Phthiriasis Palpebrarum – a rare case of pubic lice infestation on eyelashes

Authors report a rare case of pubic lice infestation on eyelashes – Phthiriasis Palpebrarum. Phthiriasis palpebrarum is an ectoparasitosis in which Phthirus pubis, normally affecting pubic area infest the eyelashes. Due to the fact that eyelashes are not the optimal habitat of pubic lice the clinical picture is uncommon

Efficacy and tolerance of 2,3-diphenylcyclopropenone in propylene glycol versus 2,3-diphenylcyclopropenone in isopropanol – a novel formula designed for the treatment of alopecia areata

Introduction: Topical immunotherapy of alopecia areata (AA) with contact allergens including 2,3-diphenylcyclopropenone (DCP) have been used for few decades. Aim: The study introduces a new preparation of DCP in isopropanol for the purpose of the treatment of AA. The aim of the study was to compare new formula with the previously used DCP in propylene glycol. Two groups of twenty patients each, treated with new and old formula respectively were observed for one year. Treatment efficacy and tolerance was then measured and compared. Result: All but one patient responded to the study with partial or complete hair regrowth. Results show improvement after the treatment in both groups with 75% and 85% of patients with cosmetically acceptable hair amount (grades 1 and 2 in the hair loss scale) in DCP in isopropanole and DCP in propylene glycol groups respectively. Complete hair regrowth was obtained in 35% and 25% of patients respectively. Differences in treatment’s efficacy between groups were not statistically important (p = 0.95). Tolerance was generally good but significantly better (p= 0.17) in a group treated with DCP in isopropanol. Discussion: DCP solutions in isopropanol may have potential in the treatment of alopecia areata. Treatment efficacy in both groups (DCP in propylene glycol and DCP in isopropanol) was the same. Tolerance of the DCP in isopropanol was significantly better than DCP in propylene glycol. Despite better tolerance of DCP in isopropanol during the proper treatment, the sensitization with 3% DCP should be done with the solution in propylene glycol

The efficacy and safety of diphenylcyclopropenone solutions in propylene glycol and isopropanol. A comparative study of two formulas used for the treatment of 100 patients with alopecia areata

Alopecia areata (AA) is a T cell-mediated autoimmune disease involving hair follicles characterized by hair loss. 2,3-diphenylcyclopropenone (DCP) is a topically administered drug intended for treating AA. The study investigates an efficacy and safety of DCP for the purpose of the treatment of AA. It presents a comparative study of two formulas: DCP in propylene glycol and DCP in isopropanol. While the treatment efficacy in both groups was very simmilar, the tolerance of the DCP in isopropanol was better than DCP in propylene glycol. Authors indicate the potential clinical applications of latter formula

Cutaneous actinomycosis. A case report

A 27 year old patient presented a swollen lesion in the right mandibular area. Prior to the visit the patient was diagnosed with acne and was treated for 6 consecutive months with oral limecycline with no positive response. During the visit the cervicofacial actinomycosis was diagnosed and the patient was administered treatment containing oral amoxycilin plus clavulanic acid among others. The skin lesion disappeared within three weeks. The authors discuss this case in spite of diagnostic difficulties of this uncommon condition, especially while differentiating from acne conglobata

Keratitis-Ichthyosis-Deafness (KID) Syndrome, case report

Keratitis-Ichthyosis-Deafness (KID) syndrome is a congenital disorder characterized by keratitis, ichthyosis, and deafness. Authors present a 10 year old by with KID syndrome. The diagnosis was based on a clinical picture, hearing evaluations and genetic research

Unusual acne conglobata case mimicking cervicofacial actinomycosis: A case report with literature review

Acne vulgaris is one of the most common skin diseases and one of the most frequent diagnoses for patients who visit a dermatologist. The present article describes one of the most severe kinds of acne – acne conglobata, which in a presence of deep inflammation and concomitant general symptoms, is often described as acne fulminans. The authors discuss about case requiring differentiation of acne conglobata and cervicofacial actinomycosis

Dermatology eponyms – sign – Lexicon (R): Part 2

Eponyms are used almost daily in the clinical practice of dermatology. And yet, information about the person behind the eponyms is difficult to find. Indeed, who is? What is this person’s nationality? Is this person alive or dead? How can one find the paper in which this person first described the disease? Eponyms are used to describe not only disease, but also clinical signs, surgical procedures, staining techniques, pharmacological formulations, and even pieces of equipment. In this article we present the symptoms starting with (R) and other. The symptoms and their synonyms, and those who have described this symptom or phenomenon