168 research outputs found

    The inclusion of students with autistic spectrum disorders associated with Asperger's Syndrome

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    La diversitat forma part de la realitat de la societat i, l’alumne amb Trastorn d’Espectre Autista derivat de Síndrome d’Asperger presenta una necessitat que nosaltres com a docents, familiars o ciutadans tenim l’obligació de satisfer. Així doncs, hauríem d’actuar seguint el model d’educació inclusiva i sempre pensant que la prioritat és aconseguir un desenvolupament integral de l’alumnat. L’objectiu principal del treball és establir un primer contacte amb alguns experts i centres educatius i esbrinar així, si l’enfocament educatiu que se li dóna al Trastorn d’Espectre Autista és propi de centres inclusius.The diversity is part of the reality of our society and students with Autism Spectrum Disorder (ASD) derived from Asperger Syndrome (AS) presents a necessity that we (teachers, parents or citizens) have to fulfill. So, we should act on an inclusive education model because the priority is to develop holistically students. The main objective of this paper is to establish a first contact with some experts and schools and find out, if th eeducationa lfocus (attention and intervention) that is given to autistic spectrum disorder (ASD) derived from Asperger Syndrome (AS) is own inclusive school communities

    Effect of minor Co additions on the crystallization and magnetic properties of Fe(Co)NbBCu alloys

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    The effect of partial replacement of Fe by Co (up to 8 %) on thermal stability, structure and magnetic properties of FeNbBCu alloys has been explored in this paper. The results indicate that Co reduces the stability against crystallization of the amorphous alloy and stabilizes the nanocrystalline phase prior to the further precipitation of metastable boride phases. Transmission Mössbauer spectroscopy reveals differences in the hyperfine interactions between the alloys: Co raises the mean hyperfine field of the amorphous state and differences in the nanocrystalline bcc-Fe(Co) environments between the alloys occur depending on the amount of Co near-neighbours in the bcc-Fe structure. The addition of Co has also a notable effect on the magnetic properties of both amorphous and nanocrystalline alloys increasing the Curie temperature, which shows a linear dependence with the Co composition, and the saturation polarization.Peer ReviewedPostprint (author’s final draft

    Distance dependent contribution of ants to pollination but not defense in a dioecious, ambophilous gymnosperm

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    Dioecious plants are obligate outcrossers with separate male and female individuals, which can result in decreased seed set with increasing distance between the sexes. Wind pollination is a common correlate of dioecy, yet combined wind and insect pollination (ambophily) could be advantageous in compensating for decreased pollen flow to isolated females. Dioecious, ambophilous gymnosperms Ephedra (Gnetales) secrete pollination drops (PDs) in female cones that capture airborne pollen and attract ants that feed on them. Plant sugary secretions commonly reward ants in exchange for indirect plant defense against herbivores, and more rarely for pollination. We conducted field experiments to investigate whether ants are pollinators and/or plant defenders of South American Ephedra triandra, and whether their contribution to seed set and seed cone protection varies with distance between female and male plants. We quantified pollen flow in the wind and assessed the effectiveness of ants as pollinators by investigating their relative contribution to seed set, and their visitation rate in female plants at increasing distance from the nearest male. Ants accounted for most insect visits to female cones of E. triandra, where they consumed PDs, and pollen load was larger on bigger ants without reduction in pollen viability. While wind pollination was the main contributor to seed set overall, the relative contribution of ants was distance dependent. Ant contribution to seed set was not significant at shorter distances, yet at the farthest distance from the nearest male (23 m), where 20 times less pollen reached females, ants enhanced seed set by 30% compared to plants depending solely on wind pollination. We found no evidence that ants contribute to plant defense by preventing seed cone damage. Our results suggest that, despite their short-range movements, ants can offset pollen limitation in isolated females of wind-pollinated plants with separate sexes. We propose that ants enhance plant reproductive success via targeted delivery of airborne pollen, through frequent contact with ovule tips while consuming PDs. Our study constitutes the first experimental quantification of distance-dependent contribution of ants to pollination and provides a working hypothesis for ambophily in other dioecious plants lacking pollinator reward in male plants.Fil: Aranda Rickert, Adriana Marina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; ArgentinaFil: Torrens, Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; ArgentinaFil: Yela, Natalia Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; ArgentinaFil: Brizuela, Maria Magdalena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; ArgentinaFil: Di Stilio, Verónica Sandra. University of Washington; Estados Unido

    Enhancing hepatic fatty acid oxidation as a strategy for reversing metabolic disorders programmed by maternal undernutrition during gestation

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    Background/Aims: Moderate maternal calorie-restriction during gestation programmes offspring for a major propensity to develop metabolic alterations in adulthood. We aimed to assess whether increased hepatic fatty-acid oxidation (FAO), at early ages, by gene transfer of Cpt1am (active mutant of carnitine palmitoyltransferase-1a), may be a strategy for reversing metabolic disturbances associated to maternal calorie-restriction during gestation in rats. Methods: AAV-Gfp (control) and AAV-Cpt1am vectors were administered by tail vein injection in 18-day-old control-pups and the offspring of 20% calorie-restricted rats during gestation (CR). After weaning, animals were fed with normal-fat diet. At the age of 4 months, they were moved to HF-diet and sacrificed at the age of 6 months to collect tissues. Locomotive activity, energy expenditure and blood pressure were measured. Results: Under HF-diet, CR-animals showed higher HOMA-IR, adipocyte diameter and hepatic triglyceride accumulation than controls; these alterations were reverted in Cpt1am-injected animals. In liver, this treatment ameliorated inflammatory state, decreased expression of lipogenesis-related genes and partially restored the decreased expression of leptin-receptor occurring in CR-animals. Treatment also reverted the decreased energy expenditure and the increased blood pressure of CR-animals. Conclusion: Increasing hepatic FAO through AAV-Cpt1am injection at juvenile ages prevents some metabolic disorders associated to gestational maternal calorie-restriction

    ESTUDO DO IMPACTO AMBIENTAL NA BACIA DO RIO DO BRAÇO ATRAVÉS DE ANÁLISES ECOTOXICOLÓGICAS.

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    O município de Joinville (SC) vem sofrendo com a degradação ambiental provocada pelos despejos industriais, pelo lançamento de esgotos domésticos, pela utilização de agrotóxicos e fertilizantes. Uma vez que o rio do Braço é um importante contribuinte da bacia do rio Cubatão, devido a sua localização geográfica (zona industrial, rural e urbana), seu monitoramento se torna cada vez mais necessário, especialmente quanto à qualidade de suas águas. Para as análises ecotoxicológicas, dos quatro pontos selecionados na bacia, foram utilizados para água os organismos Daphnia similis (Claus, 1876) e para sedimento Hyalella azteca (Saussere, 1858). Os resultados obtidos nas amostras de água não demonstraram efeito tóxico agudo, entretanto nas amostras de sedimentos 3 pontos indicaram toxicidade aguda ao organismo, demonstrando, dessa forma, a necessidade de monitoramento contínuo e de estudos mais detalhados na região. Palavras-chave: atividades antrópicas, corpos hídricos, ecotoxicologia ABSTRACT EVALUATION OF THE ENVIRONMENTAL IMPACT IN HYDROGRAPHIC BASIN OF THE ARM RIVER THROUGH ECOTOXICOLOGICAL ANALYSIS. The city of Joinville (SC) has suffered from environmental degradation caused by industrial waste, release of sewage and the use of pesticides and fertilizers. Since the Arm River is na important contributor to the basin of Cubatão, due to its geographical location (industrial area, rural and urban), its monitoring becomes increasingly necessary, especially regarding the quality of its waters. For the ecotoxicological tests, the four selected points in the basin were used Daphnia similis for water and Hyalella azteca for sediments. The results obtained in the water samples showed no acute toxic effect, however, in samples of sediments colon indicated acute toxicity to the body, thus demonstrating the need for ongoing monitoring and more detailed studies in the region. Key words: anthropogenic activities, water bodies, ecotoxicolog

    Effects of Albumin on Survival after a Hepatic Encephalopathy Episode: Randomized Double-Blind Trial and Meta-Analysis

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    Albúmina; Assaig clínic; MetanàlisiAlbumin; Clinical trial; Meta-analysisAlbúmina; Ensayo clínico; MetaanálisisNo therapies have been proven to increase survival after a hepatic encephalopathy (HE) episode. We hypothesize that two doses of albumin could improve 90-day survival rates after a HE episode. Methods: (1) A randomized double-blind, placebo-controlled trial (BETA) was conducted in 12 hospitals. The effect of albumin (1.5 g/kg at baseline and 1 g/kg on day 3) on 90-day survival rates after a HE episode grade II or higher was evaluated. (2) A meta-analysis of individual patient’s data for survival including two clinical trials (BETA and ALFAE) was performed. Results: In total, 82 patients were included. Albumin failed to increase the 90-day transplant-free survival (91.9% vs. 80.5%, p = 0.3). A competing risk analysis was performed, observing a 90-day cumulative incidence of death of 9% in the albumin group vs. 20% in the placebo (p = 0.1). The meta-analysis showed a benefit in the albumin group, with a lower rate of clinical events (death or liver transplant) than patients in the placebo (HR, 0.44; 95% CI, 0.21–0.82), when analyzed by a competing risk analysis (90-days mortality rate of 11% in the albumin group vs. 30% in the placebo, p = 0.02). Conclusions: Repeated doses of albumin might be beneficial for patient’s survival as an add-on therapy after an HE episode, but an adequately powered trial is needed.This work was supported by grants ICI14/00352 and PI/18/00947 from Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union (ERDF/ESF, “Investing in your future”—Una manera de hacer Europa). MVC and MST are both recipients of Juan Rodes grants from ISCIII. JG is a recipient of a research intensification grant from the ISCIII. CIBERehd is supported by ISCIII. ACS is a recipient of the Rio Hortega grant from ISCIII. The work was independent of all funding
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