Pengaruh Keterampilan Kerja Disiplin Kerja dan Lingkungan Kerja terhadap Kinerja Pegawai pada Dinas Pemuda dan Olahraga (Dispora) Manado

Kinerja merupakan perilaku yang nyata yang ditampilkan sebagai hasil kerja dari individu maupun organisasi yang dicapai untuk keberhasilan organisasi. Keterampilan kerja, disiplin kerja dan lingkungan kerja merupakan salah satu faktor yang dapat meningkatkan kinerja pegawai. Penelitian ini dilakukan pada Dinas Pemuda dan Olahraga (Dispora) manado, penelitian ini dilakukan selama enam bulan. Tujuan penelitian ini adalah untuk mengetahui pengaruh keterampilan kerja, Disiplin kerja, dan Lingkungan kerja secara simultan atau parsial terhadap kinerja pegawai Dinas Pemuda dan Olahraga (Dispora) Manado. Populasi penelitian berjumlah 40 responden. Metode penelitian asosiatif, jenis data yang digunakan adalah data kuantitatif dan sumber data adalah data primer dan sekunder. Alat ukur yang digunakan untuk menguji instrument dalam penelitian ini adalah uji validitas dan uji rehabilitas. Uji hipotesis yang digunakan adalah uji f dan uji t.sedangkan untuk menganalisis data menggunakan teknik analisis regresi linear berganda. Perhitungan statistic dilakukan dengan menggunakan bantuan program SPSS 20. Hasil penelitian menunjukan secara simultan keterampilan kerja, disiplin kerja, dan lingkungan kerja mempunyai pengaruh signifikan terhadap kinerja pegawai. Hasil penelitian secara parsial keterampilan kerja dan disiplin kerja berpengaruh signifikan terhadap kinerja pegawai, sedangkan lingkungan kerja tidak berpengaruh secara signifikan terhadap kinerja pegawai

Do Staphylococcus epidermidis genetic clusters predict isolation sources?

Staphylococcus epidermidis is a ubiquitous colonizer of human skin and a common cause of medical device-associated infections. The extent to which the population genetic structure of S. epidermidis distinguishes commensal from pathogenic isolates is unclear. Previously, Bayesian clustering of 437 multilocus sequence types (STs) in the international database revealed a population structure of six genetic clusters (GCs) that may reflect the species' ecology. Here, we first verified the presence of six GCs, including two (GC3 and GC5) with significant admixture, in an updated database of 578 STs. Next, a single nucleotide polymorphism (SNP) assay was developed that accurately assigned 545 (94%) of 578 STs to GCs. Finally, the hypothesis that GCs could distinguish isolation sources was tested by SNP typing and GC assignment of 154 isolates from hospital patients with bacteremia and those with blood culture contaminants and from nonhospital carriage. GC5 was isolated almost exclusively from hospital sources. GC1 and GC6 were isolated from all sources but were overrepresented in isolates from nonhospital and infection sources, respectively. GC2, GC3, and GC4 were relatively rare in this collection. No association was detected between fdh-positive isolates (GC2 and GC4) and nonhospital sources. Using a machine learning algorithm, GCs predicted hospital and nonhospital sources with 80% accuracy and predicted infection and contaminant sources with 45% accuracy, which was comparable to the results seen with a combination of five genetic markers (icaA, IS256, sesD [bhp], mecA, and arginine catabolic mobile element [ACME]). Thus, analysis of population structure with subgenomic data shows the distinction of hospital and nonhospital sources and the near-inseparability of sources within a hospital

The Effect of Imatinib Mesylate for Newly Diagnosed Philadelphia Chromosome-Positive, Chronic-Phase Myeloid Leukemia in Sub-Saharan African Patients: The Experience of Côte d'Ivoire

Imatinib mesylate, showed encouraging activity in chronic myelogenous leukemia. However, there are few data regarding his efficacy and response monitoring in Sub-Saharan African patients. Our objective was to assess response to imatinib mesylate (Glivec) in Côte d'Ivoire patients with newly diagnosed Chronic Myeloid Leukemia (CML). From May 2005 to September 2009, we treated 42 patients (40 years; range 16–69) with Philadelphia chromosome (Ph+) positive in chronic phase CML with oral imatinib mesylate at daily doses of 400 mg. Overall survival (OS) and frequency of complete or major cytogenetic remission (CCR/MCR) were evaluated. At a median follow up of 32 (range 7.6–113) months, the CHR rate in our study group was 76%. A major CR was found in 19 patients (45%) with 17% and 29% complete and partial CR respectively. There were no significant differences in the incidence of major cytogenetic response by known prognostics factors. Median time to CHR was 8 months (range 0.4–25), and 16 months (range: 0.1–36) for CR. Projected 5-year OS rate was 72% (95%CI 42–88). We conclude that imatinib therapy sub-Saharan African CML patients is very promising and has favorably changed the prognosis for black African patients with CML

SOSORT consensus paper: school screening for scoliosis. Where are we today?

This report is the SOSORT Consensus Paper on School Screening for Scoliosis discussed at the 4th International Conference on Conservative Management of Spinal Deformities, presented by SOSORT, on May 2007. The objectives were numerous, 1) the inclusion of the existing information on the issue, 2) the analysis and discussion of the responses by the meeting attendees to the twenty six questions of the questionnaire, 3) the impact of screening on frequency of surgical treatment and of its discontinuation, 4) the reasons why these programs must be continued, 5) the evolving aim of School Screening for Scoliosis and 6) recommendations for improvement of the procedure

2011 SOSORT guidelines: Orthopaedic and Rehabilitation treatment of idiopathic scoliosis during growth

<p>Abstract</p> <p>Background</p> <p>The International Scientific Society on Scoliosis Orthopaedic and Rehabilitation Treatment (SOSORT), that produced its first Guidelines in 2005, felt the need to revise them and increase their scientific quality. The aim is to offer to all professionals and their patients an evidence-based updated review of the actual evidence on conservative treatment of idiopathic scoliosis (CTIS).</p> <p>Methods</p> <p>All types of professionals (specialty physicians, and allied health professionals) engaged in CTIS have been involved together with a methodologist and a patient representative. A review of all the relevant literature and of the existing Guidelines have been performed. Documents, recommendations, and practical approach flow charts have been developed according to a Delphi procedure. A methodological and practical review has been made, and a final Consensus Session was held during the 2011 Barcelona SOSORT Meeting.</p> <p>Results</p> <p>The contents of the document are: methodology; generalities on idiopathic scoliosis; approach to CTIS in different patients, with practical flow-charts; literature review and recommendations on assessment, bracing, physiotherapy, Physiotherapeutic Specific Exercises (PSE) and other CTIS. Sixty-five recommendations have been given, divided in the following topics: Bracing (20 recommendations), PSE to prevent scoliosis progression during growth (8), PSE during brace treatment and surgical therapy (5), Other conservative treatments (3), Respiratory function and exercises (3), Sports activities (6), Assessment (20). No recommendations reached a Strength of Evidence level I; 2 were level II; 7 level III; and 20 level IV; through the Consensus procedure 26 reached level V and 10 level VI. The Strength of Recommendations was Grade A for 13, B for 49 and C for 3; none had grade D.</p> <p>Conclusion</p> <p>These Guidelines have been a big effort of SOSORT to paint the actual situation of CTIS, starting from the evidence, and filling all the gray areas using a scientific method. According to results, it is possible to understand the lack of research in general on CTIS. SOSORT invites researchers to join, and clinicians to develop good research strategies to allow in the future to support or refute these recommendations according to new and stronger evidence.</p

El "Microespacio" desde una perspectiva etnoarqueológica

Ponencia presentada en el Coloquio sobre el microespacio celebrado entre el 15 y el 17 de septiembre en Teruel en 1986. Entidad organizadora: Seminario de Arqueología y Etnología Turolense, Colegio Universitario de Teruel[ES] En este trabajo se exponen los requisitos que según los autores debe reunir una investigación etnoarqueológica para que dentro de una metodología científica, pueda ser util a los arqueólogos prehistoriadores.[FR] Dans ce travail on expose les caractéristiques que selon les auteurs doit reunir une recherche ethno-archeologique a fin d'etre vraiment utile, dedans une méthodologie cientifique, aux archéologues préhistoriens.Peer reviewe