quality of life of GERD patients. There was no statistically significant difference between the quality of life and smoking, alcohol use, skipping meals. CONCLUSION: It was determined that GERD-QOL was a valid and reliable scale that could measure the quality of life of the GERD individuals. It was found that GERD adversely affected the quality of life of individuals. Keywords: Gastroesophageal reflux, Validity, Reliability, Patient, Scale, Quality of Life

    Uzun dönemli elektronik iletişimli takipin implantlı kemik/eklem enfeksiyonunu belirleme rolünün araştırılması

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    06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması, Düzenlenmesi ve Erişime Açılmasına İlişkin Yönerge” gereğince tam metin erişime açılmıştır.GİRİŞ VE AMAÇ: Çalışma kemik/eklem implantı takılı hastalara taburculuk sonrası 90 gün boyunca iletişim kurularak cerrahi alan enfeksiyonlarını tespit etmede telefon ile iletişimin etkinliğini belirlemek amacıyla yapıldı. GEREÇ VE YÖNTEM: Prospektif, randomize kontrollü ve tanımlayıcı özellikte planlanan çalışmanın örneklemini Şubat 2014-Ekim 2014 tarihleri arasında bir üniversite hastanesinde beyin cerrahi ve ortopedi kliniklerinde implant takılı 380 hasta oluşturdu. Çalışma, telefonla takip ve standart takip olmak üzere randomize iki gruba ayrıldı. Telefonla takip grubu taburculuğu takiben 30-60-90 günlerinde telefon ile aranarak CDC kriterlerine göre cerrahi alan enfeksiyon (CAE) belirtileri sorgulandı. Standart takip grubundaki hastalar hastane otomasyon sisteminden taranıp taburculuğunu takiben 90 gün içerisinde hastaneye başvuruları incelendi. Her iki çalışma grubunda CAE belirtileri karşılaştırıldı ve enfeksiyon hızları belirlendi. Verilerin analizi, bilgisayar ortamında, yüzdelik, ortalama, bağımsız t testi, ki kare testi kullanılarak yapıldı. BULGULAR: Hastaların yaş ortalaması 57,30±14,287, hastanede yatış süresi 4,51±022 idi. Hastaların %29,5'i ASA sınıflamasında 1 puan, % 40,8'i 2 puan, %29,7'si 3 puan aldı. Telefonla takip grubunda cerrahi alan enfeksiyonu oranı %5,2, standart takip grubunda %4,3 bulundu. Telefon ile takip ve standart takip grupları arasında enfeksiyon oranlarında anlamlı bir farklılık bulunmadı (p>0,05). Enfeksiyonlu ve enfeksiyonsuz eklem replasmanı öyküsü risk faktörü olarak belirlendi. Çalışmada 380 hastanın 18'inde CAE (%4,73) tespit edildi. SONUÇ: Kemik/eklem implantı takılı hastalara taburculuk sonrası telefon ile takip etmenin cerrahi alan enfeksiyonlarını erkenden tespit etmediği bulundu. Anahtar Kelimeler: Cerrahi alan enfeksiyonu, Hastane enfeksiyonu, İmplant, Protez eklem enfeksiyonu, Telefon ile takip.INTRODUCTION AND AİM: The study was carried out to determine the efficacy of communication over telephone in determining surgical site infections by communicating with patients with bone/joint implants for 90 days following their discharge. MATERIALS AND METHOD: The study was planned to be a prospective, randomized controlled and descriptive research, and the sample of the study consisted of 380 patients who were implanted in neurosurgery and orthopedics clinics in a university hospital between February 2014 and October 2014. The study was divided into two randomized groups as follow-up with telephone group and standard follow-up group. The telephone follow-up group was called by telephone on 30, 60 and 90 days after the patients' discharge and the symptoms of surgical site infection (SSI) were questioned according to the CDC criteria. Patients in the standard follow-up group were monitored from the hospital automation system and their admittance to hospital within 90 days following their discharge was examined. SSI symptoms were compared between both groups and the infection rates were determined. The data were analyzed using computer software by percentage, mean, independent t test and chi square tests. RESULTS: The mean age of the patients was 57.30 ± 14.287 and the mean hospitalization duration was 4.51 ± 022. According to the ASA classification, 29.5% of the patients scored 1 point while 40.8% scored 2 points and 29.7% scored 3 points. Surgical site infection rate was 5.2% in the follow-up with telephone group while it was 4.3% in the standard follow-up group. There was no significant difference in infection rates between the follow-up with telephone group and standard follow-up group (p> 0.05). The history of joint replacement with and without infection was defined as the risk factor. SSI detected in 18 of the 380 patients (4.73%) in the study. CONCLUSION: It was found that follow-up with telephone was not effective in early determination of surgical site infections in patients with bone/joint implants. Keywords: Surgical site infection, Hospital infection, Implant, Prosthetic joint infection, Follow-up with telephone

    Microdevices for Continuous Sized Based Sorting by AC Dielectrophoresis

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    This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.In this project, various microfluidic devices are designed for microparticles and cells separation. The dominant regions of dielectrophoresis among other AC Electrokinetic transport mechanisms are predicted. Flow behaviors of particles for each design parameter are modeled and simulated using COMSOL Multiphysics 4.3a software. Lab-on-a-chip devices having a Ti interdigitated electrode layer on a glass substrate and a PDMS microchannel are fabricated to investigate the most effective design solution for separating particles based on their sizes. Polystyrene particles with different diameters of 3.2 μm and 9.8 μm are used in our experiments and experiments with circulating tumor cells (CTCs) are in progress

    Studying dynamic stress effects on the behaviour of THP-1 cells by microfluidic channels

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    Atherosclerosis is a long-term disease process of the vascular system that is characterized by the formation of atherosclerotic plaques, which are inflammatory regions on medium and large-sized arteries. There are many factors contributing to plaque formation, such as changes in shear stress levels, rupture of endothelial cells, accumulation of lipids, and recruitment of leukocytes. Shear stress is one of the main factors that regulates the homeostasis of the circulatory system; therefore, sudden and chronic changes in shear stress may cause severe pathological conditions. In this study, microfluidic channels with cavitations were designed to mimic the shape of the atherosclerotic blood vessel, where the shear stress and pressure difference depend on design of the microchannels. Changes in the inflammatory-related molecules ICAM-1 and IL-8 were investigated in THP-1 cells in response to applied shear stresses in an continuous cycling system through microfluidic channels with periodic cavitations. ICAM-1 mRNA expression and IL-8 release were analyzed by qRT-PCR and ELISA, respectively. Additionally, the adhesion behavior of sheared THP-1 cells to endothelial cells was examined by fluorescence microscopy. The results showed that 15 Pa shear stress significantly increases expression of ICAM-1 gene and IL-8 release in THP-1 cells, whereas it decreases the adhesion between THP-1 cells and endothelial cells

    Türk Biyokimya Dergisi

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    Characterization of polyphenol oxidase during three ripening stages of an eggplant (Solanum melongena L.) fruit: a local type in northeast Anatolia [Patlıcan (Solanum melongena L.) meyvesinin polifenol oksidazının üç olgunlaşma safhası boyunca karakterizasyonu: Doğu Anadolu' da yerel bir tip] ABSTRACT Objective: A relatively new local type of eggplant, Solanum melongena L. 'Kadife' is widely consumed in Turkey because of its economic availability and good nutritional qualities. However, the high polyphenol content of eggplant renders it susceptible to unattractive oxidative browning catalyzed by polyphenol oxides (PPOs). Therefore, the main aim of this study was to characterize PPO in this eggplant cultivar at three stages of its development. Methods: In this study, we determined substrate specificity, optimum pH and temperature, and optimum substrate concentration of the partial purified eggplant fruits PPO during ripening. Results: L-DOPA was proved to be the preferred PPO substrate in all three stages of ripening. Optimum activity was observed at pH 7.0 for PPO in extracts of ripening and overly-ripe eggplant, while activity in extracts of immature eggplant exhibited a broad pH optimum between, pH 5.0 and 7.0. In general, at all ripening stages, PPO was most active at 30°C and was most sensitive to inhibition by sodium metabisulphite and ascorbic acid. The metal ions (Hg ÖZET Amaç: Kısmen yeni bir yerel tip patlıcan çeşidi Solanum melongena L. 'Kadife', ekonomik uygunluğu ve iyi besin kalitesinden dolayı Türkiye'de yaygın olarak tüketilir. Bununla birlikte, patlıcanın yüksek polifenol içeriği, bu meyveyi polifenol oksidaz (PFO) tarafından katalizlenen istenmeyen oksidatif esmerleşmeye karşı duyarlı kılar. Dolayısıyla, bu çalışmanın temel amacı, gelişiminin üç safhasında bu patlıcan kültivarındaki PFO'yu karakterize etmektir. Metod: Bu çalışmada, olgunlaşma boyunca patlıcan meyvelerinden elde edilen kısmi saflaştı-rılmış PFO'nun substrat özgünlüğünü, optimum pH ve sıcaklığını, ve optimum substrat konsantrasyonunu belirledik. Bulgular: Olgunlaşmanın her üç safhasında, L-DOPA'nın tercih edilen PFO substratı olduğu ortaya konuldu. Olgunlaşmamış patlıcan özütlerinde optimum pH 5.0 ile 7.0 arasında geniş bir aktivite gösterirken olgun ve aşırı olgun patlıcan özütlerindeki PFO aktivitesi için optimum pH'nın 7.0 olduğu gözlendi. Genel olarak, tüm olgunlaşma safhalarında, PFO, 30°C'de en aktiftir ve inhibitör olarak sodyum metabisülfit ve askorbik aside oldukça duyarlıdır. Materials and Methods Plant material The seeds belonging to the eggplant (Solanum melongena) were obtained from local growers, but they have not certificated yet
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