286 research outputs found
Resistance to Phytophthora Blight in the Improved Pigeonpea Lines at ICRISAT, Patancheru, India
Phytophthora blight (PB) (Phytophthora drechsleri Tucker
f. sp. cajani, Kannaiyan et al.) of pigeonpea (Cajanus
cajan (L.) Millsp.) is a disease of endemic importance.
Continuous rains and waterlogging in the seedling stage
of the crop favour PB epidemics, resulting in up to 100%
crop loss. Characteristic symptoms of the disease are
water-soaked lesions on the leaves and slightly sunken
lesions on stems and petioles. Lesions girdle the stem and
the foliage dries up. The disease was first reported in
1968 at the research farm of the Indian Agricultural
Research Institute (IARI) by Williams et al. (1968). Later
Kannaiyan et al. (1984) reported its widespread
occurrence in several parts of India
Biomass and Carbon Stock Estimation in Woody Grass (\u3cem\u3eDendrocalamus strictus\u3c/em\u3e L.) in Doon Valley, India
Bamboos commonly kown as woody grass are one of the most important species particularly in Asia, where it is frequently considered as the ātimber of the poorā (Rao et al., 1985). With about 23 genera and 136 species, India is the second largest reservoir of bamboos, next only to China (SFR, 2013 and Nath et al., 2009). Bamboos occur extensively in the managed ecosystems of Indiaāboth as plantations (and in agroforestry (scattered clumps, hedgerows on farm boundaries etc.
Dendrocalamus strictus L. is most commonly found bamboo in India. It is widely distributed in dry deciduous forests and grows rapidly in all climatic conditions and occupies about 53 % of total bamboo area in India. It grows better in the drier parts and on sandstone, granite and coarse grained soils with low moisture- retaining capacity and soils with pH range 5.5ā7.6. It grows more than 8 feet in 6ā8 months. The species is used widely for as raw material in paper mills and also for variety of purposes such as construction, agricultural implements, musical instruments, furniture etc. The species is also suitable for reclamations of degraded and ravine lands.
The accurate assessment of biomass estimates of a forest is important for many applications (Brown, 2002; Chave et al., 2004; Arora et al., 2014; Verma et al., 2014). In recent years, the carbon cycle has become an important issue in the world and plants play a major role in carbon storage. Biomass estimation enables us to estimate the amount of carbon dioxide that can be sequestered from the atmosphere. However, most of the carbon and biomass studies focus on assessing the capability of trees viz., poplar, eucalyptus, shisham, chir teak, subabul etc. The studies related to biomass and carbon stock estimation in bamboos is limited. The present study examine specifically the above ground stand biomass, biomass structure and C storage in D. strictus
The Mitochondrial Ca(2+) Uniporter: Structure, Function, and Pharmacology.
Mitochondrial Ca(2+) uptake is crucial for an array of cellular functions while an imbalance can elicit cell death. In this chapter, we briefly reviewed the various modes of mitochondrial Ca(2+) uptake and our current understanding of mitochondrial Ca(2+) homeostasis in regards to cell physiology and pathophysiology. Further, this chapter focuses on the molecular identities, intracellular regulators as well as the pharmacology of mitochondrial Ca(2+) uniporter complex
Nonsurgical and surgical periodontal therapy in single-rooted teeth
The purpose of this study was to compare the effect of tooth related and patient related factors on the success of non-surgical and surgical periodontal therapy. In 41 patients (22 female) with untreated and/or recurrent periodontitis, no therapy, scaling and root planing (SRP), or access flap (AF) were assigned according to probing pocket depth (PPD). PPD and vertical relative attachment level (RAL-V) were obtained initially, 3 and 6Ā months after therapy. Baseline data were compared according to therapy, jaw, tooth type, and site. Factors influencing clinical parameters were identified using multilevel analyses. Baseline PPDs were deeper interproximally, in the maxilla and at premolars compared to buccal/oral sites, mandibular, and anterior teeth. At 6Ā months, PPD reduction and RAL-V gain were significantly greater at sites receiving SRP and AF as compared to untreated sites (pā<ā0.001). PPD reduction and RAL-V gain were significantly less (pā<ā0.005) in smokers as compared to nosmokers and at interproximal sites (pā<ā0.0001) as compared to buccal/oral sites. RAL-V gain was less in aggressive periodontitis, and PPD reduction was less in the maxilla (pā<ā0.001). In sites with greater bone loss and infrabony defects, a poorer response was observed regarding RAL-V gain or PPD reduction, respectively. The conclusions of the study are the following: (1) Nonsurgical and surgical periodontal therapies are effective in single-rooted teeth; (2) severe interproximal bone loss and infrabony defects deteriorate clinical results; and (3) there seem to be more defect-associated (tooth, site) factors influencing treatment outcome than patient-associated factors
SPARC 2017 retrospect & prospects : Salford postgraduate annual research conference book of abstracts
Welcome to the Book of Abstracts for the 2017 SPARC conference. This year we not only celebrate the work of our PGRs but also the 50th anniversary of Salford as a University, which makes this yearās conference extra special. Once again we have received a tremendous contribution from our postgraduate research community; with over 130 presenters, the conference truly showcases a vibrant PGR community at Salford. These abstracts provide a taster of the research strengths of their works, and provide delegates with a reference point for networking and initiating critical debate. With such wide-ranging topics being showcased, we encourage you to exploit this great opportunity to engage with researchers working in different subject areas to your own. To meet global challenges, high impact research inevitably requires interdisciplinary collaboration. This is recognised by all major research funders. Therefore engaging with the work of others and forging collaborations across subject areas is an essential skill for the next generation of researchers
The preparation of HEMA-MPC films for ocular drug delivery
There is a need to prolong drug residence time using a biocompatible formulation in the subconjunctival space after surgery to treat glaucoma. Drug releasing discs were prepared with 2-(hydroxyethyl)methacrylate (HEMA) and 2-methacryloyl-oxyethyl phosphorylcholine (MPC). The ratio of bound water (Wb) to free water (Wf) ratio increased from 1:0.3 to 1:6.8 with increasing MPC (0 to 50%, w/w). The optimal balance between water content, SR and mechanical strength were obtained with 10% MPC (w/w) hydrogels. Water-alcohol mixtures were examined to facilitate loading of poorly soluble drugs, and they showed greater hydrogel swelling than either water or alcohol alone. The SR was 1.2 Ā± 0.02 and 3.3 Ā± 0.1 for water and water:ethanol (1:1) respectively. HEMA-MPC (10%) discs were loaded with dexamethasone using either water:ethanol (1:1) or methanol alone. Drug release was examined in an outflow rig model that mimics the subconjunctival space in the eye. Dexamethasone loading increased from 0.3 to 1.9 mg/disc when the solvent was changed from water:ethanol (1:1) to methanol with the dexamethasone half-life (tĀ½) increasing from 1.9 to 9.7 days respectively. These encouraging results indicate that HEMA-MPC hydrogels have the potential to sustain the residence time of a drug in the subconjunctival space of the eye
RNAi for Treating Hepatitis B Viral Infection
Chronic hepatitis B virus (HBV) infection is one of the leading causes of liver cirrhosis and hepatocellular carcinoma (HCC). Current treatment strategies of HBV infection including the use of interferon (IFN)-Ī± and nucleotide analogues such as lamivudine and adefovir have met with only partial success. Therefore, it is necessary to develop more effective antiviral therapies that can clear HBV infection with fewer side effects. RNA interference (RNAi), by which a small interfering RNA (siRNA) induces the gene silence at a post-transcriptional level, has the potential of treating HBV infection. The successful use of chemically synthesized siRNA, endogenous expression of small hairpin RNA (shRNA) or microRNA (miRNA) to silence the target gene make this technology towards a potentially rational therapeutics for HBV infection. However, several challenges including poor siRNA stability, inefficient cellular uptake, widespread biodistribution and non-specific effects need to be overcome. In this review, we discuss several strategies for improving the anti-HBV therapeutic efficacy of siRNAs, while avoiding their off-target effects and immunostimulation. There is an in-depth discussion on the (1) mechanisms of RNAi, (2) methods for siRNA/shRNA production, (3) barriers to RNAi-based therapies, and (4) delivery strategies of siRNA for treating HBV infection
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