El clima vitícola de las principales regiones productoras de uvas para vino en España.

La historia vitícola de España mantiene una larga tradición. Entre sus antecedentes principales figuran fenicios, griegos y cartagineses, y ya en el siglo VI a.C. era conocido el arte de la vitivinicultura en el legendario reino de Tartesos, al suroeste de la península Ibérica. Sin embargo, el cultivo de la vid y la producción de vino se extienden por la mayor parte del país durante la dominación romana y la posterior romanización. De acuerdo con escritores de la época como Plinio, Marcial, Columela, Estrabón... podemos afirmar que los legionarios romanos valoraron y extendieron el vino de Iberia por la mayor parte del Imperio y, particularmente, lo acercaron a su capital Roma

From macro to nano: Linking quantitative CEUS perfusion parameters to CD4+ T cells subtypes in spondyloarthtitis

The onset and progression of immune-mediated inflammatory arthritis, such as rheumatoid arthritis and spondyloarthritis, are linked to the IL23-IL17 immune axis, so that many therapeutic strategies aim at modulating this pathway. However, there is so far no possibility of an in vivo direct monitoring, without a biopsy, of the specific T cells involved in this modulation. Synovial perfusion, and thus synovial angiogenesis, has been recognized as a sensitive and early marker of inflammation that can be evaluated via quantitative analysis of contrast-enhanced ultrasound imaging data. © 2017 IEEE

Seleção de marcadores moleculares para caracterização genética da cultivar de videira Moscato Branco.

Este trabalho visa caracterizar um grupo de marcadores moleculares para estabelecer as diferenças entre a 'Moscato Branco' e outras cultivares moscatel cultivadas na Serra Gaúcha

Uso de marcadores moleculares microssatélites para caracterização de uva 'Moscato Branco' cultivada na serra gaúcha.

Na Serra Gaúcha a uva 'Moscato Branco' é cultivada com sucesso desde 1930, com fortes evidências indicando sua produção exclusiva ao Brasil. Para contribuir com a caracterização da cultivar utilizou-se um grupo de 17 marcadores microssatélites. O DNA foi extraído de sete amostras de folhas jovens de 'Moscato Branco', coletadas em áreas de produtores, e nove amostras de outras uvas tipo moscatel cultivadas na região, amplificado em reação de PCR e separado em gel de poliacrilamida 6%, corado com prata. Os marcadores foram caracterizados com o uso do programa GDA

Criteria used in the specifications for geographical indications of fine wines in Brazil / Critères utilisés dans les cahiers des charges des indications géographiques des vins fins au Brésil.

The Brazilian legislation on geographical indications (GI) are the Law 9.279 and INPI Normative Instruction 25/2013, establishing the conditions for the registration of GI, whether in modality of ?Indicação de Procedência? (IP) or ?Denominação de Origem? (DO). Brazil has recognized some GI of fine wines - IP Vale dos Vinhedos, Pinto Bandeira, Altos Montes, Monte Belo and Farroupilha,and DO Vale dos Vinhedos. Others are in structuring process -Campanha Gaúcha,Vale do São Francisco and Altos de Pinto Bandeira. Even without detailing, by INPI, the elements that must be in the specification document, the GI already recognized include, among others: delimited geographical area; varieties of Vitis vinifera authorized; grape production in the delimited area; training systems; maximum productivity; quality of grapes for wine making; authorized wines; oenological practices; physicochemical characteristics for each type of wine and mandatory sensory analysis; elaboration, aging and bottling in the delimited area; labeling standards. In addition, for each GI there is a specific plan of control. It is possible to observe that the specifications for Brazilian GI of wines have some similarity to those adopted in the European Community, and are more specific and demanding than most of the existing GI in the New World.Também publicado em: WORLD VINE AND WINE CONGRESS, 39.; GENERAL ASSEMBLY OF THE OIV, 14., 2016, Bento Gonçalves. Vitiviniculture: technological advances to market challenges: abstracts. Bento Gonçalves: International Organisation of Vine and Wine, 201

Aroma de vinhos Lorena elaborados com diferentes leveduras.

A liberação dos terpenos em uvas moscatéis, pela ação de glicosidases das leveduras, pode aumentar e/ou modificar o aroma de vinhos. Este experimento comparou as características sensoriais de vinhos BRS Lorena (Malvasia Bianca x Seyval) elaborados com diferentes leveduras.Resumo

Quantitative imaging by pixel-based contrast-enhanced ultrasound reveals a linear relationship between synovial vascular perfusion and the recruitment of pathogenic IL-17A-F+IL-23+ CD161+ CD4+ T helper cells in psoriatic arthritis joints

To develop quantitative imaging biomarkers of synovial tissue perfusion by pixel-based contrast-enhanced ultrasound (CEUS), we studied the relationship between CEUS synovial vascular perfusion and the frequencies of pathogenic T helper (Th)-17 cells in psoriatic arthritis (PsA) joints. Eight consecutive patients with PsA were enrolled in this study. Gray scale CEUS evaluation was performed on the same joint immediately after joint aspiration, by automatic assessment perfusion data, using a new quantification approach of pixel-based analysis and the gamma-variate model. The set of perfusional parameters considered by the time intensity curve includes the maximum value (peak) of the signal intensity curve, the blood volume index or area under the curve, (BVI, AUC) and the contrast mean transit time (MTT). The direct ex vivo analysis of the frequencies of SF IL17A-F+CD161+IL23+ CD4+ T cells subsets were quantified by fluorescence-activated cell sorter (FACS). In cross-sectional analyses, when tested for multiple comparison setting, a false discovery rate at 10%, a common pattern of correlations between CEUS Peak, AUC (BVI) and MTT parameters with the IL17A-F+IL23+ - IL17A-F+CD161+ - and IL17A-F+CD161+IL23+ CD4+ T cells subsets, as well as lack of correlation between both peak and AUC values and both CD4+T and CD4+IL23+ T cells, was observed. The pixel-based CEUS assessment is a truly measure synovial inflammation, as a useful tool to develop quantitative imaging biomarker for monitoring target therapeutics in PsA. © 2016, International League of Associations for Rheumatology (ILAR)

The Effect of Viticultural Climate on Red and White Wine Typicity - Characterization in Ibero-American grape-growing regions

Aim: This study is part of a CYTED (Ibero-American Program for Science, Technology and Development) project on vitivinicultural zoning. The objective was to characterize the effect of viticultural climate on red and white wine typicity in the macro Ibero-American viticultural region. Methods and results: The climate of 46 grape-growing regions in 6 Ibero-American countries (Argentina, Bolivia, Brazil, Chile, Spain and Portugal) was characterized using the three viticultural climate index of the Geoviticulture MCC System: the Heliothermal index HI, the Cool Night index CI and the Dryness index DI. The main sensory characteristics frequently observed in representative red and white wines of each of these regions were described by enology experts in the respective countries: intensity of colour, aroma, aroma-ripe fruit, body-palate concentration, alcohol, tannins (for red wines) and acidity as well as persistence on the palate. The data were submitted to a correlation analysis of the variables and Principal Component Analysis (PCA). Conclusion: The typicity of red and white wines was correlated with the HI, CI and DI viticultural climate indexes from the MCC System. The main wine sensory variables affected by viticultural climate were identified. Significance and impact of the study : The results can be used to project the potential impacts of climate change on wine sensory characteristics